diff --git a/Modules/makesetup b/Modules/makesetup
index 586e26dd5891b0..bd33c8fb2804c7 100755
--- a/Modules/makesetup
+++ b/Modules/makesetup
@@ -282,7 +282,7 @@ sed -e 's/[ 	]*#.*//' -e '/^[ 	]*$/d' |
 			# there's actually only one obj, so just set it to the lib
 			for lib in $libs
 			do
-				objs="target/\$(CARGO_TARGET_DIR)/$lib"
+				objs="target/\$(if \$(CARGO_TARGET),\$(CARGO_TARGET)/\$(CARGO_TARGET_DIR),\$(CARGO_TARGET_DIR))/$lib"
 			done
 			libs=
 			# depends on the headers through cpython-sys
diff --git a/configure b/configure
index 8af7ee0e042e81..98175608ffa45a 100755
--- a/configure
+++ b/configure
@@ -16110,6 +16110,15 @@ else
     aarch64-apple-ios-simulator)
       CARGO_TARGET="aarch64-apple-ios-sim"
       ;;
+    *-apple-darwin*)
+      cargo_host="$host"
+      case "$cargo_host" in
+        arm64-apple-*)
+          cargo_host="aarch64${cargo_host#arm64}"
+          ;;
+      esac
+      CARGO_TARGET="${cargo_host%%-apple-darwin*}-apple-darwin"
+      ;;
     *)
       CARGO_TARGET="$host"
       ;;
@@ -36175,4 +36184,3 @@ if test "$ac_cv_header_stdatomic_h" != "yes"; then
   { printf "%s\n" "$as_me:${as_lineno-$LINENO}: Your compiler or platform does have a working C11 stdatomic.h. A future version of Python may require stdatomic.h." >&5
 printf "%s\n" "$as_me: Your compiler or platform does have a working C11 stdatomic.h. A future version of Python may require stdatomic.h." >&6;}
 fi
-
diff --git a/configure.ac b/configure.ac
index a3cc99c8add8c3..91633ebbf342ae 100644
--- a/configure.ac
+++ b/configure.ac
@@ -4333,6 +4333,15 @@ else
     aarch64-apple-ios-simulator)
       CARGO_TARGET="aarch64-apple-ios-sim"
       ;;
+    *-apple-darwin*)
+      cargo_host="$host"
+      case "$cargo_host" in
+        arm64-apple-*)
+          cargo_host="aarch64${cargo_host#arm64}"
+          ;;
+      esac
+      CARGO_TARGET="${cargo_host%%-apple-darwin*}-apple-darwin"
+      ;;
     *)
       CARGO_TARGET="$host"
       ;;