diff --git a/.github/workflows/simulate.yml b/.github/workflows/simulate.yml index f8346e6..40e6ce6 100644 --- a/.github/workflows/simulate.yml +++ b/.github/workflows/simulate.yml @@ -3,6 +3,13 @@ on: push: branches: - master + pull_request: + paths: + - 'problems/**' + - 'src/python/simulate.py' + - 'src/python/solver_settings.yaml' + - 'src/python/benchmark_models_petab/**' + - '.github/workflows/simulate.yml' workflow_dispatch: merge_group: schedule: @@ -25,17 +32,26 @@ jobs: AMICI_PARALLEL_COMPILE: "" run: | pip install --upgrade pip - # TODO: once amici 1.0 is released, replace with: - # pip install amici[petab] - pip install petab - pip install "git+https://github.com/dweindl/amici.git@6a85422ad233fc268fb71272bba39f5b82db387a#egg=amici&subdirectory=python/sdist" + pip install "amici[petab]>=1.2.0" - - name: Simulate with nominal parameters + - name: Simulate and compare to the simulation tables env: AMICI_PARALLEL_COMPILE: "" + # The problems are simulated with the solver settings of + # src/python/solver_settings.yaml. run: | + failed=() for problem in `ls -1 problems/`; do - python src/python/simulate.py "$problem" -j + python src/python/simulate.py "$problem" -j --check-simulations \ + || failed+=("$problem") echo echo done + + { + echo "### Comparison to the simulation tables" + echo + echo "Failed: ${failed[*]:-none}" + } | tee -a "$GITHUB_STEP_SUMMARY" + + [ ${#failed[@]} -eq 0 ] diff --git a/CONTRIBUTING.md b/CONTRIBUTING.md index 594c32f..60d338f 100644 --- a/CONTRIBUTING.md +++ b/CONTRIBUTING.md @@ -4,8 +4,9 @@ Simply create a new branch and open a pull request with your files. We will then Each problem lives under `problems//`, with at least one of `v1/`/`v2/` present: - `v1/` holds the problem in PEtab v1 format: `problem.yaml`, `model.xml`, - `conditions.tsv`, `measurements.tsv`, `observables.tsv`, `parameters.tsv`, and optionally - `simulations.tsv` and `visualizations.tsv`. + `conditions.tsv`, `measurements.tsv`, `observables.tsv`, `parameters.tsv`, + `simulations.tsv` (see [Simulation table](#simulation-table)), and optionally + `visualizations.tsv`. - `v2/` holds the same problem in PEtab v2 format. - `metadata.yaml` contains version-independent metadata. Currently, this is a single-sentence `short_description` of the problem, stating the type of model (e.g., biochemical reaction network, @@ -22,6 +23,20 @@ Each problem lives under `problems//`, with at least one of `v1/`/`v2 PEtab files themselves (e.g. raw data, scripts, notebooks, figures). There's no prescribed structure — organize it however fits your problem. +## Simulation table + +`v1/simulations.tsv` holds the simulations of the model at the nominal parameters of the +parameter table, one row per row of the measurement table: the measurement table with the +column `measurement` replaced by `simulation`. It can be generated with AMICI: +```bash +python src/python/simulate.py --output problems//v1/simulations.tsv +``` +The [Simulate](.github/workflows/simulate.yml) workflow checks that every problem reproduces +its simulation table (`simulate.py --check-simulations`), with the solver settings +of [`solver_settings.yaml`](src/python/solver_settings.yaml). Check that these settings are +accurate enough for a new problem with `simulate.py --check-simulation-tolerances`, +and add problem-specific settings to `solver_settings.yaml` if they are not. + ## v1/v2 equivalence A problem's `v1/` and `v2/` encodings must represent *exactly* the same mathematical problem: diff --git a/problems/Blasi_CellSystems2016/v1/simulations.tsv b/problems/Blasi_CellSystems2016/v1/simulations.tsv index 8fd4f78..b6071e6 100644 --- a/problems/Blasi_CellSystems2016/v1/simulations.tsv +++ b/problems/Blasi_CellSystems2016/v1/simulations.tsv @@ -119,33 +119,6 @@ observable_k5k12 control 0.047962399802456 inf sigma observable_k5k12 control 0.047962399802456 inf sigma observable_k5k12 control 0.047962399802456 inf sigma observable_k5k12 control 0.047962399802456 inf sigma -observable_k5k12 control 0.047962399802456 inf sigma -observable_k5k12 control 0.047962399802456 inf sigma -observable_k5k12 control 0.047962399802456 inf sigma -observable_k5k12 control 0.047962399802456 inf sigma -observable_k5k12 control 0.047962399802456 inf sigma -observable_k5k12 control 0.047962399802456 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k5k16 control 0.003900604877395 inf sigma -observable_k8k12 control 0.007670374014446 inf sigma -observable_k8k12 control 0.007670374014446 inf sigma -observable_k8k12 control 0.007670374014446 inf sigma observable_k8k12 control 0.007670374014446 inf sigma observable_k8k12 control 0.007670374014446 inf sigma observable_k8k12 control 0.007670374014446 inf sigma @@ -158,15 +131,6 @@ observable_k8k12 control 0.007670374014446 inf sigma observable_k8k12 control 0.007670374014446 inf sigma observable_k8k12 control 0.007670374014446 inf sigma observable_k8k12 control 0.007670374014446 inf sigma -observable_k8k12 control 0.007670374014446 inf sigma -observable_k8k12 control 0.007670374014446 inf sigma -observable_k8k12 control 0.007670374014446 inf sigma -observable_k8k16 control 0.004314605919164 inf sigma -observable_k8k16 control 0.004314605919164 inf sigma -observable_k8k16 control 0.004314605919164 inf sigma -observable_k8k16 control 0.004314605919164 inf sigma -observable_k8k16 control 0.004314605919164 inf sigma -observable_k8k16 control 0.004314605919164 inf sigma observable_k8k16 control 0.004314605919164 inf sigma observable_k8k16 control 0.004314605919164 inf sigma observable_k8k16 control 0.004314605919164 inf sigma diff --git a/problems/Chen_MSB2009/v1/simulations.tsv b/problems/Chen_MSB2009/v1/simulations.tsv index c0fa78f..3db042e 100644 --- a/problems/Chen_MSB2009/v1/simulations.tsv +++ b/problems/Chen_MSB2009/v1/simulations.tsv @@ -1,121 +1,121 @@ observableId preequilibrationConditionId simulationConditionId simulation time observableParameters noiseParameters datasetId -ERB_B1_P_tot model1_data1 8.88387621921431E-13 1800 EGFR_t 0.1 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 43.5718043105709 1950 EGFR_t 7.4 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 52.1145985039882 2100 EGFR_t 6.8 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 55.7486613742705 2250 EGFR_t 8.9 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 57.8091974066766 2400 EGFR_t 4.7 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 60.0885250712489 2700 EGFR_t 4.7 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 62.5599123936139 3600 EGFR_t 2.5 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 63.3375379783163 4500 EGFR_t 2.4 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 63.6475120605309 5400 EGFR_t 13.1 model1_data1_ERB_B1_P_tot -ERB_B1_P_tot model1_data1 63.657723259226 9000 EGFR_t 13.1 model1_data1_ERB_B1_P_tot -ERK_PP model1_data1 2.52423312491575E-11 1800 ERK_t 0.1 model1_data1_ERK_PP -ERK_PP model1_data1 69.3855801236379 1950 ERK_t 0.46 model1_data1_ERK_PP -ERK_PP model1_data1 69.0806370662617 2100 ERK_t 1.9 model1_data1_ERK_PP -ERK_PP model1_data1 67.3562315614362 2250 ERK_t 1.5 model1_data1_ERK_PP -ERK_PP model1_data1 65.4726536397062 2400 ERK_t 1.2 model1_data1_ERK_PP -ERK_PP model1_data1 61.7105809137709 2700 ERK_t 3.1 model1_data1_ERK_PP -ERK_PP model1_data1 52.1279030059724 3600 ERK_t 2.8 model1_data1_ERK_PP -ERK_PP model1_data1 45.3081820299199 4500 ERK_t 2.9 model1_data1_ERK_PP -ERK_PP model1_data1 40.6661974926109 5400 ERK_t 3.7 model1_data1_ERK_PP -ERK_PP model1_data1 33.747577355144 9000 ERK_t 1.5 model1_data1_ERK_PP -AKT_PP model1_data1 5.29862853957213E-52 1800 AKT_t 0.1 model1_data1_AKT_PP -AKT_PP model1_data1 46.9128475628656 1950 AKT_t 0.1 model1_data1_AKT_PP -AKT_PP model1_data1 49.3644152750207 2100 AKT_t 0.36 model1_data1_AKT_PP -AKT_PP model1_data1 50.0708103111029 2250 AKT_t 0.69 model1_data1_AKT_PP -AKT_PP model1_data1 50.2875849549111 2400 AKT_t 2.3 model1_data1_AKT_PP -AKT_PP model1_data1 50.2843567254821 2700 AKT_t 2.1 model1_data1_AKT_PP -AKT_PP model1_data1 49.8232571479622 3600 AKT_t 1.5 model1_data1_AKT_PP -AKT_PP model1_data1 49.3838023306466 4500 AKT_t 3.5 model1_data1_AKT_PP -AKT_PP model1_data1 48.9860095764 5400 AKT_t 2.3 model1_data1_AKT_PP -AKT_PP model1_data1 47.5709579212551 9000 AKT_t 7.4 model1_data1_AKT_PP -ERB_B1_P_tot model1_data2 3.36363329625249E-17 1800 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.000528876163967 1950 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.000498882602886 2100 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.000466345782826 2250 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.00045884216035 2400 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.000465416745889 2700 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.000500321469747 3600 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.000534193225367 4500 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.000566166733081 5400 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERB_B1_P_tot model1_data2 0.000675558959884 9000 EGFR_t 0.1 model1_data2_ERB_B1_P_tot -ERK_PP model1_data2 5.00383145707368E-154 1800 ERK_t 0.1 model1_data2_ERK_PP -ERK_PP model1_data2 24.262444854452 1950 ERK_t 3.4 model1_data2_ERK_PP -ERK_PP model1_data2 31.9517037134021 2100 ERK_t 6.8 model1_data2_ERK_PP -ERK_PP model1_data2 32.6244225748506 2250 ERK_t 1.9 model1_data2_ERK_PP -ERK_PP model1_data2 31.7682524046738 2400 ERK_t 4 model1_data2_ERK_PP -ERK_PP model1_data2 28.6759620505581 2700 ERK_t 4.3 model1_data2_ERK_PP -ERK_PP model1_data2 21.2022643602703 3600 ERK_t 2.7 model1_data2_ERK_PP -ERK_PP model1_data2 17.8628027432288 4500 ERK_t 1.2 model1_data2_ERK_PP -ERK_PP model1_data2 16.5580541395666 5400 ERK_t 0.94 model1_data2_ERK_PP -ERK_PP model1_data2 15.8181136826053 9000 ERK_t 2.3 model1_data2_ERK_PP -AKT_PP model1_data2 5.08139567615343E-76 1800 AKT_t 0.1 model1_data2_AKT_PP -AKT_PP model1_data2 56.035388130668 1950 AKT_t 4.7 model1_data2_AKT_PP -AKT_PP model1_data2 69.4880500801865 2100 AKT_t 3.2 model1_data2_AKT_PP -AKT_PP model1_data2 73.4248062028344 2250 AKT_t 4.6 model1_data2_AKT_PP -AKT_PP model1_data2 74.2439422655282 2400 AKT_t 3.2 model1_data2_AKT_PP -AKT_PP model1_data2 73.7648085482688 2700 AKT_t 2.9 model1_data2_AKT_PP -AKT_PP model1_data2 69.4182443713225 3600 AKT_t 2.8 model1_data2_AKT_PP -AKT_PP model1_data2 64.8617703174951 4500 AKT_t 2.6 model1_data2_AKT_PP -AKT_PP model1_data2 61.2321756306954 5400 AKT_t 1.8 model1_data2_AKT_PP -AKT_PP model1_data2 52.0027923944557 9000 AKT_t 2.3 model1_data2_AKT_PP -ERB_B1_P_tot model1_data3 1.76775554783494E-15 1800 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.036418682306522 1950 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.038141189649734 2100 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.037788264080809 2250 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.037891012706382 2400 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.038998169813646 2700 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.04291752099434 3600 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.045741898484001 4500 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.047697723787962 5400 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERB_B1_P_tot model1_data3 0.051140032777417 9000 EGFR_t 0.1 model1_data3_ERB_B1_P_tot -ERK_PP model1_data3 4.05689429468581E-22 1800 ERK_t 0.1 model1_data3_ERK_PP -ERK_PP model1_data3 19.1283412548992 1950 ERK_t 3.4 model1_data3_ERK_PP -ERK_PP model1_data3 29.0262991158362 2100 ERK_t 6.8 model1_data3_ERK_PP -ERK_PP model1_data3 29.3496850233104 2250 ERK_t 1.9 model1_data3_ERK_PP -ERK_PP model1_data3 28.3669494838099 2400 ERK_t 4 model1_data3_ERK_PP -ERK_PP model1_data3 25.2944505933136 2700 ERK_t 4.3 model1_data3_ERK_PP -ERK_PP model1_data3 18.3269400330114 3600 ERK_t 2.7 model1_data3_ERK_PP -ERK_PP model1_data3 15.5414077429536 4500 ERK_t 1.2 model1_data3_ERK_PP -ERK_PP model1_data3 14.5840346873173 5400 ERK_t 0.94 model1_data3_ERK_PP -ERK_PP model1_data3 14.1306270404719 9000 