diff --git a/packages/main/cypress/specs/Popover.cy.tsx b/packages/main/cypress/specs/Popover.cy.tsx
index 9c197a00f026..59920f1f0f43 100644
--- a/packages/main/cypress/specs/Popover.cy.tsx
+++ b/packages/main/cypress/specs/Popover.cy.tsx
@@ -7,6 +7,7 @@ import Label from "../../src/Label.js";
 import List from "../../src/List.js";
 import ListItem from "../../src/ListItemStandard.js";
 import Input from "../../src/Input.js";
+import Dialog from "../../src/Dialog.js";
 
 describe("Rendering", () => {
 	it("tests arrow positioning", () => {
@@ -1810,3 +1811,88 @@ describe("Responsive paddings", () => {
 		cy.get("[ui5-popover]").should("have.attr", "media-range", "M");
 	});
 });
+
+describe("Opener visibility in scrollable containers", () => {
+	it("should close popover when opener scrolls out of view in scrollable container", () => {
+		cy.mount(
+			<div id="scrollContainer" style={{ height: "200px", overflowY: "auto" }}>
+				<div style={{ height: "500px" }}>
+					<Button id="opener" style={{ marginTop: "100px" }}>Open</Button>
+					<Popover opener="opener" open={true}>
+						<div>Popover Content</div>
+					</Popover>
+				</div>
+			</div>
+		);
+
+		cy.get<Popover>("[ui5-popover]").ui5PopoverOpened();
+
+		cy.get("#scrollContainer").scrollTo(0, 200);
+
+		cy.get("[ui5-popover]").should("have.prop", "open", false);
+	});
+
+	it("should close popover when opener scrolls out in Dialog scenario", () => {
+		cy.mount(
+			<Dialog open={true}>
+				<div slot="header" style={{ height: "200px" }}>LargeHeader</div>
+				<div id="dialogScrollContainer" style={{ height: "200px", overflowY: "auto" }}>
+					<div style={{ height: "1000px" }}>
+						<Button id="dialogOpener" style={{ marginTop: "100px" }}>Opener</Button>
+						<Popover opener="dialogOpener" open={true}>
+							<div>Popover in Dialog</div>
+						</Popover>
+					</div>
+				</div>
+			</Dialog>
+		);
+
+		cy.get<Popover>("[ui5-popover]").ui5PopoverOpened();
+
+		cy.get("#dialogScrollContainer").scrollTo(0, 500);
+
+		cy.get("[ui5-popover]").should("have.prop", "open", false);
+	});
+
+	it("should work with nested scrollable containers", () => {
+		cy.mount(
+			<div style={{ height: "300px", overflowY: "auto" }}>
+				<div style={{ height: "500px" }}>
+					<div id="innerScroll" style={{ height: "150px", overflowY: "auto", marginTop: "50px" }}>
+						<div style={{ height: "800px" }}>
+							<Button id="nestedOpener" style={{ marginTop: "80px" }}>Nested Opener</Button>
+							<Popover opener="nestedOpener" open={true}>
+								<div>Nested Popover</div>
+							</Popover>
+						</div>
+					</div>
+				</div>
+			</div>
+		);
+
+		cy.get<Popover>("[ui5-popover]").ui5PopoverOpened();
+
+		cy.get("#innerScroll").scrollTo(0, 300);
+
+		cy.get("[ui5-popover]").should("have.prop", "open", false);
+	});
+
+	it("should handle horizontal scrolling", () => {
+		cy.mount(
+			<div id="horizontalScroll" style={{ width: "200px", height: "200px", overflowX: "auto" }}>
+				<div style={{ width: "1000px", height: "100px" }}>
+					<Button id="hOpener" style={{ marginLeft: "100px" }}>Horizontal Opener</Button>
+					<Popover opener="hOpener" open={true}>
+						<div>Horizontal Popover</div>
+						</Popover>
+				</div>
+			</div>
+		);
+
+		cy.get<Popover>("[ui5-popover]").ui5PopoverOpened();
+
+		cy.get("#horizontalScroll").scrollTo(500, 0);
+
+		cy.get("[ui5-popover]").should("have.prop", "open", false);
+	});
+});
diff --git a/packages/main/src/Popover.ts b/packages/main/src/Popover.ts
index 37d3379583d4..5bc66cc7c2fe 100644
--- a/packages/main/src/Popover.ts
+++ b/packages/main/src/Popover.ts
@@ -227,6 +227,7 @@ class Popover extends Popup {
 	_oldPlacement?: CalculatedPlacement;
 	_width?: string;
 	_height?: string;
+	_openerIntersectionObserver?: IntersectionObserver | null;
 
