diff --git a/.ci/.matrix_exclude.yml b/.ci/.matrix_exclude.yml
index c7089061f..6d8878ab8 100644
--- a/.ci/.matrix_exclude.yml
+++ b/.ci/.matrix_exclude.yml
@@ -59,6 +59,9 @@ exclude:
     FRAMEWORK: flask-3.0
   - VERSION: python-3.14
     FRAMEWORK: flask-1.0
+  # Python 3.9
+  - VERSION: python-3.9
+    FRAMEWORK: cassandra-3.24
   # Python 3.10 removed a bunch of classes from collections, now in collections.abc
   - VERSION: python-3.10
     FRAMEWORK: django-1.11
@@ -95,7 +98,7 @@ exclude:
   - VERSION: python-3.10
     FRAMEWORK: aiohttp-4.0
   - VERSION: python-3.10
-    FRAMEWORK: cassandra-3.4
+    FRAMEWORK: cassandra-3.24
   - VERSION: python-3.10
     FRAMEWORK: pymongo-3.5
   - VERSION: python-3.11
@@ -111,7 +114,7 @@ exclude:
   - VERSION: python-3.11
     FRAMEWORK: aiohttp-4.0
   - VERSION: python-3.11
-    FRAMEWORK: cassandra-3.4
+    FRAMEWORK: cassandra-3.24
   - VERSION: python-3.11
     FRAMEWORK: pymongo-3.5
   - VERSION: python-3.12
@@ -127,7 +130,7 @@ exclude:
   - VERSION: python-3.12
     FRAMEWORK: aiohttp-4.0
   - VERSION: python-3.12
-    FRAMEWORK: cassandra-3.4
+    FRAMEWORK: cassandra-3.24
   - VERSION: python-3.12
     FRAMEWORK: pymongo-3.5
   - VERSION: python-3.13
@@ -153,7 +156,7 @@ exclude:
   - VERSION: python-3.13
     FRAMEWORK: aiohttp-4.0
   - VERSION: python-3.13
-    FRAMEWORK: cassandra-3.4
+    FRAMEWORK: cassandra-3.24
   - VERSION: python-3.14
     FRAMEWORK: django-1.11
   - VERSION: python-3.14
@@ -181,7 +184,7 @@ exclude:
   - VERSION: python-3.14
     FRAMEWORK: aiohttp-4.0
   - VERSION: python-3.14
-    FRAMEWORK: cassandra-3.4
+    FRAMEWORK: cassandra-3.24
   - VERSION: python-3.14
     FRAMEWORK: pymongo-3.5
   # pymongo
@@ -353,32 +356,24 @@ exclude:
     FRAMEWORK: twisted-17
   - VERSION: python-3.11
     FRAMEWORK: twisted-16
-  - VERSION: python-3.11
-    FRAMEWORK: twisted-15
   - VERSION: python-3.12
     FRAMEWORK: twisted-18
   - VERSION: python-3.12
     FRAMEWORK: twisted-17
   - VERSION: python-3.12
     FRAMEWORK: twisted-16
-  - VERSION: python-3.12
-    FRAMEWORK: twisted-15
   - VERSION: python-3.13
     FRAMEWORK: twisted-18
   - VERSION: python-3.13
     FRAMEWORK: twisted-17
   - VERSION: python-3.13
     FRAMEWORK: twisted-16
-  - VERSION: python-3.13
-    FRAMEWORK: twisted-15
   - VERSION: python-3.14
     FRAMEWORK: twisted-18
   - VERSION: python-3.14
     FRAMEWORK: twisted-17
   - VERSION: python-3.14
     FRAMEWORK: twisted-16
-  - VERSION: python-3.14
-    FRAMEWORK: twisted-15
   # pylibmc
   - VERSION: python-3.11
     FRAMEWORK: pylibmc-1.4
@@ -416,8 +411,6 @@ exclude:
   # TODO py3.12
   - VERSION: python-3.12
     FRAMEWORK: sanic-20.12  # no wheels available yet
-  - VERSION: python-3.13
-    FRAMEWORK: cassandra-newest  # c extension issue
   - VERSION: python-3.14
     FRAMEWORK: cassandra-newest  # c extension issue
   # httpx
diff --git a/.ci/.matrix_framework_full.yml b/.ci/.matrix_framework_full.yml
index 6b3a6ea08..10c8cee73 100644
--- a/.ci/.matrix_framework_full.yml
+++ b/.ci/.matrix_framework_full.yml
@@ -36,7 +36,6 @@ FRAMEWORK:
   - twisted-18
   - twisted-17
   - twisted-16
-  - twisted-15
   - requests-newest
   - boto3-1.5
   - boto3-1.6
@@ -57,7 +56,7 @@ FRAMEWORK:
   - memcached-newest
   - pylibmc-1.4
   - pylibmc-newest
-  - cassandra-3.4
+  - cassandra-3.24
   - cassandra-newest
   - psutil-newest
   - psutil-5.0
diff --git a/docs/reference/supported-technologies.md b/docs/reference/supported-technologies.md
index 47ee5c12b..28efb9438 100644
--- a/docs/reference/supported-technologies.md
+++ b/docs/reference/supported-technologies.md
@@ -397,7 +397,7 @@ Collected trace data:
 