ERK_t 2.3 model1_data3_ERK_PP -AKT_PP model1_data3 8.49071717018033E-63 1800 AKT_t 0.1 model1_data3_AKT_PP -AKT_PP model1_data3 0.001239915893444 1950 AKT_t 0.98 model1_data3_AKT_PP -AKT_PP model1_data3 33.7142067464579 2100 AKT_t 11.1 model1_data3_AKT_PP -AKT_PP model1_data3 43.9127707791346 2250 AKT_t 5.6 model1_data3_AKT_PP -AKT_PP model1_data3 46.3374858930585 2400 AKT_t 3.1 model1_data3_AKT_PP -AKT_PP model1_data3 48.2386429805479 2700 AKT_t 4.5 model1_data3_AKT_PP -AKT_PP model1_data3 49.1448803968136 3600 AKT_t 5.1 model1_data3_AKT_PP -AKT_PP model1_data3 49.1112264321989 4500 AKT_t 14.1 model1_data3_AKT_PP -AKT_PP model1_data3 48.9883910876766 5400 AKT_t 9.7 model1_data3_AKT_PP -AKT_PP model1_data3 48.435645908212 9000 AKT_t 5.6 model1_data3_AKT_PP -ERB_B1_P_tot model1_data4 6.7277291085564E-19 1800 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 2.92689710183634E-05 1950 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 3.28578777243557E-05 2100 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 3.10986842926543E-05 2250 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 3.02366245604384E-05 2400 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 3.00182582173071E-05 2700 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 3.08359536201293E-05 3600 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 3.20124467350121E-05 4500 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 3.34324595680437E-05 5400 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERB_B1_P_tot model1_data4 4.00121953425809E-05 9000 EGFR_t 0.1 model1_data4_ERB_B1_P_tot -ERK_PP model1_data4 8.64657840082615E-161 1800 ERK_t 0.1 model1_data4_ERK_PP -ERK_PP model1_data4 11.8508078706432 1950 ERK_t 4.3 model1_data4_ERK_PP -ERK_PP model1_data4 24.0162664665207 2100 ERK_t 1.1 model1_data4_ERK_PP -ERK_PP model1_data4 22.909537519056 2250 ERK_t 8.2 model1_data4_ERK_PP -ERK_PP model1_data4 21.5370745078285 2400 ERK_t 4.7 model1_data4_ERK_PP -ERK_PP model1_data4 18.5449419468594 2700 ERK_t 1.5 model1_data4_ERK_PP -ERK_PP model1_data4 13.1420907480741 3600 ERK_t 1.04 model1_data4_ERK_PP -ERK_PP model1_data4 11.6246110790524 4500 ERK_t 1.7 model1_data4_ERK_PP -ERK_PP model1_data4 11.2663102442266 5400 ERK_t 3 model1_data4_ERK_PP -ERK_PP model1_data4 11.1857483428179 9000 ERK_t 2.2 model1_data4_ERK_PP -AKT_PP model1_data4 2.07871827222141E-79 1800 AKT_t 0.1 model1_data4_AKT_PP -AKT_PP model1_data4 17.7717537002553 1950 AKT_t 0.1 model1_data4_AKT_PP -AKT_PP model1_data4 49.7843830516816 2100 AKT_t 4.6 model1_data4_AKT_PP -AKT_PP model1_data4 54.3919048297901 2250 AKT_t 7.7 model1_data4_AKT_PP -AKT_PP model1_data4 57.4195216254196 2400 AKT_t 3.6 model1_data4_AKT_PP -AKT_PP model1_data4 61.3070244609459 2700 AKT_t 3.6 model1_data4_AKT_PP -AKT_PP model1_data4 66.701230177369 3600 AKT_t 1.6 model1_data4_AKT_PP -AKT_PP model1_data4 68.5874591917684 4500 AKT_t 13.1 model1_data4_AKT_PP -AKT_PP model1_data4 69.0198350686646 5400 AKT_t 13.1 model1_data4_AKT_PP -AKT_PP model1_data4 65.4734800728311 9000 AKT_t 12.1 model1_data4_AKT_PP +ERB_B1_P_tot model1_data1 8.892604268871969e-13 1800 EGFR_t 0.1 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 43.56293875943254 1950 EGFR_t 7.4 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 52.108038877229454 2100 EGFR_t 6.8 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 55.743490145306616 2250 EGFR_t 8.9 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 57.80496564853609 2400 EGFR_t 4.7 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 60.085503910614186 2700 EGFR_t 4.7 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 62.55847969642451 3600 EGFR_t 2.5 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 63.33670411336011 4500 EGFR_t 2.4 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 63.64697250987766 5400 EGFR_t 13.1 model1_data1_ERB_B1_P_tot +ERB_B1_P_tot model1_data1 63.65755811542504 9000 EGFR_t 13.1 model1_data1_ERB_B1_P_tot +ERK_PP model1_data1 2.522197191558486e-11 1800 ERK_t 0.1 model1_data1_ERK_PP +ERK_PP model1_data1 69.38590012576795 1950 ERK_t 0.46 model1_data1_ERK_PP +ERK_PP model1_data1 69.07866716910523 2100 ERK_t 1.9 model1_data1_ERK_PP +ERK_PP model1_data1 67.35273556242697 2250 ERK_t 1.5 model1_data1_ERK_PP +ERK_PP model1_data1 65.46915381276472 2400 ERK_t 1.2 model1_data1_ERK_PP +ERK_PP model1_data1 61.70708586597013 2700 ERK_t 3.1 model1_data1_ERK_PP +ERK_PP model1_data1 52.124513703361195 3600 ERK_t 2.8 model1_data1_ERK_PP +ERK_PP model1_data1 45.30501930271374 4500 ERK_t 2.9 model1_data1_ERK_PP +ERK_PP model1_data1 40.66331184725359 5400 ERK_t 3.7 model1_data1_ERK_PP +ERK_PP model1_data1 33.745507025195394 9000 ERK_t 1.5 model1_data1_ERK_PP +AKT_PP model1_data1 5.312840217687943e-52 1800 AKT_t 0.1 model1_data1_AKT_PP +AKT_PP model1_data1 46.91473763326338 1950 AKT_t 0.1 model1_data1_AKT_PP +AKT_PP model1_data1 49.36855197481459 2100 AKT_t 0.36 model1_data1_AKT_PP +AKT_PP model1_data1 50.07554806799437 2250 AKT_t 0.69 model1_data1_AKT_PP +AKT_PP model1_data1 50.292545982571006 2400 AKT_t 2.3 model1_data1_AKT_PP +AKT_PP model1_data1 50.289456657531744 2700 AKT_t 2.1 model1_data1_AKT_PP +AKT_PP model1_data1 49.82845276992091 3600 AKT_t 1.5 model1_data1_AKT_PP +AKT_PP model1_data1 49.389084248734385 4500 AKT_t 3.5 model1_data1_AKT_PP +AKT_PP model1_data1 48.991388034021476 5400 AKT_t 2.3 model1_data1_AKT_PP +AKT_PP model1_data1 47.57680613048939 9000 AKT_t 7.4 model1_data1_AKT_PP +ERB_B1_P_tot model1_data2 3.366255712391295e-17 1800 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.0005294224345498631 1950 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.0004992308198830339 2100 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.0004665698179407662 2250 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.00045902698214301207 2400 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.0004655952949649424 2700 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.0005005349352257308 3600 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.0005344421171389572 4500 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.0005664482806379632 5400 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERB_B1_P_tot model1_data2 0.0006759407648655859 9000 EGFR_t 0.1 model1_data2_ERB_B1_P_tot +ERK_PP model1_data2 4.215351675657515e-154 1800 ERK_t 0.1 model1_data2_ERK_PP +ERK_PP model1_data2 24.26494331235108 1950 ERK_t 3.4 model1_data2_ERK_PP +ERK_PP model1_data2 31.968381846437698 2100 ERK_t 6.8 model1_data2_ERK_PP +ERK_PP model1_data2 32.648159533535974 2250 ERK_t 1.9 model1_data2_ERK_PP +ERK_PP model1_data2 31.795214790269952 2400 ERK_t 4 model1_data2_ERK_PP +ERK_PP model1_data2 28.705015875997407 2700 ERK_t 4.3 model1_data2_ERK_PP +ERK_PP model1_data2 21.22860314787617 3600 ERK_t 2.7 model1_data2_ERK_PP +ERK_PP model1_data2 17.88444770879005 4500 ERK_t 1.2 model1_data2_ERK_PP +ERK_PP model1_data2 16.57647624817953 5400 ERK_t 0.94 model1_data2_ERK_PP +ERK_PP model1_data2 15.833577663570386 9000 ERK_t 2.3 model1_data2_ERK_PP +AKT_PP model1_data2 4.894858924333466e-76 1800 AKT_t 0.1 model1_data2_AKT_PP +AKT_PP model1_data2 56.024856472067455 1950 AKT_t 4.7 model1_data2_AKT_PP +AKT_PP model1_data2 69.4793281351895 2100 AKT_t 3.2 model1_data2_AKT_PP +AKT_PP model1_data2 73.4205919120399 2250 AKT_t 4.6 model1_data2_AKT_PP +AKT_PP model1_data2 74.24142426731191 2400 AKT_t 3.2 model1_data2_AKT_PP +AKT_PP model1_data2 73.76260119447403 2700 AKT_t 2.9 model1_data2_AKT_PP +AKT_PP model1_data2 69.41056996100741 3600 AKT_t 2.8 model1_data2_AKT_PP +AKT_PP model1_data2 64.84920709284943 4500 AKT_t 2.6 model1_data2_AKT_PP +AKT_PP model1_data2 61.217996882470395 5400 AKT_t 1.8 model1_data2_AKT_PP +AKT_PP model1_data2 51.98737532495822 9000 AKT_t 2.3 model1_data2_AKT_PP +ERB_B1_P_tot model1_data3 1.769497743313006e-15 1800 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.03640205812427815 1950 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.03812816179877623 2100 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.037774710559037715 2250 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.037877708030551314 2400 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.03898677739640392 2700 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.0429128723043843 3600 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.04574371935685564 4500 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.047704883246949596 5400 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERB_B1_P_tot model1_data3 0.05115885460320347 9000 EGFR_t 0.1 model1_data3_ERB_B1_P_tot +ERK_PP model1_data3 4.0536284679277516e-22 1800 ERK_t 0.1 model1_data3_ERK_PP +ERK_PP model1_data3 19.127380897824636 1950 ERK_t 3.4 model1_data3_ERK_PP +ERK_PP model1_data3 29.03913887686807 2100 ERK_t 6.8 model1_data3_ERK_PP +ERK_PP model1_data3 29.368735900640754 2250 ERK_t 1.9 model1_data3_ERK_PP +ERK_PP model1_data3 28.388393649297168 2400 ERK_t 4 model1_data3_ERK_PP +ERK_PP model1_data3 25.31731817490675 2700 ERK_t 4.3 model1_data3_ERK_PP +ERK_PP model1_data3 18.347224966362845 3600 ERK_t 2.7 model1_data3_ERK_PP +ERK_PP model1_data3 15.557754293986864 4500 ERK_t 1.2 model1_data3_ERK_PP +ERK_PP model1_data3 14.598026344589075 5400 ERK_t 0.94 model1_data3_ERK_PP +ERK_PP model1_data3 14.14286262615827 9000 ERK_t 2.3 model1_data3_ERK_PP +AKT_PP model1_data3 8.512172967414222e-63 1800 AKT_t 0.1 model1_data3_AKT_PP +AKT_PP model1_data3 0.0012396529260216259 1950 AKT_t 0.98 model1_data3_AKT_PP +AKT_PP model1_data3 33.72004274935501 2100 AKT_t 11.1 model1_data3_AKT_PP +AKT_PP model1_data3 43.915446808940914 2250 AKT_t 5.6 model1_data3_AKT_PP +AKT_PP model1_data3 46.34004065549584 2400 AKT_t 3.1 model1_data3_AKT_PP +AKT_PP model1_data3 48.24117005631464 2700 AKT_t 4.5 model1_data3_AKT_PP +AKT_PP model1_data3 49.14740864588404 3600 AKT_t 5.1 model1_data3_AKT_PP +AKT_PP model1_data3 49.11369596555675 4500 AKT_t 14.1 model1_data3_AKT_PP +AKT_PP model1_data3 48.99076400898571 5400 AKT_t 9.7 model1_data3_AKT_PP +AKT_PP model1_data3 48.43758984152925 9000 AKT_t 5.6 model1_data3_AKT_PP +ERB_B1_P_tot model1_data4 6.732996976792516e-19 1800 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 2.9300641824803998e-05 1950 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 3.2884377119516325e-05 2100 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 3.111663452381221e-05 2250 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 3.0250957284763296e-05 2400 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 3.00310187952186e-05 2700 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 3.084901392585651e-05 3600 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 3.202629012485375e-05 4500 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 3.3447316197439644e-05 5400 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERB_B1_P_tot model1_data4 4.003213251164999e-05 9000 EGFR_t 0.1 model1_data4_ERB_B1_P_tot +ERK_PP model1_data4 6.751355650259865e-161 1800 ERK_t 0.1 model1_data4_ERK_PP +ERK_PP model1_data4 11.841831604746883 1950 ERK_t 4.3 model1_data4_ERK_PP +ERK_PP model1_data4 24.01366152096423 2100 ERK_t 1.1 model1_data4_ERK_PP +ERK_PP model1_data4 22.908180034831688 2250 ERK_t 8.2 model1_data4_ERK_PP +ERK_PP model1_data4 21.53656989960601 2400 ERK_t 4.7 model1_data4_ERK_PP +ERK_PP model1_data4 18.54554691706006 2700 ERK_t 1.5 model1_data4_ERK_PP +ERK_PP model1_data4 13.143797448269764 3600 ERK_t 1.04 model1_data4_ERK_PP +ERK_PP model1_data4 11.626444587272141 4500 ERK_t 1.7 model1_data4_ERK_PP +ERK_PP model1_data4 11.26819803399853 5400 ERK_t 3 model1_data4_ERK_PP +ERK_PP model1_data4 11.187798401906864 9000 ERK_t 2.2 model1_data4_ERK_PP +AKT_PP model1_data4 1.9582007003665646e-79 1800 AKT_t 0.1 model1_data4_AKT_PP +AKT_PP model1_data4 17.722759617608318 1950 AKT_t 0.1 model1_data4_AKT_PP +AKT_PP model1_data4 49.77856316753892 2100 AKT_t 4.6 model1_data4_AKT_PP +AKT_PP model1_data4 54.386515373285384 2250 AKT_t 7.7 model1_data4_AKT_PP +AKT_PP model1_data4 57.41423151545343 2400 AKT_t 3.6 