diff --git a/docs/commands/blobs.md b/docs/commands/blobs.md
index a0a6fb52b4f..de0ddc7425b 100644
--- a/docs/commands/blobs.md
+++ b/docs/commands/blobs.md
@@ -39,6 +39,7 @@ netlify blobs:set my-store my-key --input ./some-file.txt
 netlify blobs:delete my-store my-key
 netlify blobs:list my-store
 netlify blobs:list my-store --json
+netlify blobs:list my-store --region eu-central-1
 ```
 
 ---
@@ -61,6 +62,7 @@ netlify blobs:delete
 
 - `filter` (*string*) - For monorepos, specify the name of the application to run the command in
 - `force` (*boolean*) - Bypasses prompts & Force the command to run.
+- `region` (*string*) - The region where the store data is held, such as 'eu-central-1'; when omitted, the default region is used
 - `debug` (*boolean*) - Print debugging information
 - `auth` (*string*) - Netlify auth token - can be used to run this command without logging in
 
@@ -84,6 +86,7 @@ netlify blobs:get
 
 - `filter` (*string*) - For monorepos, specify the name of the application to run the command in
 - `output` (*string*) - Defines the filesystem path where the blob data should be persisted
+- `region` (*string*) - The region where the store data is held, such as 'eu-central-1'; when omitted, the default region is used
 - `debug` (*boolean*) - Print debugging information
 - `auth` (*string*) - Netlify auth token - can be used to run this command without logging in
 
@@ -110,6 +113,7 @@ netlify blobs:list
 - `prefix` (*string*) - A string for filtering down the entries; when specified, only the entries whose key starts with that prefix are returned
 - `debug` (*boolean*) - Print debugging information
 - `auth` (*string*) - Netlify auth token - can be used to run this command without logging in
+- `region` (*string*) - The region where the store data is held, such as 'eu-central-1'; when omitted, the default region is used
 
 ---
 ## `blobs:set`
@@ -133,6 +137,7 @@ netlify blobs:set
 - `filter` (*string*) - For monorepos, specify the name of the application to run the command in
 - `force` (*boolean*) - Bypasses prompts & Force the command to run.
 - `input` (*string*) - Defines the filesystem path where the blob data should be read from
+- `region` (*string*) - The region where the store data is held, such as 'eu-central-1'; when omitted, the default region is used
 - `debug` (*boolean*) - Print debugging information
 - `auth` (*string*) - Netlify auth token - can be used to run this command without logging in
 
diff --git a/src/commands/blobs/blobs-delete.ts b/src/commands/blobs/blobs-delete.ts
index 8b877670b7a..0a7fac02e7d 100644
--- a/src/commands/blobs/blobs-delete.ts
+++ b/src/commands/blobs/blobs-delete.ts
@@ -1,4 +1,4 @@
-import { getStore } from '@netlify/blobs'
+import { getStore, type GetStoreOptions } from '@netlify/blobs'
 
 import { chalk, logAndThrowError, log } from '../../utils/command-helpers.js'
 import { promptBlobDelete } from '../../utils/prompts/blob-delete-prompts.js'
@@ -13,6 +13,7 @@ export const blobsDelete = async (storeName: string, key: string, _options: Reco
   const store = getStore({
     apiURL: `${api.scheme}://${api.host}`,
     name: storeName,
+    region: _options.region as GetStoreOptions['region'],
     siteID: siteInfo.id ?? '',
     token: api.accessToken ?? '',
   })
diff --git a/src/commands/blobs/blobs-get.ts b/src/commands/blobs/blobs-get.ts
index 0b105e97d05..45d72dd2ded 100644
--- a/src/commands/blobs/blobs-get.ts
+++ b/src/commands/blobs/blobs-get.ts
@@ -1,7 +1,7 @@
 import { promises as fs } from 'fs'
 import { resolve } from 'path'
 
-import { getStore } from '@netlify/blobs'
+import { getStore, type GetStoreOptions } from '@netlify/blobs'
 import { OptionValues } from 'commander'
 