 	_popoverResize: PopoverResize;
 
@@ -290,11 +291,14 @@ class Popover extends Popup {
 		this._initialHeight = this.style.height;
 
 		this._openerRect = opener.getBoundingClientRect();
+		this._observeOpenerVisibility();
 
 		await super.openPopup();
 	}
 
 	closePopup(escPressed = false, preventRegistryUpdate = false, preventFocusRestore = false) : void {
+		this._unobserveOpenerVisibility();
+
 		Object.assign(this.style, {
 			width: this._initialWidth,
 			height: this._initialHeight,
@@ -363,6 +367,10 @@ class Popover extends Popup {
 
 		let rootNode = this.getRootNode();
 
+		if (!rootNode) {
+			return null;
+		}
+
 		if (rootNode === this) {
 			rootNode = document;
 		}
@@ -550,6 +558,49 @@ class Popover extends Popup {
 		return top + (Number.parseInt(this.style.top || "0") - actualTop);
 	}
 
+	/**
+	 * Callback invoked when the opener element's intersection changes.
+	 * Closes popover when opener is out of view.
+	 * @private
+	 */
+	_onOpenerIntersection(entries: Array<IntersectionObserverEntry>): void {
+		if (this.open && !entries[0]?.isIntersecting) {
+			this.closePopup();
+		}
+	}
+
+	/**
+	 * Starts observing the opener element's visibility in the viewport.
+	 * @private
+	 */
+	_observeOpenerVisibility(): void {
+		this._unobserveOpenerVisibility();
+
+		const opener = this.getOpenerHTMLElement(this.opener);
+
+		if (!opener) {
+			return;
+		}
+
+		this._openerIntersectionObserver = new IntersectionObserver(
+			this._onOpenerIntersection.bind(this),
+			{ threshold: 0 },
+		);
+
+		this._openerIntersectionObserver.observe(opener);
+	}
+
+	/**
+	 * Stops observing and cleans up the IntersectionObserver.
+	 * @private
+	 */
+	_unobserveOpenerVisibility(): void {
+		if (this._openerIntersectionObserver) {
+			this._openerIntersectionObserver.disconnect();
+			this._openerIntersectionObserver = null;
+		}
+	}
+
 	getPopoverSize(calcScrollHeight: boolean = false): PopoverSize {
 		const rect = this.getBoundingClientRect();
 		const width = rect.width;
diff --git a/packages/main/test/pages/Popover.html b/packages/main/test/pages/Popover.html
index dbf1b8fec06c..1719e3d661a0 100644
--- a/packages/main/test/pages/Popover.html
+++ b/packages/main/test/pages/Popover.html
@@ -228,6 +228,21 @@
 			<ui5-button id="focusMe">Close</ui5-button>
 		</div>
 	</ui5-popover>
+	
+	<br>
+	<br>
+	<ui5-button id="closePopoverAfterScroll">Open popover and scroll</ui5-button>
+	<ui5-dialog id="scrollableDialog">
+		<div slot="header" style="height: 200px">LargeHeader</div>
+		<div style="height: 200px; overflow: auto">
+			<div style="height: 1000px">
+			<ui5-input value-state="Negative">
+				<span slot="valueStateMessage">Message</span>
+			</ui5-input>
+			</div>
+		</div>
+		<ui5-button slot="footer" id="closeAfterScrollBtn" design="Emphasized">Close</ui5-button>
+	</ui5-dialog>
 
 	<br>
 	<br>
@@ -747,6 +762,15 @@ <h3>Popover in ShadowRoot, Opener set as ID in window.document</h3>
 			document.getElementById("big-popover").open = true;
 		});
 
+		document.getElementById("closePopoverAfterScroll").addEventListener("click", function (event) {
+			scrollableDialog.opener = event.target;
+			scrollableDialog.open = true;
+		});
+
+		document.getElementById("closeAfterScrollBtn").addEventListener("click", function (event) {
+			scrollableDialog.open = false;
+		});
+
 		document.getElementById("acc-role-popover-button").addEventListener("click", function (event) {
 			document.getElementById("acc-role-popover").opener = event.target;
 			document.getElementById("acc-role-popover").open = true;