model1_data4_AKT_PP +AKT_PP model1_data4 61.3017545460959 2700 AKT_t 3.6 model1_data4_AKT_PP +AKT_PP model1_data4 66.69639690291952 3600 AKT_t 1.6 model1_data4_AKT_PP +AKT_PP model1_data4 68.58345923886567 4500 AKT_t 13.1 model1_data4_AKT_PP +AKT_PP model1_data4 69.01652510128231 5400 AKT_t 13.1 model1_data4_AKT_PP +AKT_PP model1_data4 65.47238257549402 9000 AKT_t 12.1 model1_data4_AKT_PP diff --git a/problems/Fujita_SciSignal2010/v1/simulations.tsv b/problems/Fujita_SciSignal2010/v1/simulations.tsv index 3e7fba5..a69e94f 100644 --- a/problems/Fujita_SciSignal2010/v1/simulations.tsv +++ b/problems/Fujita_SciSignal2010/v1/simulations.tsv @@ -1,145 +1,145 @@ observableId preequilibrationConditionId simulationConditionId simulation time observableParameters noiseParameters observableTransformation datasetId -pEGFR_tot model1_data1 0 0 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot -pEGFR_tot model1_data1 0.012441876 60 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot -pEGFR_tot model1_data1 0.0187120065 120 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot -pEGFR_tot model1_data1 0.0158168482 300 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot -pEGFR_tot model1_data1 0.0092928584 600 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot -pEGFR_tot model1_data1 0.0054601697 900 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot -pEGFR_tot model1_data1 0.0011396679 1800 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot -pEGFR_tot model1_data1 0.0001018308 3600 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot -pAkt_tot model1_data1 0 0 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot -pAkt_tot model1_data1 0.0355108621 60 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot -pAkt_tot model1_data1 0.1053412851 120 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot -pAkt_tot model1_data1 0.167356844 300 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot -pAkt_tot model1_data1 0.1359909071 600 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot -pAkt_tot model1_data1 0.1071886841 900 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot -pAkt_tot model1_data1 0.0605225951 1800 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot -pAkt_tot model1_data1 0.0276204035 3600 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot -pS6_tot model1_data1 0 0 scaling_pS6_tot 0.01 lin model1_data1_pS6_tot -pS6_tot model1_data1 5.78895984805857E-05 60 scaling_pS6_tot 0.01 lin model1_data1_pS6_tot -pS6_tot model1_data1 0.0009531255 120 scaling_pS6_tot 0.01 lin model1_data1_pS6_tot -pS6_tot model1_data1 0.0185497283 300 scaling_pS6_tot 0.01 lin model1_data1_pS6_tot -pS6_tot model1_data1 0.0927501675 600 scaling_pS6_tot 0.02 lin model1_data1_pS6_tot -pS6_tot model1_data1 0.1859892615 900 scaling_pS6_tot 0.02 lin model1_data1_pS6_tot -pS6_tot model1_data1 0.3842285889 1800 scaling_pS6_tot 0.035 lin model1_data1_pS6_tot -pS6_tot model1_data1 0.3671651134 3600 scaling_pS6_tot 0.035 lin model1_data1_pS6_tot -pEGFR_tot model1_data2 0 0 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot -pEGFR_tot model1_data2 0.0366295138 60 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot -pEGFR_tot model1_data2 0.0536154835 120 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot -pEGFR_tot model1_data2 0.0405530546 300 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot -pEGFR_tot model1_data2 0.0194943054 600 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot -pEGFR_tot model1_data2 0.0093857599 900 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot -pEGFR_tot model1_data2 0.001138775 1800 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot -pEGFR_tot model1_data2 0.0001393242 3600 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot -pAkt_tot model1_data2 0 0 scaling_pAkt_tot 0.01 lin model1_data2_pAkt_tot -pAkt_tot model1_data2 0.1010762041 60 scaling_pAkt_tot 0.01 lin model1_data2_pAkt_tot -pAkt_tot model1_data2 0.2711737267 120 scaling_pAkt_tot 0.03 lin model1_data2_pAkt_tot -pAkt_tot model1_data2 0.3607036934 300 scaling_pAkt_tot 0.01 lin model1_data2_pAkt_tot -pAkt_tot model1_data2 0.2663746843 600 scaling_pAkt_tot 0.02 lin model1_data2_pAkt_tot -pAkt_tot model1_data2 0.1952487389 900 scaling_pAkt_tot 0.02 lin model1_data2_pAkt_tot -pAkt_tot model1_data2 0.1006842668 1800 scaling_pAkt_tot 0.02 lin model1_data2_pAkt_tot -pAkt_tot model1_data2 0.0474357736 3600 scaling_pAkt_tot 0.01 lin model1_data2_pAkt_tot -pS6_tot model1_data2 0 0 scaling_pS6_tot 0.01 lin model1_data2_pS6_tot -pS6_tot model1_data2 0.0001694707 60 scaling_pS6_tot 0.01 lin model1_data2_pS6_tot -pS6_tot model1_data2 0.0026563935 120 scaling_pS6_tot 0.01 lin model1_data2_pS6_tot -pS6_tot model1_data2 0.045833771 300 scaling_pS6_tot 0.01 lin model1_data2_pS6_tot -pS6_tot model1_data2 0.209607514 600 scaling_pS6_tot 0.02 lin model1_data2_pS6_tot -pS6_tot model1_data2 0.4007484657 900 scaling_pS6_tot 0.03 lin model1_data2_pS6_tot -pS6_tot model1_data2 0.7556316274 1800 scaling_pS6_tot 0.1 lin model1_data2_pS6_tot -pS6_tot model1_data2 0.6612775029 3600 scaling_pS6_tot 0.025 lin model1_data2_pS6_tot -pEGFR_tot model1_data3 0 0 scaling_pEGFR_tot 0.01 lin model1_data3_pEGFR_tot -pEGFR_tot model1_data3 0.1144234645 60 scaling_pEGFR_tot 0.05 lin model1_data3_pEGFR_tot -pEGFR_tot model1_data3 0.1527713319 120 scaling_pEGFR_tot 0.025 lin model1_data3_pEGFR_tot -pEGFR_tot model1_data3 0.0790765114 300 scaling_pEGFR_tot 0.065 lin model1_data3_pEGFR_tot -pEGFR_tot model1_data3 0.0190585422 600 scaling_pEGFR_tot 0.025 lin model1_data3_pEGFR_tot -pEGFR_tot model1_data3 0.0047011183 900 scaling_pEGFR_tot 0.02 lin model1_data3_pEGFR_tot -pEGFR_tot model1_data3 0.0002765524 1800 scaling_pEGFR_tot 0.01 lin model1_data3_pEGFR_tot -pEGFR_tot model1_data3 0.0002160785 3600 scaling_pEGFR_tot 0.01 lin model1_data3_pEGFR_tot -pAkt_tot model1_data3 0 0 scaling_pAkt_tot 0.01 lin model1_data3_pAkt_tot -pAkt_tot model1_data3 0.2842569939 60 scaling_pAkt_tot 0.1 lin model1_data3_pAkt_tot -pAkt_tot model1_data3 0.5853547296 120 scaling_pAkt_tot 0.07 lin model1_data3_pAkt_tot -pAkt_tot model1_data3 0.5688099515 300 scaling_pAkt_tot 0.03 lin model1_data3_pAkt_tot -pAkt_tot model1_data3 0.3263752664 600 scaling_pAkt_tot 0.03 lin model1_data3_pAkt_tot -pAkt_tot model1_data3 0.1969268998 900 scaling_pAkt_tot 0.03 lin model1_data3_pAkt_tot -pAkt_tot model1_data3 0.1059534913 1800 scaling_pAkt_tot 0.02 lin model1_data3_pAkt_tot -pAkt_tot model1_data3 0.0547391878 3600 scaling_pAkt_tot 0.01 lin model1_data3_pAkt_tot -pS6_tot model1_data3 0 0 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot -pS6_tot model1_data3 0.0005211244 60 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot -pS6_tot model1_data3 0.007106942 120 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot -pS6_tot model1_data3 0.0945320284 300 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot -pS6_tot model1_data3 0.366852041 600 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot -pS6_tot model1_data3 0.6350909024 900 scaling_pS6_tot 0.025 lin model1_data3_pS6_tot -pS6_tot model1_data3 0.9989387811 1800 scaling_pS6_tot 0.07 lin model1_data3_pS6_tot -pS6_tot model1_data3 0.7818807584 3600 scaling_pS6_tot 0.075 lin model1_data3_pS6_tot -pEGFR_tot model1_data4 0 0 scaling_pEGFR_tot 0.01 lin model1_data4_pEGFR_tot -pEGFR_tot model1_data4 0.287552912 60 scaling_pEGFR_tot 0.15 lin model1_data4_pEGFR_tot -pEGFR_tot model1_data4 0.3027758925 120 scaling_pEGFR_tot 0.12 lin model1_data4_pEGFR_tot -pEGFR_tot model1_data4 0.0587401979 300 scaling_pEGFR_tot 0.15 lin model1_data4_pEGFR_tot -pEGFR_tot model1_data4 0.002420217 600 scaling_pEGFR_tot 0.065 lin model1_data4_pEGFR_tot -pEGFR_tot model1_data4 0.0003476384 900 scaling_pEGFR_tot 0.03 lin model1_data4_pEGFR_tot -pEGFR_tot model1_data4 0.0002698926 1800 scaling_pEGFR_tot 0.02 lin model1_data4_pEGFR_tot -pEGFR_tot model1_data4 0.0002698889 3600 scaling_pEGFR_tot 0.01 lin model1_data4_pEGFR_tot -pAkt_tot model1_data4 0 0 scaling_pAkt_tot 0.01 lin model1_data4_pAkt_tot -pAkt_tot model1_data4 0.5758083456 60 scaling_pAkt_tot 0.05 lin model1_data4_pAkt_tot -pAkt_tot model1_data4 0.8186882204 120 scaling_pAkt_tot 0.05 lin model1_data4_pAkt_tot -pAkt_tot model1_data4 0.573010296 300 scaling_pAkt_tot 0.02 lin model1_data4_pAkt_tot -pAkt_tot model1_data4 0.1916147877 600 scaling_pAkt_tot 0.03 lin model1_data4_pAkt_tot -pAkt_tot model1_data4 0.1261732528 900 scaling_pAkt_tot 0.02 lin model1_data4_pAkt_tot -pAkt_tot model1_data4 0.0883994539 1800 scaling_pAkt_tot 0.02 lin model1_data4_pAkt_tot -pAkt_tot model1_data4 0.0471965113 3600 scaling_pAkt_tot 0.02 lin model1_data4_pAkt_tot -pS6_tot model1_data4 0 0 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot -pS6_tot model1_data4 0.001284326 60 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot -pS6_tot model1_data4 0.0137701475 120 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot -pS6_tot model1_data4 0.1357831768 300 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot -pS6_tot model1_data4 0.4317319675 600 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot -pS6_tot model1_data4 0.6581119566 900 scaling_pS6_tot 0.035 lin model1_data4_pS6_tot -pS6_tot model1_data4 0.8936164338 1800 scaling_pS6_tot 0.08 lin model1_data4_pS6_tot -pS6_tot model1_data4 0.6665565723 3600 scaling_pS6_tot 0.08 lin model1_data4_pS6_tot -pEGFR_tot model1_data5 0 0 scaling_pEGFR_tot 0.01 lin model1_data5_pEGFR_tot -pEGFR_tot model1_data5 0.5650691808 60 scaling_pEGFR_tot 0.3 lin model1_data5_pEGFR_tot -pEGFR_tot model1_data5 0.342130677 120 scaling_pEGFR_tot 0.15 lin model1_data5_pEGFR_tot -pEGFR_tot model1_data5 0.0103850661 300 scaling_pEGFR_tot 0.15 lin model1_data5_pEGFR_tot -pEGFR_tot model1_data5 0.0003059582 600 scaling_pEGFR_tot 0.05 lin model1_data5_pEGFR_tot -pEGFR_tot model1_data5 0.0002956752 900 scaling_pEGFR_tot 0.02 lin model1_data5_pEGFR_tot -pEGFR_tot model1_data5 0.0002956661 1800 scaling_pEGFR_tot 0.02 lin model1_data5_pEGFR_tot -pEGFR_tot model1_data5 0.0002956661 3600 scaling_pEGFR_tot 0.01 lin model1_data5_pEGFR_tot -pAkt_tot model1_data5 0 0 scaling_pAkt_tot 0.01 lin model1_data5_pAkt_tot -pAkt_tot model1_data5 0.8436917241 60 scaling_pAkt_tot 0.1 lin model1_data5_pAkt_tot -pAkt_tot model1_data5 0.8842362231 120 scaling_pAkt_tot 0.025 lin model1_data5_pAkt_tot -pAkt_tot model1_data5 0.385937608 300 scaling_pAkt_tot 0.02 lin model1_data5_pAkt_tot -pAkt_tot model1_data5 0.1201352557 600 scaling_pAkt_tot 0.02 lin model1_data5_pAkt_tot -pAkt_tot model1_data5 0.1006147115 900 scaling_pAkt_tot 0.02 lin model1_data5_pAkt_tot -pAkt_tot model1_data5 0.072815494 1800 scaling_pAkt_tot 0.02 lin model1_data5_pAkt_tot -pAkt_tot model1_data5 0.0398738227 3600 scaling_pAkt_tot 0.01 lin model1_data5_pAkt_tot -pS6_tot model1_data5 0 0 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot -pS6_tot model1_data5 0.0026774961 60 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot -pS6_tot model1_data5 0.0210783997 120 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot -pS6_tot model1_data5 0.1570157565 300 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot -pS6_tot model1_data5 0.4117751573 600 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot -pS6_tot model1_data5 0.5823970015 900 scaling_pS6_tot 0.02 lin model1_data5_pS6_tot -pS6_tot model1_data5 0.7468131737 1800 scaling_pS6_tot 0.04 lin model1_data5_pS6_tot -pS6_tot model1_data5 0.5504628923 3600 scaling_pS6_tot 0.08 lin model1_data5_pS6_tot -pEGFR_tot model1_data6 0 0 scaling_pEGFR_tot 0.01 lin model1_data6_pEGFR_tot -pEGFR_tot model1_data6 0.6597249554 60 scaling_pEGFR_tot 0.1 lin model1_data6_pEGFR_tot -pEGFR_tot model1_data6 0.2653113927 120 scaling_pEGFR_tot 0.1 lin model1_data6_pEGFR_tot -pEGFR_tot model1_data6 0.0045492092 300 scaling_pEGFR_tot 0.2 lin model1_data6_pEGFR_tot -pEGFR_tot model1_data6 0.0003058683 600 scaling_pEGFR_tot 0.05 lin model1_data6_pEGFR_tot -pEGFR_tot model1_data6 0.0003039615 900 scaling_pEGFR_tot 0.02 lin model1_data6_pEGFR_tot -pEGFR_tot model1_data6 