 import { chalk, logAndThrowError } from '../../utils/command-helpers.js'
@@ -9,6 +9,7 @@ import BaseCommand from '../base-command.js'
 
 interface Options extends OptionValues {
   output?: string
+  region?: GetStoreOptions['region']
 }
 
 export const blobsGet = async (storeName: string, key: string, options: Options, command: BaseCommand) => {
@@ -17,6 +18,7 @@ export const blobsGet = async (storeName: string, key: string, options: Options,
   const store = getStore({
     apiURL: `${api.scheme}://${api.host}`,
     name: storeName,
+    region: options.region,
     siteID: siteInfo?.id ?? '',
     token: api.accessToken ?? '',
   })
diff --git a/src/commands/blobs/blobs-list.ts b/src/commands/blobs/blobs-list.ts
index 55844976261..f4fe717e15a 100644
--- a/src/commands/blobs/blobs-list.ts
+++ b/src/commands/blobs/blobs-list.ts
@@ -1,4 +1,4 @@
-import { getStore } from '@netlify/blobs'
+import { getStore, type GetStoreOptions } from '@netlify/blobs'
 import AsciiTable from 'ascii-table'
 import { OptionValues } from 'commander'
 
@@ -9,6 +9,7 @@ interface Options extends OptionValues {
   directories?: boolean
   json?: boolean
   prefix?: string
+  region?: GetStoreOptions['region']
 }
 
 export const blobsList = async (storeName: string, options: Options, command: BaseCommand) => {
@@ -16,6 +17,7 @@ export const blobsList = async (storeName: string, options: Options, command: Ba
   const store = getStore({
     apiURL: `${api.scheme}://${api.host}`,
     name: storeName,
+    region: options.region,
     siteID: siteInfo.id,
     token: api.accessToken ?? '',
   })
diff --git a/src/commands/blobs/blobs-set.ts b/src/commands/blobs/blobs-set.ts
index 66b34d21d6c..be8119c4617 100644
--- a/src/commands/blobs/blobs-set.ts
+++ b/src/commands/blobs/blobs-set.ts
@@ -1,7 +1,7 @@
 import { promises as fs } from 'fs'
 import { resolve } from 'path'
 
-import { getStore } from '@netlify/blobs'
+import { getStore, type GetStoreOptions } from '@netlify/blobs'
 import { OptionValues } from 'commander'
 
 import { chalk, logAndThrowError, isNodeError, log } from '../../utils/command-helpers.js'
@@ -11,6 +11,7 @@ import BaseCommand from '../base-command.js'
 interface Options extends OptionValues {
   input?: string
   force?: string | boolean
+  region?: GetStoreOptions['region']
 }
 
 export const blobsSet = async (
@@ -25,6 +26,7 @@ export const blobsSet = async (
   const store = getStore({
     apiURL: `${api.scheme}://${api.host}`,
     name: storeName,
+    region: options.region,
     siteID: siteInfo.id,
     token: api.accessToken ?? '',
   })
diff --git a/src/commands/blobs/blobs.ts b/src/commands/blobs/blobs.ts
index 62b77fd203c..39b510cee97 100644
--- a/src/commands/blobs/blobs.ts
+++ b/src/commands/blobs/blobs.ts
@@ -20,6 +20,10 @@ export const createBlobsCommand = (program: BaseCommand) => {
     .description(`Deletes an object with a given key, if it exists, from a Netlify Blobs store`)
     .argument('<store>', 'Name of the store')
     .argument('<key>', 'Object key')
+    .option(
+      '--region <region>',
+      "The region where the store data is held, such as 'eu-central-1'; when omitted, the default region is used",
+    )
     .alias('blob:delete')
     .hook('preAction', requiresSiteInfo)
     .action(async (storeName: string, key: string, _options: OptionValues, command: BaseCommand) => {
@@ -35,6 +39,10 @@ export const createBlobsCommand = (program: BaseCommand) => {
     .argument('<store>', 'Name of the store')
     .argument('<key>', 'Object key')
     .option('-O, --output <path>', 'Defines the filesystem path where the blob data should be persisted')
+    .option(
+      '--region <region>',
+      "The region where the store data is held, such as 'eu-central-1'; when omitted, the default region is used",
