diff --git a/sagemaker-serve/src/sagemaker/serve/predictor_async.py b/sagemaker-serve/src/sagemaker/serve/predictor_async.py
index 31e94318d5..7bc164ac0e 100644
--- a/sagemaker-serve/src/sagemaker/serve/predictor_async.py
+++ b/sagemaker-serve/src/sagemaker/serve/predictor_async.py
@@ -40,6 +40,9 @@ def __init__(
             predictor (sagemaker.predictor.Predictor): General ``Predictor``
                 object has useful methods and variables. ``AsyncPredictor``
                 stands on top of it with capability for async inference.
+            name (str): Optional. Name used as the prefix of the Amazon S3 key when
+                input data is uploaded for async inference. If not specified, the
+                endpoint name is used. (Default: None)
         """
         self.predictor = predictor
         self.endpoint_name = predictor.endpoint_name
@@ -169,10 +172,13 @@ def _upload_data_to_s3(
             my_uuid = str(uuid.uuid4())
             timestamp = sagemaker_timestamp()
             bucket = self.sagemaker_session.default_bucket()
+            # ``name`` is optional; fall back to the endpoint name so the default
+            # ``AsyncPredictor(predictor)`` construction can upload input data.
+            base_name = self.name or self.endpoint_name
             key = s3.s3_path_join(
                 self.sagemaker_session.default_bucket_prefix,
                 "async-endpoint-inputs",
-                name_from_base(self.name, short=True),
+                name_from_base(base_name, short=True),
                 "{}-{}".format(timestamp, my_uuid),
             )
 
diff --git a/sagemaker-serve/tests/unit/test_predictor_async.py b/sagemaker-serve/tests/unit/test_predictor_async.py
index ccd011a973..fbeeea0bbb 100644
--- a/sagemaker-serve/tests/unit/test_predictor_async.py
+++ b/sagemaker-serve/tests/unit/test_predictor_async.py
@@ -86,6 +86,51 @@ def test_upload_data_to_s3(self, mock_parse):
         self.assertEqual(result, "s3://bucket/key")
         async_predictor.s3_client.put_object.assert_called_once()
 
+    def test_upload_data_to_s3_without_name_uses_endpoint_name(self):
+        # Regression test for https://github.com/aws/sagemaker-python-sdk/issues/3210
+        self.mock_predictor.serializer.serialize.return_value = b"serialized_data"
+
+        async_predictor = AsyncPredictor(self.mock_predictor)
+        async_predictor.sagemaker_session.default_bucket.return_value = "default-bucket"
+        async_predictor.sagemaker_session.default_bucket_prefix = None
+
+        result = async_predictor._upload_data_to_s3("test_data")
+
+        self.assertIsNone(async_predictor.name)
+        key = async_predictor.s3_client.put_object.call_args.kwargs["Key"]
+        self.assertTrue(key.startswith("async-endpoint-inputs/test-endpoint-"))
+        self.assertEqual(result, "s3://default-bucket/{}".format(key))
+
+    def test_upload_data_to_s3_with_name_uses_name(self):
+        self.mock_predictor.serializer.serialize.return_value = b"serialized_data"
+
+        async_predictor = AsyncPredictor(self.mock_predictor, name="my-async")
+        async_predictor.sagemaker_session.default_bucket.return_value = "default-bucket"
+        async_predictor.sagemaker_session.default_bucket_prefix = None
+
+        async_predictor._upload_data_to_s3("test_data")
+
+        key = async_predictor.s3_client.put_object.call_args.kwargs["Key"]
+        self.assertTrue(key.startswith("async-endpoint-inputs/my-async-"))
+
+    @patch.object(AsyncPredictor, "_submit_async_request")
+    def test_predict_async_with_data_and_no_name(self, mock_submit):
+        # Regression test for https://github.com/aws/sagemaker-python-sdk/issues/3210
+        mock_submit.return_value = {
+            "OutputLocation": "s3://bucket/output",
+            "FailureLocation": "s3://bucket/failure",
+        }
+        self.mock_predictor.serializer.serialize.return_value = b"serialized_data"
+
+        async_predictor = AsyncPredictor(self.mock_predictor)
+        async_predictor.sagemaker_session.default_bucket.return_value = "default-bucket"
+        async_predictor.sagemaker_session.default_bucket_prefix = None
+
+        response = async_predictor.predict_async(data="test_data")
+
+        self.assertEqual(response.output_path, "s3://bucket/output")
+        async_predictor.s3_client.put_object.assert_called_once()
+
     def test_delete_endpoint(self):
         async_predictor = AsyncPredictor(self.mock_predictor)
         async_predictor.delete_endpoint()