0.0003039608 1800 scaling_pEGFR_tot 0.01 lin model1_data6_pEGFR_tot -pEGFR_tot model1_data6 0.0003039608 3600 scaling_pEGFR_tot 0.01 lin model1_data6_pEGFR_tot -pAkt_tot model1_data6 0 0 scaling_pAkt_tot 0.01 lin model1_data6_pAkt_tot -pAkt_tot model1_data6 0.9235457558 60 scaling_pAkt_tot 0.05 lin model1_data6_pAkt_tot -pAkt_tot model1_data6 0.8638192492 120 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot -pAkt_tot model1_data6 0.3145472814 300 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot -pAkt_tot model1_data6 0.1105777921 600 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot -pAkt_tot model1_data6 0.0946003394 900 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot -pAkt_tot model1_data6 0.0687085418 1800 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot -pAkt_tot model1_data6 0.037964715 3600 scaling_pAkt_tot 0.01 lin model1_data6_pAkt_tot -pS6_tot model1_data6 0 0 scaling_pS6_tot 0.01 lin model1_data6_pS6_tot -pS6_tot model1_data6 0.0039799398 60 scaling_pS6_tot 0.01 lin model1_data6_pS6_tot -pS6_tot model1_data6 0.0254606658 120 scaling_pS6_tot 0.01 lin model1_data6_pS6_tot -pS6_tot model1_data6 0.1631478226 300 scaling_pS6_tot 0.01 lin model1_data6_pS6_tot -pS6_tot model1_data6 0.4009703836 600 scaling_pS6_tot 0.02 lin model1_data6_pS6_tot -pS6_tot model1_data6 0.5574326493 900 scaling_pS6_tot 0.03 lin model1_data6_pS6_tot -pS6_tot model1_data6 0.7058108511 1800 scaling_pS6_tot 0.035 lin model1_data6_pS6_tot -pS6_tot model1_data6 0.5194180219 3600 scaling_pS6_tot 0.07 lin model1_data6_pS6_tot +pEGFR_tot condition_step_00_1 0.0 0 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot +pEGFR_tot condition_step_00_1 0.012480366411715928 60 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot +pEGFR_tot condition_step_00_1 0.018707506977356403 120 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot +pEGFR_tot condition_step_00_1 0.015700849112639876 300 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot +pEGFR_tot condition_step_00_1 0.009127527788965412 600 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot +pEGFR_tot condition_step_00_1 0.005303097697048003 900 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot +pEGFR_tot condition_step_00_1 0.0010598594303809863 1800 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot +pEGFR_tot condition_step_00_1 7.418075976475617e-05 3600 scaling_pEGFR_tot 0.01 lin model1_data1_pEGFR_tot +pAkt_tot condition_step_00_1 0.0 0 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot +pAkt_tot condition_step_00_1 0.03571967362373573 60 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot +pAkt_tot condition_step_00_1 0.10589829483225664 120 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot +pAkt_tot condition_step_00_1 0.16811422033992746 300 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot +pAkt_tot condition_step_00_1 0.13609452528616278 600 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot +pAkt_tot condition_step_00_1 0.10689767414384724 900 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot +pAkt_tot condition_step_00_1 0.060261864880839976 1800 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot +pAkt_tot condition_step_00_1 0.02767496261959281 3600 scaling_pAkt_tot 0.01 lin model1_data1_pAkt_tot +pS6_tot condition_step_00_1 0.0 0 scaling_pS6_tot 0.01 lin model1_data1_pS6_tot +pS6_tot condition_step_00_1 5.829970865626934e-05 60 scaling_pS6_tot 0.01 lin model1_data1_pS6_tot +pS6_tot condition_step_00_1 0.000959335241884471 120 scaling_pS6_tot 0.01 lin model1_data1_pS6_tot +pS6_tot condition_step_00_1 0.018661438388824954 300 scaling_pS6_tot 0.01 lin model1_data1_pS6_tot +pS6_tot condition_step_00_1 0.09323749963797492 600 scaling_pS6_tot 0.02 lin model1_data1_pS6_tot +pS6_tot condition_step_00_1 0.18675201104234102 900 scaling_pS6_tot 0.02 lin model1_data1_pS6_tot +pS6_tot condition_step_00_1 0.38460454334751737 1800 scaling_pS6_tot 0.035 lin model1_data1_pS6_tot +pS6_tot condition_step_00_1 0.3669885968601952 3600 scaling_pS6_tot 0.035 lin model1_data1_pS6_tot +pEGFR_tot condition_step_00_3 0.0 0 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot +pEGFR_tot condition_step_00_3 0.03674519730805315 60 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot +pEGFR_tot condition_step_00_3 0.05360268676492265 120 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot +pEGFR_tot condition_step_00_3 0.040225367479225164 300 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot +pEGFR_tot condition_step_00_3 0.019099778836771934 600 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot +pEGFR_tot condition_step_00_3 0.009071367652217055 900 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot +pEGFR_tot condition_step_00_3 0.0010279633390261969 1800 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot +pEGFR_tot condition_step_00_3 8.79345905668471e-05 3600 scaling_pEGFR_tot 0.01 lin model1_data2_pEGFR_tot +pAkt_tot condition_step_00_3 0.0 0 scaling_pAkt_tot 0.01 lin model1_data2_pAkt_tot +pAkt_tot condition_step_00_3 0.10163779699937657 60 scaling_pAkt_tot 0.01 lin model1_data2_pAkt_tot +pAkt_tot condition_step_00_3 0.2724201993678682 120 scaling_pAkt_tot 0.03 lin model1_data2_pAkt_tot +pAkt_tot condition_step_00_3 0.36197640213320137 300 scaling_pAkt_tot 0.01 lin model1_data2_pAkt_tot +pAkt_tot condition_step_00_3 0.2663359423878288 600 scaling_pAkt_tot 0.02 lin model1_data2_pAkt_tot +pAkt_tot condition_step_00_3 0.1946397610070221 900 scaling_pAkt_tot 0.02 lin model1_data2_pAkt_tot +pAkt_tot condition_step_00_3 0.10058579103709434 1800 scaling_pAkt_tot 0.02 lin model1_data2_pAkt_tot +pAkt_tot condition_step_00_3 0.04764267428617345 3600 scaling_pAkt_tot 0.01 lin model1_data2_pAkt_tot +pS6_tot condition_step_00_3 0.0 0 scaling_pS6_tot 0.01 lin model1_data2_pS6_tot +pS6_tot condition_step_00_3 0.0001706435330767396 60 scaling_pS6_tot 0.01 lin model1_data2_pS6_tot +pS6_tot condition_step_00_3 0.0026727931701907223 120 scaling_pS6_tot 0.01 lin model1_data2_pS6_tot +pS6_tot condition_step_00_3 0.0460782248215312 300 scaling_pS6_tot 0.01 lin model1_data2_pS6_tot +pS6_tot condition_step_00_3 0.21054033554381676 600 scaling_pS6_tot 0.02 lin model1_data2_pS6_tot +pS6_tot condition_step_00_3 0.40210221323583173 900 scaling_pS6_tot 0.03 lin model1_data2_pS6_tot +pS6_tot condition_step_00_3 0.7563839705341021 1800 scaling_pS6_tot 0.1 lin model1_data2_pS6_tot +pS6_tot condition_step_00_3 0.6621824263573951 3600 scaling_pS6_tot 0.025 lin model1_data2_pS6_tot +pEGFR_tot condition_step_01_0 0.0 0 scaling_pEGFR_tot 0.01 lin model1_data3_pEGFR_tot +pEGFR_tot condition_step_01_0 0.1148111626001067 60 scaling_pEGFR_tot 0.05 lin model1_data3_pEGFR_tot +pEGFR_tot condition_step_01_0 0.15271982137513834 120 scaling_pEGFR_tot 0.025 lin model1_data3_pEGFR_tot +pEGFR_tot condition_step_01_0 0.07817219585967418 300 scaling_pEGFR_tot 0.065 lin model1_data3_pEGFR_tot +pEGFR_tot condition_step_01_0 0.018452865572308172 600 scaling_pEGFR_tot 0.025 lin model1_data3_pEGFR_tot +pEGFR_tot condition_step_01_0 0.004416559341996262 900 scaling_pEGFR_tot 0.02 lin model1_data3_pEGFR_tot +pEGFR_tot condition_step_01_0 0.00018665301129610926 1800 scaling_pEGFR_tot 0.01 lin model1_data3_pEGFR_tot +pEGFR_tot condition_step_01_0 0.00013185523984646038 3600 scaling_pEGFR_tot 0.01 lin model1_data3_pEGFR_tot +pAkt_tot condition_step_01_0 0.0 0 scaling_pAkt_tot 0.01 lin model1_data3_pAkt_tot +pAkt_tot condition_step_01_0 0.28556263029157786 60 scaling_pAkt_tot 0.1 lin model1_data3_pAkt_tot +pAkt_tot condition_step_01_0 0.5871858562106247 120 scaling_pAkt_tot 0.07 lin model1_data3_pAkt_tot +pAkt_tot condition_step_01_0 0.5697990776354793 300 scaling_pAkt_tot 0.03 lin model1_data3_pAkt_tot +pAkt_tot condition_step_01_0 0.3255369327733615 600 scaling_pAkt_tot 0.03 lin model1_data3_pAkt_tot +pAkt_tot condition_step_01_0 0.19622609563116897 900 scaling_pAkt_tot 0.03 lin model1_data3_pAkt_tot +pAkt_tot condition_step_01_0 0.10636030480500712 1800 scaling_pAkt_tot 0.02 lin model1_data3_pAkt_tot +pAkt_tot condition_step_01_0 0.05474517710127448 3600 scaling_pAkt_tot 0.01 lin model1_data3_pAkt_tot +pS6_tot condition_step_01_0 0.0 0 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot +pS6_tot condition_step_01_0 0.000524475262481269 60 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot +pS6_tot condition_step_01_0 0.007143844432165558 120 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot +pS6_tot condition_step_01_0 0.09491069144153012 300 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot +pS6_tot condition_step_01_0 0.36794452835273667 600 scaling_pS6_tot 0.01 lin model1_data3_pS6_tot +pS6_tot condition_step_01_0 0.6363468304512627 900 scaling_pS6_tot 0.025 lin model1_data3_pS6_tot +pS6_tot condition_step_01_0 0.9999176306937233 1800 scaling_pS6_tot 0.07 lin model1_data3_pS6_tot +pS6_tot condition_step_01_0 0.7837469282313485 3600 scaling_pS6_tot 0.075 lin model1_data3_pS6_tot +pEGFR_tot condition_step_03_0 0.0 0 scaling_pEGFR_tot 0.01 lin model1_data4_pEGFR_tot +pEGFR_tot condition_step_03_0 0.2886782406856652 60 scaling_pEGFR_tot 0.15 lin model1_data4_pEGFR_tot +pEGFR_tot condition_step_03_0 0.30242804281267716 120 scaling_pEGFR_tot 0.12 lin model1_data4_pEGFR_tot +pEGFR_tot condition_step_03_0 0.05715699506779033 300 scaling_pEGFR_tot 0.15 lin model1_data4_pEGFR_tot +pEGFR_tot condition_step_03_0 0.0021515820456298215 600 scaling_pEGFR_tot 0.065 lin model1_data4_pEGFR_tot +pEGFR_tot condition_step_03_0 0.0002331126286492285 900 scaling_pEGFR_tot 0.03 lin model1_data4_pEGFR_tot +pEGFR_tot condition_step_03_0 0.00016512523251489418 1800 scaling_pEGFR_tot 0.02 lin model1_data4_pEGFR_tot +pEGFR_tot condition_step_03_0 0.00016512250714135668 3600 scaling_pEGFR_tot 0.01 lin model1_data4_pEGFR_tot +pAkt_tot condition_step_03_0 0.0 0 scaling_pAkt_tot 0.01 lin model1_data4_pAkt_tot +pAkt_tot condition_step_03_0 0.5775196213931701 60 scaling_pAkt_tot 0.05 lin model1_data4_pAkt_tot +pAkt_tot condition_step_03_0 0.8200665352991877 120 scaling_pAkt_tot 0.05 lin model1_data4_pAkt_tot +pAkt_tot condition_step_03_0 0.5723434671145193 300 scaling_pAkt_tot 0.02 lin model1_data4_pAkt_tot +pAkt_tot condition_step_03_0 0.19045378872267194 600 scaling_pAkt_tot 0.03 lin model1_data4_pAkt_tot +pAkt_tot condition_step_03_0 0.1261136825380296 900 scaling_pAkt_tot 0.02 lin model1_data4_pAkt_tot +pAkt_tot condition_step_03_0 0.08839189817721442 1800 scaling_pAkt_tot 0.02 lin model1_data4_pAkt_tot +pAkt_tot condition_step_03_0 0.04655742558075636 3600 scaling_pAkt_tot 0.02 lin model1_data4_pAkt_tot +pS6_tot condition_step_03_0 0.0 0 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot +pS6_tot condition_step_03_0 0.0012913696656530827 60 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot +pS6_tot condition_step_03_0 0.013823815051844856 120 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot +pS6_tot condition_step_03_0 0.13614814190917518 300 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot +pS6_tot condition_step_03_0 0.43222600720052035 600 scaling_pS6_tot 0.01 lin model1_data4_pS6_tot +pS6_tot condition_step_03_0 0.6582843946021298 900 scaling_pS6_tot 0.035 lin model1_data4_pS6_tot +pS6_tot condition_step_03_0 0.8936402752356469 1800 scaling_pS6_tot 0.08 lin model1_data4_pS6_tot +pS6_tot condition_step_03_0 0.6658815407462093 3600 scaling_pS6_tot 0.08 lin model1_data4_pS6_tot +pEGFR_tot condition_step_10_0 0.0 0 scaling_pEGFR_tot 0.01 lin model1_data5_pEGFR_tot +pEGFR_tot condition_step_10_0 0.5676704383138094 60 scaling_pEGFR_tot 0.3 lin model1_data5_pEGFR_tot +pEGFR_tot condition_step_10_0 0.33967350986051936 120 scaling_pEGFR_tot 0.15 lin model1_data5_pEGFR_tot +pEGFR_tot condition_step_10_0 0.009400619471596115 300 scaling_pEGFR_tot 0.15 lin model1_data5_pEGFR_tot +pEGFR_tot condition_step_10_0 0.00018845153139739382 600 scaling_pEGFR_tot 0.05 lin model1_data5_pEGFR_tot +pEGFR_tot condition_step_10_0 0.00018112668995170903 900 scaling_pEGFR_tot 0.02 lin model1_data5_pEGFR_tot +pEGFR_tot condition_step_10_0 0.00018112197383655625 