diff --git a/infra/python/deps/adls-requirements.txt b/infra/python/deps/adls-requirements.txt
index ffa41ff03a..5b4856273b 100644
--- a/infra/python/deps/adls-requirements.txt
+++ b/infra/python/deps/adls-requirements.txt
@@ -21,7 +21,7 @@
 
 pycparser == 2.23
 cffi==2.0.0
-cryptography==46.0.7
+cryptography==50.0.0
   maturin==1.13.3
     setuptools-rust==1.12.1
       semantic_version==2.10.0