+    )
     .alias('blob:get')
     .hook('preAction', requiresSiteInfo)
     .action(async (storeName: string, key: string, options: OptionValues, command: BaseCommand) => {
@@ -55,6 +63,10 @@ export const createBlobsCommand = (program: BaseCommand) => {
       `A string for filtering down the entries; when specified, only the entries whose key starts with that prefix are returned`,
     )
     .option('--json', 'Output list contents as JSON')
+    .option(
+      '--region <region>',
+      "The region where the store data is held, such as 'eu-central-1'; when omitted, the default region is used",
+    )
     .alias('blob:list')
     .hook('preAction', requiresSiteInfo)
     .action(async (storeName: string, options: OptionValues, command: BaseCommand) => {
@@ -71,6 +83,10 @@ export const createBlobsCommand = (program: BaseCommand) => {
     .argument('<key>', 'Object key')
     .argument('[value...]', 'Object value')
     .option('-i, --input <path>', 'Defines the filesystem path where the blob data should be read from')
+    .option(
+      '--region <region>',
+      "The region where the store data is held, such as 'eu-central-1'; when omitted, the default region is used",
+    )
     .alias('blob:set')
     .hook('preAction', requiresSiteInfo)
 
@@ -98,6 +114,7 @@ For more information about Netlify Blobs, see ${terminalLink(docsUrl, docsUrl, {
       'netlify blobs:delete my-store my-key',
       'netlify blobs:list my-store',
       'netlify blobs:list my-store --json',
+      'netlify blobs:list my-store --region eu-central-1',
     ])
     .action(blobs)
 }
diff --git a/tests/integration/commands/blobs/blobs.test.ts b/tests/integration/commands/blobs/blobs.test.ts
index 6fa7187a07f..c80ac7c26aa 100644
--- a/tests/integration/commands/blobs/blobs.test.ts
+++ b/tests/integration/commands/blobs/blobs.test.ts
@@ -27,6 +27,7 @@ describe('blobs:* commands', () => {
   const directory = temporaryDirectory()
 
   let server: BlobsServer
+  const requestedURLs: string[] = []
   const routes: Route[] = [
     { path: 'sites/site_id', response: siteInfo },
 
@@ -50,6 +51,7 @@ describe('blobs:* commands', () => {
       method: 'all',
       path: 'blobs/{*splat}',
       response: (req, res) => {
+        requestedURLs.push(req.url)
         blobsProxy.web(req, res, { target: `http://localhost:${address.port}` })
       },
     })
@@ -118,5 +120,36 @@ describe('blobs:* commands', () => {
         }),
       ).rejects.toThrowError('Error: Blob my-key does not exist in store my-store')
     })
+
+    test<FixtureTestContext>('should send the region to the API when one is given', async ({ fixture }) => {
+      const region = 'eu-central-1'
+
+      requestedURLs.length = 0
+      await fixture.callCli(['blobs:list', 'my-store', '--region', region, '--json'], {
+        offline: false,
+        parseJson: true,
+      })
+
+      expect(requestedURLs.some((url) => url.includes(`region=${region}`))).toBe(true)
+    })
+
+    test<FixtureTestContext>('should not send a region when none is given', async ({ fixture }) => {
+      requestedURLs.length = 0
+      await fixture.callCli(['blobs:list', 'my-store', '--json'], {
+        offline: false,
+        parseJson: true,
+      })
+
+      expect(requestedURLs.length).toBeGreaterThan(0)
+      expect(requestedURLs.some((url) => url.includes('region'))).toBe(false)
+    })
+
+    test<FixtureTestContext>('should reject a region the Blobs client does not support', async ({ fixture }) => {
+      await expect(
+        fixture.callCli(['blobs:list', 'my-store', '--region', 'mars-north-1', '--json'], {
+          offline: false,
+        }),
+      ).rejects.toThrowError('not a supported Netlify Blobs region')
+    })
   })
 })