1800 scaling_pEGFR_tot 0.02 lin model1_data5_pEGFR_tot +pEGFR_tot condition_step_10_0 0.00018112197383884256 3600 scaling_pEGFR_tot 0.01 lin model1_data5_pEGFR_tot +pAkt_tot condition_step_10_0 0.0 0 scaling_pAkt_tot 0.01 lin model1_data5_pAkt_tot +pAkt_tot condition_step_10_0 0.844867156245151 60 scaling_pAkt_tot 0.1 lin model1_data5_pAkt_tot +pAkt_tot condition_step_10_0 0.8849068422667229 120 scaling_pAkt_tot 0.025 lin model1_data5_pAkt_tot +pAkt_tot condition_step_10_0 0.3827420055965652 300 scaling_pAkt_tot 0.02 lin model1_data5_pAkt_tot +pAkt_tot condition_step_10_0 0.11977132624725684 600 scaling_pAkt_tot 0.02 lin model1_data5_pAkt_tot +pAkt_tot condition_step_10_0 0.10030494068131744 900 scaling_pAkt_tot 0.02 lin model1_data5_pAkt_tot +pAkt_tot condition_step_10_0 0.07230920319529495 1800 scaling_pAkt_tot 0.02 lin model1_data5_pAkt_tot +pAkt_tot condition_step_10_0 0.03872221513723069 3600 scaling_pAkt_tot 0.01 lin model1_data5_pAkt_tot +pS6_tot condition_step_10_0 0.0 0 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot +pS6_tot condition_step_10_0 0.002688760168924027 60 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot +pS6_tot condition_step_10_0 0.021137630242921993 120 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot +pS6_tot condition_step_10_0 0.15721132436693347 300 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot +pS6_tot condition_step_10_0 0.41147869920730656 600 scaling_pS6_tot 0.01 lin model1_data5_pS6_tot +pS6_tot condition_step_10_0 0.5816658865220378 900 scaling_pS6_tot 0.02 lin model1_data5_pS6_tot +pS6_tot condition_step_10_0 0.7454041663064397 1800 scaling_pS6_tot 0.04 lin model1_data5_pS6_tot +pS6_tot condition_step_10_0 0.5470002311288191 3600 scaling_pS6_tot 0.08 lin model1_data5_pS6_tot +pEGFR_tot condition_step_30_0 0.0 0 scaling_pEGFR_tot 0.01 lin model1_data6_pEGFR_tot +pEGFR_tot condition_step_30_0 0.6616674233641531 60 scaling_pEGFR_tot 0.1 lin model1_data6_pEGFR_tot +pEGFR_tot condition_step_30_0 0.2608340355735843 120 scaling_pEGFR_tot 0.1 lin model1_data6_pEGFR_tot +pEGFR_tot condition_step_30_0 0.004016150335610498 300 scaling_pEGFR_tot 0.2 lin model1_data6_pEGFR_tot +pEGFR_tot condition_step_30_0 0.0001876717298537902 600 scaling_pEGFR_tot 0.05 lin model1_data6_pEGFR_tot +pEGFR_tot condition_step_30_0 0.00018627933745822008 900 scaling_pEGFR_tot 0.02 lin model1_data6_pEGFR_tot +pEGFR_tot condition_step_30_0 0.0001862789481140307 1800 scaling_pEGFR_tot 0.01 lin model1_data6_pEGFR_tot +pEGFR_tot condition_step_30_0 0.0001862789481162307 3600 scaling_pEGFR_tot 0.01 lin model1_data6_pEGFR_tot +pAkt_tot condition_step_30_0 0.0 0 scaling_pAkt_tot 0.01 lin model1_data6_pAkt_tot +pAkt_tot condition_step_30_0 0.9243819721360509 60 scaling_pAkt_tot 0.05 lin model1_data6_pAkt_tot +pAkt_tot condition_step_30_0 0.8637204571184451 120 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot +pAkt_tot condition_step_30_0 0.31206244424114904 300 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot +pAkt_tot condition_step_30_0 0.11027573547753863 600 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot +pAkt_tot condition_step_30_0 0.0942146449555446 900 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot +pAkt_tot condition_step_30_0 0.06808725487689075 1800 scaling_pAkt_tot 0.02 lin model1_data6_pAkt_tot +pAkt_tot condition_step_30_0 0.03667874310909305 3600 scaling_pAkt_tot 0.01 lin model1_data6_pAkt_tot +pS6_tot condition_step_30_0 0.0 0 scaling_pS6_tot 0.01 lin model1_data6_pS6_tot +pS6_tot condition_step_30_0 0.00399438146767243 60 scaling_pS6_tot 0.01 lin model1_data6_pS6_tot +pS6_tot condition_step_30_0 0.025521860562909136 120 scaling_pS6_tot 0.01 lin model1_data6_pS6_tot +pS6_tot condition_step_30_0 0.16323537546041705 300 scaling_pS6_tot 0.01 lin model1_data6_pS6_tot +pS6_tot condition_step_30_0 0.40058494805328826 600 scaling_pS6_tot 0.02 lin model1_data6_pS6_tot +pS6_tot condition_step_30_0 0.5566922316075167 900 scaling_pS6_tot 0.03 lin model1_data6_pS6_tot +pS6_tot condition_step_30_0 0.7042997888996284 1800 scaling_pS6_tot 0.035 lin model1_data6_pS6_tot +pS6_tot condition_step_30_0 0.5153837860708252 3600 scaling_pS6_tot 0.07 lin model1_data6_pS6_tot diff --git a/problems/Okuonghae_ChaosSolitonsFractals2020/v1/simulations.tsv b/problems/Okuonghae_ChaosSolitonsFractals2020/v1/simulations.tsv new file mode 100644 index 0000000..098442e --- /dev/null +++ b/problems/Okuonghae_ChaosSolitonsFractals2020/v1/simulations.tsv @@ -0,0 +1,93 @@ +observableId simulationConditionId simulation time noiseParameters datasetId +observable_ActiveCases cond1 1.0 0 sd_ActiveCases id1 +observable_ActiveCases cond1 3.720654398600152 1 sd_ActiveCases id1 +observable_ActiveCases cond1 6.351796012907393 2 sd_ActiveCases id1 +observable_ActiveCases cond1 8.931214467167091 3 sd_ActiveCases id1 +observable_ActiveCases cond1 14.05397860120295 5 sd_ActiveCases id1 +observable_ActiveCases cond1 16.646803748109086 6 sd_ActiveCases id1 +observable_ActiveCases cond1 19.289428072908006 7 sd_ActiveCases id1 +observable_ActiveCases cond1 22.00162982042648 8 sd_ActiveCases id1 +observable_ActiveCases cond1 24.802388181582653 9 sd_ActiveCases id1 +observable_ActiveCases cond1 27.710279720971243 10 sd_ActiveCases id1 +observable_ActiveCases cond1 33.921528320109374 12 sd_ActiveCases id1 +observable_ActiveCases cond1 37.2624934553939 13 sd_ActiveCases id1 +observable_ActiveCases cond1 40.786191713090574 14 sd_ActiveCases id1 +observable_ActiveCases cond1 44.51282922508271 15 sd_ActiveCases id1 +observable_ActiveCases cond1 48.463457576843695 16 sd_ActiveCases id1 +observable_ActiveCases cond1 52.66011993382021 17 sd_ActiveCases id1 +observable_ActiveCases cond1 57.12599502304378 18 sd_ActiveCases id1 +observable_ActiveCases cond1 61.88554155567069 19 sd_ActiveCases id1 +observable_ActiveCases cond1 66.96464513008713 20 sd_ActiveCases id1 +observable_ActiveCases cond1 72.39076929282596 21 sd_ActiveCases id1 +observable_ActiveCases cond1 78.19311219629927 22 sd_ActiveCases id1 +observable_ActiveCases cond1 84.40277015186973 23 sd_ActiveCases id1 +observable_ActiveCases cond1 91.05290926787755 24 sd_ActiveCases id1 +observable_ActiveCases cond1 98.17894633336948 25 sd_ActiveCases id1 +observable_ActiveCases cond1 105.81874007282131 26 sd_ActiveCases id1 +observable_ActiveCases cond1 114.01279390211185 27 sd_ActiveCases id1 +observable_ActiveCases cond1 122.80447133793251 28 sd_ActiveCases id1 +observable_ActiveCases cond1 132.24022523408956 29 sd_ActiveCases id1 +observable_ActiveCases cond1 142.3698420682592 30 sd_ActiveCases id1 +observable_ActiveCases cond1 153.24670254988564 31 sd_ActiveCases id1 +observable_ActiveCases cond1 164.92805986214995 32 sd_ActiveCases id1 +observable_ActiveCases cond1 177.47533694519123 33 sd_ActiveCases id1 +observable_ActiveCases cond1 190.95444426851654 34 sd_ActiveCases id1 +observable_ActiveCases cond1 205.43611963398706 35 sd_ActiveCases id1 +observable_ActiveCases cond1 220.99629162216976 36 sd_ActiveCases id1 +observable_ActiveCases cond1 237.71646839656947 37 sd_ActiveCases id1 +observable_ActiveCases cond1 255.68415365286398 38 sd_ActiveCases id1 +observable_ActiveCases cond1 274.9932916039375 39 sd_ActiveCases id1 +observable_ActiveCases cond1 295.744743008356 40 sd_ActiveCases id1 +observable_ActiveCases cond1 318.0467943122455 41 sd_ActiveCases id1 +observable_ActiveCases cond1 342.01570213008586 42 sd_ActiveCases id1 +observable_ActiveCases cond1 367.77627534835165 43 sd_ActiveCases id1 +observable_ActiveCases cond1 395.46249729107484 44 sd_ActiveCases id1 +observable_ActiveCases cond1 425.21819044439906 45 sd_ActiveCases id1 +observable_ActiveCases cond1 457.1977263975037 46 sd_ActiveCases id1 +observable_ActiveCases cond1 491.5667837001762 47 sd_ActiveCases id1 +observable_Cumulative cond1 1.0 0 sd_Cumulative id1 +observable_Cumulative cond1 3.914171553297707 1 sd_Cumulative id1 +observable_Cumulative cond1 6.957075227766987 2 sd_Cumulative id1 +observable_Cumulative cond1 10.1607897695009 3 sd_Cumulative id1 +observable_Cumulative cond1 17.160380963911155 5 sd_Cumulative id1 +observable_Cumulative cond1 21.006552305093308 6 sd_Cumulative id1 +observable_Cumulative cond1 25.116165323489025 7 sd_Cumulative id1 +observable_Cumulative cond1 29.513879854127293 8 sd_Cumulative id1 +observable_Cumulative cond1 34.22513617993468 9 sd_Cumulative id1 +observable_Cumulative cond1 39.2765031414173 10 sd_Cumulative id1 +observable_Cumulative cond1 50.5131628693798 12 sd_Cumulative id1 +observable_Cumulative cond1 56.759632576210684 13 sd_Cumulative id1 +observable_Cumulative cond1 63.46900754659008 14 sd_Cumulative id1 +observable_Cumulative cond1 70.6772369543411 15 sd_Cumulative id1 +observable_Cumulative cond1 78.42279910919424 16 sd_Cumulative id1 +observable_Cumulative cond1 86.74692261932448 17 sd_Cumulative id1 +observable_Cumulative cond1 95.69381723730635 18 sd_Cumulative id1 +observable_Cumulative cond1 105.31091690503321 19 sd_Cumulative id1 +observable_Cumulative cond1 115.64913716665708 20 sd_Cumulative id1 +observable_Cumulative cond1 126.76314889259648 21 sd_Cumulative id1 +observable_Cumulative cond1 138.71167015624744 22 sd_Cumulative id1 +observable_Cumulative cond1 151.5577780764682 23 sd_Cumulative id1 +observable_Cumulative cond1 165.3692424184475 24 sd_Cumulative id1 +observable_Cumulative cond1 180.21888283179572 25 sd_Cumulative id1 +observable_Cumulative cond1 196.1849516465987 26 sd_Cumulative id1 +observable_Cumulative cond1 213.35154424971074 27 sd_Cumulative id1 +observable_Cumulative cond1 231.80903918479498 28 sd_Cumulative id1 +observable_Cumulative cond1 251.65457022370035 29 sd_Cumulative id1 +observable_Cumulative cond1 272.99253281758416 30 sd_Cumulative id1 +observable_Cumulative cond1 295.9351274813509 31 sd_Cumulative id1 +observable_Cumulative cond1 320.60294279465154 32 sd_Cumulative id1 +observable_Cumulative cond1 347.12558094585387 33 sd_Cumulative id1 +observable_Cumulative cond1 375.64232886498513 34 sd_Cumulative id1 +observable_Cumulative cond1 406.3028782292644 35 sd_Cumulative id1 +observable_Cumulative cond1 439.26809781225217 36 sd_Cumulative id1 +observable_Cumulative cond1 474.7108619030989 37 sd_Cumulative id1 +observable_Cumulative cond1 512.8169387150994 38 sd_Cumulative id1 +observable_Cumulative cond1 553.785942966447 39 sd_Cumulative id1 +observable_Cumulative cond1 597.8323571123105 40 sd_Cumulative id1 +observable_Cumulative cond1 645.1866258874693 41 sd_Cumulative id1 +observable_Cumulative cond1 696.0963292100806 42 sd_Cumulative id1 +observable_Cumulative cond1 750.827438680458 43 sd_Cumulative id1 +observable_Cumulative cond1 809.6656633141107 44 sd_Cumulative id1 +observable_Cumulative cond1 872.9178903471569 45 sd_Cumulative id1 +observable_Cumulative cond1 940.9137273902172 46 sd_Cumulative id1 +observable_Cumulative cond1 1014.0071523955352 47 sd_Cumulative id1 diff --git a/problems/Oliveira_NatCommun2021/v1/simulations.tsv b/problems/Oliveira_NatCommun2021/v1/simulations.tsv new file mode 100644 index 0000000..fdddb9f --- /dev/null +++ b/problems/Oliveira_NatCommun2021/v1/simulations.tsv @@ -0,0 +1,121 @@ +observableId simulationConditionId simulation time noiseParameters datasetId +cumulative_cases interior 4.016823843999999 0 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.0 0 sd_cumulative_deaths dataset_ +cumulative_cases interior 4.232910613332748 1 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.0018464674802871025 1 sd_cumulative_deaths dataset_ +cumulative_cases interior 4.720373390831938 2 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.006844705972374982 2 sd_cumulative_deaths dataset_ +cumulative_cases interior 5.407971148239844 3 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.014484301565801425 3 sd_cumulative_deaths dataset_ +cumulative_cases interior 6.268988875481741 4 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.024530264139292924 4 sd_cumulative_deaths dataset_ +cumulative_cases interior 7.301012212500675 5 