diff --git a/core/src/components/item-sliding/item-sliding.tsx b/core/src/components/item-sliding/item-sliding.tsx
index d2bce0e0dfd..2c0fbcc2013 100644
--- a/core/src/components/item-sliding/item-sliding.tsx
+++ b/core/src/components/item-sliding/item-sliding.tsx
@@ -422,6 +422,13 @@ export class ItemSliding implements ComponentInterface {
       style.transition = '';
     }
 
+    if (openAmount !== 0) {
+      el.classList.remove('item-sliding-closing');
+      if (this.gesture) {
+        this.gesture.enable(!this.disabled);
+      }
+    }
+
     if (openAmount > 0) {
       this.state =
         openAmount >= this.optsWidthRightSide + SWIPE_MARGIN
diff --git a/core/src/components/item-sliding/test/basic/item-sliding.e2e.ts b/core/src/components/item-sliding/test/basic/item-sliding.e2e.ts
index 66797b3ad4e..0ba173e7232 100644
--- a/core/src/components/item-sliding/test/basic/item-sliding.e2e.ts
+++ b/core/src/components/item-sliding/test/basic/item-sliding.e2e.ts
@@ -262,5 +262,21 @@ configs({ modes: ['ios'], directions: ['ltr'] }).forEach(({ title, config }) =>
 
       await openStartOptions(page, true);
     });
+
+    test('opening opposite side should remove item-sliding-closing and keep options clickable', async ({ page }, testInfo) => {
+      testInfo.annotations.push({
+        type: 'issue',
+        description: 'https://github.com/ionic-team/ionic-framework/issues/29975',
+      });
+
+      const slidingItem = page.locator('#item2');
+      await slidingItem.evaluate(async (el: HTMLIonItemSlidingElement) => {
+        await el.open('end');
+        await el.open('start');
+      });
+      await page.waitForChanges();
+
+      await expect(slidingItem).not.toHaveClass(/item-sliding-closing/);
+    });
   });
 });