 #### Cassandra [automatic-instrumentation-db-cassandra]
 
-Library: `cassandra-driver` (`>=3.4,<4.0`)
+Library: `cassandra-driver` (`>=3.24,<4.0`)
 
 Instrumented methods:
 
diff --git a/tests/requirements/reqs-cassandra-3.24.txt b/tests/requirements/reqs-cassandra-3.24.txt
new file mode 100644
index 000000000..5726719a1
--- /dev/null
+++ b/tests/requirements/reqs-cassandra-3.24.txt
@@ -0,0 +1,3 @@
+cassandra-driver==3.24.0
+setuptools<82.0.0
+-r reqs-base.txt
diff --git a/tests/requirements/reqs-cassandra-3.4.txt b/tests/requirements/reqs-cassandra-3.4.txt
deleted file mode 100644
index db098c483..000000000
--- a/tests/requirements/reqs-cassandra-3.4.txt
+++ /dev/null
@@ -1,2 +0,0 @@
-cassandra-driver>=3.4.0,<3.5.0
--r reqs-base.txt
diff --git a/tests/requirements/reqs-cassandra-newest.txt b/tests/requirements/reqs-cassandra-newest.txt
index e66c6177b..bdaf637a9 100644
--- a/tests/requirements/reqs-cassandra-newest.txt
+++ b/tests/requirements/reqs-cassandra-newest.txt
@@ -1,2 +1,3 @@
-cassandra-driver>=3.14.0
+cassandra-driver<4
+setuptools<82.0.0
 -r reqs-base.txt
diff --git a/tests/requirements/reqs-tornado-newest.txt b/tests/requirements/reqs-tornado-newest.txt
index 800b85aee..6a5447d7d 100644
--- a/tests/requirements/reqs-tornado-newest.txt
+++ b/tests/requirements/reqs-tornado-newest.txt
@@ -1,3 +1,4 @@
 tornado>=6.0
 pytest-tornado
+setuptools<82.0.0
 -r reqs-base.txt
diff --git a/tests/requirements/reqs-twisted-15.txt b/tests/requirements/reqs-twisted-15.txt
deleted file mode 100644
index 084a05a3b..000000000
--- a/tests/requirements/reqs-twisted-15.txt
+++ /dev/null
@@ -1,2 +0,0 @@
-Twisted>=15,<16
--r reqs-base.txt
diff --git a/tests/scripts/envs/cassandra-3.4.sh b/tests/scripts/envs/cassandra-3.24.sh
similarity index 100%
rename from tests/scripts/envs/cassandra-3.4.sh
rename to tests/scripts/envs/cassandra-3.24.sh
diff --git a/tests/scripts/run_tests.sh b/tests/scripts/run_tests.sh
index 7fcc85010..134dc043f 100755
--- a/tests/scripts/run_tests.sh
+++ b/tests/scripts/run_tests.sh
@@ -3,7 +3,8 @@
 set -e
 
 export PATH=${HOME}/.local/bin:${PATH}
-python -m pip install --user -U pip setuptools --cache-dir "${PIP_CACHE}"
+# setuptools 82 dropped pkg_resources but that is required by some old versions of packages we are testing
+python -m pip install --user -U pip 'setuptools<82' --cache-dir "${PIP_CACHE}"
 python -m pip install --user -r "tests/requirements/reqs-${FRAMEWORK}.txt" --cache-dir "${PIP_CACHE}"
 
 export PYTHON_VERSION=$(python -c "import platform; pv=platform.python_version_tuple(); print('pypy' + ('' if pv[0] == 2 else str(pv[0])) if platform.python_implementation() == 'PyPy' else '.'.join(map(str, platform.python_version_tuple()[:2])))")