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.03692767942870849 5 sd_cumulative_deaths dataset_ +cumulative_cases interior 8.51586127128967 6 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.05175107826893596 6 sd_cumulative_deaths dataset_ +cumulative_cases interior 9.934744287239655 7 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.06917820778330565 7 sd_cumulative_deaths dataset_ +cumulative_cases interior 11.586119799970927 8 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.08947766440500492 8 sd_cumulative_deaths dataset_ +cumulative_cases interior 13.504994613978068 9 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.11300490241069465 9 sd_cumulative_deaths dataset_ +cumulative_cases interior 15.733017275159906 10 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.14020376750961808 10 sd_cumulative_deaths dataset_ +cumulative_cases interior 18.31905058678254 11 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.17161210026185553 11 sd_cumulative_deaths dataset_ +cumulative_cases interior 21.32007336262766 12 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.20787071149288947 12 sd_cumulative_deaths dataset_ +cumulative_cases interior 24.80234846433119 13 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.2497354609036835 13 sd_cumulative_deaths dataset_ +cumulative_cases interior 28.842840629143765 14 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.2980924304263014 14 sd_cumulative_deaths dataset_ +cumulative_cases interior 33.530893803503716 15 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.35397635850191944 15 sd_cumulative_deaths dataset_ +cumulative_cases interior 38.97019398767455 16 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.4185926342802002 16 sd_cumulative_deaths dataset_ +cumulative_cases interior 45.281055290777665 17 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.4933432654642824 17 sd_cumulative_deaths dataset_ +cumulative_cases interior 52.603076779374405 18 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.5798573435918158 18 sd_cumulative_deaths dataset_ +cumulative_cases interior 61.09822728400052 19 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.6800266442273317 19 sd_cumulative_deaths dataset_ +cumulative_cases interior 70.95442549274934 20 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.7960471227460275 20 sd_cumulative_deaths dataset_ +cumulative_cases interior 82.38969392845338 21 sd_cumulative_cases dataset_ +cumulative_deaths interior 0.9304672031511093 21 sd_cumulative_deaths dataset_ +cumulative_cases interior 95.65697823046153 22 sd_cumulative_cases dataset_ +cumulative_deaths interior 1.086243912175769 22 sd_cumulative_deaths dataset_ +cumulative_cases interior 111.04973789973741 23 sd_cumulative_cases dataset_ +cumulative_deaths interior 1.2668080876780563 23 sd_cumulative_deaths dataset_ +cumulative_cases interior 128.90843164105328 24 sd_cumulative_cases dataset_ +cumulative_deaths interior 1.4761400928496606 24 sd_cumulative_deaths dataset_ +cumulative_cases interior 149.62804011326682 25 sd_cumulative_cases dataset_ +cumulative_deaths interior 1.718857701615158 25 sd_cumulative_deaths dataset_ +cumulative_cases interior 173.66679162401041 26 sd_cumulative_cases dataset_ +cumulative_deaths interior 2.000318090053818 26 sd_cumulative_deaths dataset_ +cumulative_cases interior 201.55628262682112 27 sd_cumulative_cases dataset_ +cumulative_deaths interior 2.326736180411507 27 sd_cumulative_deaths dataset_ +cumulative_cases interior 233.91321535794964 28 sd_cumulative_cases dataset_ +cumulative_deaths interior 2.7053219451636936 28 sd_cumulative_deaths dataset_ +cumulative_cases interior 271.45301013076346 29 sd_cumulative_cases dataset_ +cumulative_deaths interior 3.1444396953851945 29 sd_cumulative_deaths dataset_ +cumulative_cases interior 311.7610503112301 30 sd_cumulative_cases dataset_ +cumulative_deaths interior 3.6535348128084797 30 sd_cumulative_deaths dataset_ +cumulative_cases interior 352.60732884364944 31 sd_cumulative_cases dataset_ +cumulative_deaths interior 4.240785823963287 31 sd_cumulative_deaths dataset_ +cumulative_cases interior 394.74255570668157 32 sd_cumulative_cases dataset_ +cumulative_deaths interior 4.911677758895421 32 sd_cumulative_deaths dataset_ +cumulative_cases interior 438.6417319626975 33 sd_cumulative_cases dataset_ +cumulative_deaths interior 5.670089032939824 33 sd_cumulative_deaths dataset_ +cumulative_cases interior 484.6280292281781 34 sd_cumulative_cases dataset_ +cumulative_deaths interior 6.519086691025875 34 sd_cumulative_deaths dataset_ +cumulative_cases interior 532.9424427202579 35 sd_cumulative_cases dataset_ +cumulative_deaths interior 7.4613840462458505 35 sd_cumulative_deaths dataset_ +cumulative_cases interior 583.783035449421 36 sd_cumulative_cases dataset_ +cumulative_deaths interior 8.499606905122533 36 sd_cumulative_deaths dataset_ +cumulative_cases interior 637.327132902167 37 sd_cumulative_cases dataset_ +cumulative_deaths interior 9.636450950217636 37 sd_cumulative_deaths dataset_ +cumulative_cases interior 693.7439618955445 38 sd_cumulative_cases dataset_ +cumulative_deaths interior 10.874777036800714 38 sd_cumulative_deaths dataset_ +cumulative_cases interior 753.2019374798281 39 sd_cumulative_cases dataset_ +cumulative_deaths interior 12.21767097325012 39 sd_cumulative_deaths dataset_ +cumulative_cases interior 815.8729565828194 40 sd_cumulative_cases dataset_ +cumulative_deaths interior 13.668482955230626 40 sd_cumulative_deaths dataset_ +cumulative_cases interior 881.9350221363763 41 sd_cumulative_cases dataset_ +cumulative_deaths interior 15.230855370373044 41 sd_cumulative_deaths dataset_ +cumulative_cases interior 951.573940945607 42 sd_cumulative_cases dataset_ +cumulative_deaths interior 16.90874402547355 42 sd_cumulative_deaths dataset_ +cumulative_cases interior 1024.9845129497658 43 sd_cumulative_cases dataset_ +cumulative_deaths interior 18.706435757827837 43 sd_cumulative_deaths dataset_ +cumulative_cases interior 1102.371446877746 44 sd_cumulative_cases dataset_ +cumulative_deaths interior 20.628564193359036 44 sd_cumulative_deaths dataset_ +cumulative_cases interior 1183.9501348530016 45 sd_cumulative_cases dataset_ +cumulative_deaths interior 22.680124721622295 45 sd_cumulative_deaths dataset_ +cumulative_cases interior 1269.9473610503549 46 sd_cumulative_cases dataset_ +cumulative_deaths interior 24.866489354294696 46 sd_cumulative_deaths dataset_ +cumulative_cases interior 1360.6019872403692 47 sd_cumulative_cases dataset_ +cumulative_deaths interior 27.1934218950077 47 sd_cumulative_deaths dataset_ +cumulative_cases interior 1456.165640137862 48 sd_cumulative_cases dataset_ +cumulative_deaths interior 29.667093709884874 48 sd_cumulative_deaths dataset_ +cumulative_cases interior 1556.9034150852556 49 sd_cumulative_cases dataset_ +cumulative_deaths interior 32.294100296295454 49 sd_cumulative_deaths dataset_ +cumulative_cases interior 1663.0946052712445 50 sd_cumulative_cases dataset_ +cumulative_deaths interior 35.08147880232098 50 sd_cumulative_deaths dataset_ +cumulative_cases interior 1775.0334622789826 51 sd_cumulative_cases dataset_ +cumulative_deaths interior 38.036726610746506 51 sd_cumulative_deaths dataset_ +cumulative_cases interior 1893.029992183682 52 sd_cumulative_cases dataset_ +cumulative_deaths interior 41.1678210857592 52 sd_cumulative_deaths dataset_ +cumulative_cases interior 2017.4107903660342 53 sd_cumulative_cases dataset_ +cumulative_deaths interior 44.48324056464232 53 sd_cumulative_deaths dataset_ +cumulative_cases interior 2148.51991777127 54 sd_cumulative_cases dataset_ +cumulative_deaths interior 47.99198667154463 54 sd_cumulative_deaths dataset_ +cumulative_cases interior 2286.7198210773486 55 sd_cumulative_cases dataset_ +cumulative_deaths interior 51.703608025525845 55 sd_cumulative_deaths dataset_ +cumulative_cases interior 2432.392299102784 56 sd_cumulative_cases dataset_ +cumulative_deaths interior 55.628225412321804 56 sd_cumulative_deaths dataset_ +cumulative_cases interior 2585.9395177806973 57 sd_cumulative_cases dataset_ +cumulative_deaths interior 59.776558489567 57 sd_cumulative_deaths dataset_ +cumulative_cases interior 2747.785076066559 58 sd_cumulative_cases dataset_ +cumulative_deaths interior 64.15995409662534 58 sd_cumulative_deaths dataset_ +cumulative_cases interior 2918.3751251481613 59 sd_cumulative_cases dataset_ +cumulative_deaths interior 68.7904162402748 59 sd_cumulative_deaths dataset_ diff --git a/problems/Perelson_Science1996/v1/simulations.tsv b/problems/Perelson_Science1996/v1/simulations.tsv index e68cd7a..d517155 100644 --- a/problems/Perelson_Science1996/v1/simulations.tsv +++ b/problems/Perelson_Science1996/v1/simulations.tsv @@ -1,17 +1,17 @@ observableId preequilibrationConditionId simulationConditionId simulation time observableParameters noiseParameters observableTransformation noiseDistribution -task0_model0_perelson1_V condition1 1860000 0 1 log10 normal -task0_model0_perelson1_V condition1 1979067.19116451 0.105 1 log10 normal -task0_model0_perelson1_V condition1 2036200.82349015 0.169 1 log10 normal -task0_model0_perelson1_V condition1 2110605.53393048 0.282 1 log10 normal -task0_model0_perelson1_V condition1 2170386.58687064 0.492 1 log10 normal -task0_model0_perelson1_V condition1 2133014.95269381 0.757 1 log10 normal -task0_model0_perelson1_V condition1 2007892.04532337 1.029 1 log10 normal -task0_model0_perelson1_V condition1 1866529.16992371 1.253 1 log10 normal -task0_model0_perelson1_V condition1 1667316.74545722 1.533 1 log10 normal -task0_model0_perelson1_V condition1 1508578.7515073 1.75 1 log10 normal -task0_model0_perelson1_V condition1 1304224.95565882 2.038 1 log10 normal -task0_model0_perelson1_V condition1 745147.675932322 3.013 1 log10 normal -task0_model0_perelson1_V condition1 404793.605719818 3.987 1 log10 normal -task0_model0_perelson1_V condition1 214718.67877913 4.968 1 log10 normal -task0_model0_perelson1_V condition1 111378.497695453 5.972 1 log10 normal -task0_model0_perelson1_V condition1 57731.3816378903 6.973 1 log10 normal +task0_model0_perelson1_V condition1 1860000.0 0 1 log10 normal +task0_model0_perelson1_V condition1 1859281.260373289 0.105 1 log10 normal +task0_model0_perelson1_V condition1 1857219.5663062893 0.169 1 log10 normal +task0_model0_perelson1_V condition1 1848638.4703770746 0.282 1 log10 normal +task0_model0_perelson1_V condition1 1812120.1993839357 0.492 1 log10 normal +task0_model0_perelson1_V condition1 1728263.03640854 0.757 1 log10 normal +task0_model0_perelson1_V condition1 1608815.6791831392 1.029 1 log10 normal +task0_model0_perelson1_V condition1 1495225.9952656787 1.253 1 log10 normal +task0_model0_perelson1_V condition1 1345380.619535358 1.533 1 log10 normal +task0_model0_perelson1_V condition1 1229342.8058591573 1.75 1 log10 normal +task0_model0_perelson1_V condition1 1081458.8464350805 2.038 1 log10 normal +task0_model0_perelson1_V condition1 671706.4854312212 3.013 1 log10 normal +task0_model0_perelson1_V condition1 405639.170141612 3.987 1 log10 normal +task0_model0_perelson1_V condition1 241982.66835108443 4.968 1 log10 normal +task0_model0_perelson1_V condition1 142258.69595914753 5.972 1 log10 normal +task0_model0_perelson1_V condition1 83708.79730856746 6.973 1 log10 normal diff --git a/problems/Raia_CancerResearch2011/v1/simulations.tsv b/problems/Raia_CancerResearch2011/v1/simulations.tsv index d1c9579..badcb5b 100644 --- a/problems/Raia_CancerResearch2011/v1/simulations.tsv +++ b/problems/Raia_CancerResearch2011/v1/simulations.tsv @@ -1,206 +1,206 @@ -observableId preequilibrationCondition simulationCondition simulation time observableParameters noiseParameters -RecSurf model1_data1 1.3 0 -RecSurf model1_data1 1.427926242 10 -RecSurf model1_data1 1.4319383562 20 -RecSurf model1_data1 1.432064218 30 -RecSurf model1_data1 1.4320683867 60 -RecSurf model1_data1 1.4320684562 90 -RecSurf model1_data1 1.4320684584 120 -IL13_cell model1_data1 0 0 -IL13_cell model1_data1 0 15 -IL13_cell model1_data1 0 30 -IL13_cell model1_data1 0 60 -IL13_cell model1_data1 0 90 -IL13_cell model1_data1 0 120 -SOCS3mRNA model1_data1 0 0 -SOCS3mRNA model1_data1 0 20 -SOCS3mRNA model1_data1 0 30 -SOCS3mRNA model1_data1 0 40 -SOCS3mRNA model1_data1 0 60 -SOCS3mRNA model1_data1 0 80 -SOCS3mRNA model1_data1 0 90 -SOCS3mRNA model1_data1 0 100 -SOCS3mRNA model1_data1 0 120 -CD274mRNA model1_data1 0 30 -CD274mRNA model1_data1 0 60 -CD274mRNA model1_data1 0 90 -CD274mRNA model1_data1 0 120 -SOCS3 model1_data1 0 0 -SOCS3 model1_data1 0 20 -SOCS3 model1_data1 0 40 -SOCS3 model1_data1 0 60 -SOCS3 model1_data1 0 90 -SOCS3 model1_data1 0 120 -IL13_cell model1_data2 3.7024348123 5 -IL13_cell model1_data2 5.1026012059 10 -IL13_cell model1_data2 5.6061765227 15 -IL13_cell model1_data2 5.7871881096 20 -IL13_cell model1_data2 5.8672215586 30 -IL13_cell model1_data2 5.8625775062 40 -IL13_cell model1_data2 5.8456085207 50 -IL13_cell model1_data2 5.8268553725 60 -IL13_cell model1_data2 5.788996529 80 -IL13_cell model1_data2 5.7514395189 100 -IL13_cell model1_data2 5.7142386514 120 -pIL4Ra model1_data2 0 0 -pIL4Ra model1_data2 1.226370545 4 -pIL4Ra model1_data2 1.4137574553 5 -pIL4Ra model1_data2 1.6865488089 7 -pIL4Ra model1_data2 1.9251305934 10 -pIL4Ra model1_data2 2.0946684877 15 -pIL4Ra model1_data2 2.1495822965 20 -pIL4Ra model1_data2 2.1673789234 30 -pIL4Ra model1_data2 2.160402643 40 -pIL4Ra model1_data2 2.1555141743 45 -pIL4Ra model1_data2 2.140140007 60 -pJAK2 model1_data2 0 0 -pJAK2 model1_data2 0.9775092322 4 -pJAK2 model1_data2 1.2102338931 5 -pJAK2 model1_data2 1.5564372517 7 -pJAK2 model1_data2 1.8547029057 10 -pJAK2 model1_data2 2.0411811523 15 -pJAK2 model1_data2 2.0678225772 20 -pJAK2 model1_data2 2.036161077 25 -pJAK2 model1_data2 1.9807970906 30 -pJAK2 model1_data2 1.8462457668 40 -pJAK2 model1_data2 1.7766686151 45 -pJAK2 model1_data2 1.7084751945 50 -pJAK2 model1_data2 1.57993676 60 -pJAK2 model1_data2 1.3627465451 80 -pJAK2 model1_data2 1.1975863655 100 -pJAK2 model1_data2 1.0750810942 120 -SOCS3mRNA model1_data2 0 0 -SOCS3mRNA model1_data2 54.7642430565 20 -SOCS3mRNA model1_data2 122.3095653067 30 -SOCS3mRNA model1_data2 200.2799185297 40 -SOCS3mRNA model1_data2 364.8542894841 60 -SOCS3mRNA model1_data2 527.0847080334 80 -SOCS3mRNA model1_data2 605.5634673119 90 -SOCS3mRNA model1_data2 682.051466418 100 -SOCS3mRNA model1_data2 829.1181009635 120 -CD274mRNA model1_data2 0.253765268 30 -CD274mRNA model1_data2 0.75699187 60 -CD274mRNA model1_data2 1.2564101197 90 -CD274mRNA model1_data2 1.7202364883 120 -SOCS3 model1_data2 0 0 -SOCS3 model1_data2 14.3117853821 20 -SOCS3 model1_data2 75.5899554372 40 -SOCS3 model1_data2 142.0469159486 60 -SOCS3 model1_data2 192.9222195204 80 -SOCS3 model1_data2 212.2654948088 90 -SOCS3 model1_data2 228.2361275238 100 -SOCS3 model1_data2 252.3148540949 120 -pSTAT5 model1_data2 0 0 -pSTAT5 model1_data2 9.8369693678 5 -pSTAT5 model1_data2 33.0656452021 10 -pSTAT5 model1_data2 54.527209543 15 -pSTAT5 model1_data2 70.5470742104 20 -pSTAT5 model1_data2 81.6623451946 25 -pSTAT5 model1_data2 89.0829820535 30 -pSTAT5 model1_data2 93.8642092334 35 -pSTAT5 model1_data2 96.7932901915 40 -pSTAT5 model1_data2 98.4294175031 45 -pSTAT5 model1_data2 99.1632089984 50 -pSTAT5 model1_data2 98.9293869832 60 -pSTAT5 model1_data2 97.4282678713 70 -pSTAT5 model1_data2 95.3294708838 80 -pSTAT5 model1_data2 92.9819600134 90 -pSTAT5 model1_data2 90.5750752559 100 -pSTAT5 model1_data2 85.9613665968 120 -RecSurf model1_data3 1.3 0 -RecSurf model1_data3 1.3964620975 10 -RecSurf model1_data3 1.3963221638 20 -RecSurf model1_data3 1.3947086697 30 -RecSurf model1_data3 1.3897823176 60 -RecSurf model1_data3 1.3848761993 90 -RecSurf model1_data3 1.3799892107 120 -IL13_cell model1_data3 0.8943932753 5 -IL13_cell model1_data3 1.4008696495 10 -IL13_cell model1_data3 1.7047650106 15 -IL13_cell model1_data3 1.9146632507 20 -IL13_cell model1_data3 2.2033843979 30 -IL13_cell model1_data3 2.397562842 40 -IL13_cell model1_data3 2.5330812121 50 -IL13_cell model1_data3 2.6282078445 60 -IL13_cell model1_data3 2.7417122581 80 -IL13_cell model1_data3 2.7970503617 100 -IL13_cell model1_data3 2.8234478969 120 -pIL4Ra model1_data3 0 0 -pIL4Ra model1_data3 0.2744955332 4 -pIL4Ra model1_data3 0.3216578772 5 -pIL4Ra model1_data3 0.3933567687 7 -pIL4Ra model1_data3 0.4597043427 10 -pIL4Ra model1_data3 0.5098622422 15 -pIL4Ra model1_data3 0.5209355598 17.5 -pIL4Ra model1_data3 0.5274474002 20 -pIL4Ra model1_data3 0.5312455475 22.5 -pIL4Ra model1_data3 0.5334322396 25 -pIL4Ra model1_data3 0.5353274577 30 -pIL4Ra model1_data3 0.5357859807 35 -pIL4Ra model1_data3 0.5357406973 40 -pIL4Ra model1_data3 0.5355190019 45 -pIL4Ra model1_data3 0.5352357244 50 -pIL4Ra model1_data3 0.5346192231 60 -pJAK2 model1_data3 0 0 -pJAK2 model1_data3 0.1344067902 2.5 -pJAK2 model1_data3 0.2642849089 4 -pJAK2 model1_data3 0.3526639874 5 -pJAK2 model1_data3 0.521188721 7 -pJAK2 model1_data3 0.5607467453 7.5 -pJAK2 model1_data3 0.7405410267 10 -pJAK2 model1_data3 0.8896091434 12.5 -pJAK2 model1_data3 1.0088202039 15 -pJAK2 model1_data3 1.1002654097 17.5 -pJAK2 model1_data3 1.1670068 20 -pJAK2 model1_data3 1.241456966 25 -pJAK2 model1_data3 1.2614818608 30 -pJAK2 model1_data3 1.2493256128 35 -pJAK2 model1_data3 1.2189568692 40 -pJAK2 model1_data3 1.1786213845 45 -pJAK2 model1_data3 1.1331778076 50 -pJAK2 model1_data3 1.0374903391 60 -pJAK2 model1_data3 0.8999485342 75 -pJAK2 model1_data3 0.7799605406 90 -pJAK2 model1_data3 0.6795218428 105 -pJAK2 model1_data3 0.5971065427 120 -pSTAT5 model1_data3 0 0 -pSTAT5 model1_data3 2.634483631 5 -pSTAT5 model1_data3 11.7531433701 10 -pSTAT5 model1_data3 24.2748997534 15 -pSTAT5 model1_data3 37.1275881585 20 -pSTAT5 model1_data3 48.5191839147 25 -pSTAT5 model1_data3 57.7724617566 30 -pSTAT5 model1_data3 64.8726802287 35 -pSTAT5 model1_data3 70.0862329678 40 -pSTAT5 model1_data3 73.7501381984 45 -pSTAT5 model1_data3 76.1821120513 50 -pSTAT5 model1_data3 78.3751652344 60 -pSTAT5 model1_data3 78.2340324455 70 -pSTAT5 model1_data3 76.7224653597 80 -pSTAT5 model1_data3 71.6980840069 100 -pSTAT5 model1_data3 65.7771184221 120 -RecSurf model1_data4 1.3 0 -RecSurf model1_data4 1.1049968747 10 -RecSurf model1_data4 1.0898045247 20 -RecSurf model1_data4 1.0774192011 30 -RecSurf model1_data4 1.041131316 60 -RecSurf model1_data4 1.0060657941 90 -RecSurf model1_data4 0.9721785729 120 -IL13_cell model1_data4 8.8441547846 5 -IL13_cell model1_data4 10.572248259 10 -IL13_cell model1_data4 11.0789193277 15 -IL13_cell model1_data4 11.218392462 20 -IL13_cell model1_data4 11.2025120759 30 -IL13_cell model1_data4 11.1076204284 40 -IL13_cell model1_data4 11.0040750003 50 -IL13_cell model1_data4 10.9005095881 60 -IL13_cell model1_data4 10.6965838267 80 -IL13_cell model1_data4 10.497236095 100 -IL13_cell model1_data4 10.3023831625 120 -SOCS3 model1_data4 0 0 -SOCS3 model1_data4 20.248449512 20 -SOCS3 model1_data4 87.1663276835 40 -SOCS3 model1_data4 153.238083014 60 -SOCS3 model1_data4 202.2629088523 80 -SOCS3 model1_data4 235.9720185864 100 -SOCS3 model1_data4 258.9746918774 120 +observableId preequilibrationConditionId simulationConditionId simulation time observableParameters noiseParameters observableTransformation noiseDistribution datasetId +observable_RecSurf model1_data1 1.3 0 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data1_RecSurf +observable_RecSurf model1_data1 1.427926991808253 10 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data1_RecSurf +observable_RecSurf model1_data1 1.4319385888479896 20 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data1_RecSurf +observable_RecSurf model1_data1 1.4320643864867446 30 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data1_RecSurf +observable_RecSurf model1_data1 1.4320684588992234 60 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data1_RecSurf +observable_RecSurf model1_data1 1.4320684590266992 90 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data1_RecSurf +observable_RecSurf model1_data1 1.43206845902619 120 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data1_RecSurf +observable_IL13_cell model1_data1 0.0 0 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data1_IL13_cell +observable_IL13_cell model1_data1 0.0 15 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data1_IL13_cell +observable_IL13_cell model1_data1 0.0 30 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data1_IL13_cell +observable_IL13_cell model1_data1 0.0 60 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data1_IL13_cell +observable_IL13_cell model1_data1 0.0 90 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data1_IL13_cell +observable_IL13_cell model1_data1 0.0 120 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data1_IL13_cell +observable_SOCS3mRNA model1_data1 0.0 0 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_SOCS3mRNA model1_data1 0.0 20 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_SOCS3mRNA model1_data1 0.0 30 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_SOCS3mRNA model1_data1 0.0 40 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_SOCS3mRNA model1_data1 0.0 60 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_SOCS3mRNA model1_data1 0.0 80 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_SOCS3mRNA model1_data1 0.0 90 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_SOCS3mRNA model1_data1 0.0 100 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_SOCS3mRNA model1_data1 0.0 120 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data1_SOCS3mRNA +observable_CD274mRNA model1_data1 0.0 30 scaling_CD274mRNA sd_CD274mRNA_abs;sd_CD274mRNA_rel lin normal model1_data1_CD274mRNA +observable_CD274mRNA model1_data1 0.0 60 scaling_CD274mRNA sd_CD274mRNA_abs;sd_CD274mRNA_rel lin normal model1_data1_CD274mRNA +observable_CD274mRNA model1_data1 0.0 90 scaling_CD274mRNA sd_CD274mRNA_abs;sd_CD274mRNA_rel lin normal model1_data1_CD274mRNA +observable_CD274mRNA model1_data1 0.0 120 scaling_CD274mRNA sd_CD274mRNA_abs;sd_CD274mRNA_rel lin normal model1_data1_CD274mRNA +observable_SOCS3 model1_data1 0.0 0 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data1_SOCS3 +observable_SOCS3 model1_data1 0.0 20 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data1_SOCS3 +observable_SOCS3 model1_data1 0.0 40 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data1_SOCS3 +observable_SOCS3 model1_data1 0.0 60 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data1_SOCS3 +observable_SOCS3 model1_data1 0.0 90 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data1_SOCS3 +observable_SOCS3 model1_data1 0.0 120 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data1_SOCS3 +observable_IL13_cell model1_data2 3.70243485187792 5 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.102602250106634 10 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.606176816690401 15 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.787190744501099 20 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.867222662178098 30 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.862577971260208 40 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.845608616412775 50 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.826855380847402 60 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.788996524746446 80 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.751439517867289 100 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_IL13_cell model1_data2 5.714238651665389 120 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data2_IL13_cell +observable_pIL4Ra model1_data2 0.0 0 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 1.2263705510795004 4 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 1.413757471717009 5 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 1.6865489839348096 7 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 1.9251310384231848 10 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 2.0946686038829796 15 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 2.149583279764929 20 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 2.167379337202789 30 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 2.160402799316903 40 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 2.155514247199555 45 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pIL4Ra model1_data2 2.1401400091498193 60 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data2_pIL4Ra +observable_pJAK2 model1_data2 0.0 0 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 0.9775090135462622 4 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.2102337502061185 5 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.55643711852321 7 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.8547032286290186 10 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 2.04118123737115 15 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 2.067824179111522 20 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 2.0361617107233565 25 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.9807981342609613 30 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.8462463471842605 40 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.7766690672545473 45 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.708475563062574 50 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.5799370097963468 60 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.36274659893853 80 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.1975862105125459 100 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_pJAK2 model1_data2 1.075080923283155 120 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data2_pJAK2 +observable_SOCS3mRNA model1_data2 0.0 0 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_SOCS3mRNA model1_data2 54.76422263520788 20 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_SOCS3mRNA model1_data2 122.30954485929658 30 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_SOCS3mRNA model1_data2 200.27989689561505 40 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_SOCS3mRNA model1_data2 364.8542817421903 60 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_SOCS3mRNA model1_data2 527.0847216592272 80 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_SOCS3mRNA model1_data2 605.5634998378023 90 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_SOCS3mRNA model1_data2 682.0514993897721 100 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_SOCS3mRNA model1_data2 829.1181151263846 120 scaling_SOCS3mRNA sd_SOCS3mRNA_abs;sd_SOCS3mRNA_rel lin normal model1_data2_SOCS3mRNA +observable_CD274mRNA model1_data2 0.2537652255615957 30 scaling_CD274mRNA sd_CD274mRNA_abs;sd_CD274mRNA_rel lin normal model1_data2_CD274mRNA +observable_CD274mRNA model1_data2 0.7569918538241007 60 scaling_CD274mRNA sd_CD274mRNA_abs;sd_CD274mRNA_rel lin normal model1_data2_CD274mRNA +observable_CD274mRNA model1_data2 1.2564101869971849 90 scaling_CD274mRNA sd_CD274mRNA_abs;sd_CD274mRNA_rel lin normal model1_data2_CD274mRNA +observable_CD274mRNA model1_data2 1.72023651747127 120 scaling_CD274mRNA sd_CD274mRNA_abs;sd_CD274mRNA_rel lin normal model1_data2_CD274mRNA +observable_SOCS3 model1_data2 0.0 0 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data2_SOCS3 +observable_SOCS3 model1_data2 14.311803811021125 20 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data2_SOCS3 +observable_SOCS3 model1_data2 75.58996639105979 40 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data2_SOCS3 +observable_SOCS3 model1_data2 142.04692087035627 60 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data2_SOCS3 +observable_SOCS3 model1_data2 192.92224880264308 80 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data2_SOCS3 +observable_SOCS3 model1_data2 212.26555835074686 90 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data2_SOCS3 +observable_SOCS3 model1_data2 228.23619464817077 100 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data2_SOCS3 +observable_SOCS3 model1_data2 252.31489068281527 120 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data2_SOCS3 +observable_pSTAT5 model1_data2 0.0 0 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 9.83696908739854 5 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 33.06562649345129 10 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 54.52720009429548 15 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 70.54705569765059 20 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 81.66234681955419 25 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 89.08297754812236 30 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 93.86421025509601 35 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 96.79329591396666 40 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 98.42942572285993 45 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 99.16321780420404 50 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 98.92939346617315 60 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 97.42826911241804 70 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 95.32946389492542 80 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 92.98193745496619 90 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 90.57504971247687 100 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_pSTAT5 model1_data2 85.96134731553998 120 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data2_pSTAT5 +observable_RecSurf model1_data3 1.3 0 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data3_RecSurf +observable_RecSurf model1_data3 1.396462100259517 10 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data3_RecSurf +observable_RecSurf model1_data3 1.396322171155627 20 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data3_RecSurf +observable_RecSurf model1_data3 1.3947086687227774 30 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data3_RecSurf +observable_RecSurf model1_data3 1.389782317398023 60 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data3_RecSurf +observable_RecSurf model1_data3 1.3848761990152654 90 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data3_RecSurf +observable_RecSurf model1_data3 1.3799892103568623 120 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data3_RecSurf +observable_IL13_cell model1_data3 0.8943932743073547 5 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 1.40086966736291 10 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 1.704765175993059 15 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 1.9146636085914057 20 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 2.203384354718069 30 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 2.3975627838542746 40 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 2.533081450413838 50 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 2.628207921587208 60 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 2.741713850921113 80 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 2.797053241049496 100 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_IL13_cell model1_data3 2.8234503684628374 120 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data3_IL13_cell +observable_pIL4Ra model1_data3 0.0 0 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.2744955361452215 4 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.3216578765651934 5 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.39335677856917906 7 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.45970435218137606 10 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5098623300755035 15 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5209357403426477 17.5 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5274475864948982 20 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5312457044727048 22.5 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5334323595580074 25 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5353274272019388 30 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5357859091515362 35 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5357406675068845 40 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5355190602169534 45 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.535235844323706 50 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pIL4Ra model1_data3 0.5346192505068957 60 scaling_pIL4Ra sd_pIL4Ra_abs;sd_pIL4Ra_rel lin normal model1_data3_pIL4Ra +observable_pJAK2 model1_data3 0.0 0 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.1344067630426549 2.5 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.26428491203471793 4 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.35266396027701236 5 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.5211886803349022 7 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.5607467123341389 7.5 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.7405410107564824 10 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.8896091296515969 12.5 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.008820151880419 15 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.1002652576108447 17.5 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.1670065800687508 20 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.2414567532114642 25 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.2614816212828381 30 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.2493251950844853 35 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.2189564659375824 40 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.1786215213433715 45 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.1331782950408023 50 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 1.0374905773437633 60 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.8999493222200821 75 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.7799631825623071 90 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.6795245688432037 105 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pJAK2 model1_data3 0.5971088131766777 120 scaling_pJAK2 sd_pJAK2_abs;sd_pJAK2_rel lin normal model1_data3_pJAK2 +observable_pSTAT5 model1_data3 0.0 0 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 2.6344837045638383 5 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 11.753143123803058 10 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 24.274895761901043 15 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 37.1275678656001 20 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 48.51915536341248 25 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 57.77245090523443 30 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 64.87268609561487 35 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 70.08623714198566 40 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 73.75011775813557 45 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 76.18206463993167 50 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 78.37513831460014 60 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 78.23401987966972 70 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 76.72268279582025 80 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 71.69845545903121 100 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_pSTAT5 model1_data3 65.77744144397786 120 sd_pSTAT5_abs;sd_pSTAT5_rel lin normal model1_data3_pSTAT5 +observable_RecSurf model1_data4 1.3 0 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data4_RecSurf +observable_RecSurf model1_data4 1.104996842564384 10 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data4_RecSurf +observable_RecSurf model1_data4 1.089804529700224 20 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data4_RecSurf +observable_RecSurf model1_data4 1.0774191998292082 30 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data4_RecSurf +observable_RecSurf model1_data4 1.0411313159369644 60 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data4_RecSurf +observable_RecSurf model1_data4 1.006065794219118 90 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data4_RecSurf +observable_RecSurf model1_data4 0.9721785730455508 120 sd_RecSurf_abs;sd_RecSurf_rel lin normal model1_data4_RecSurf +observable_IL13_cell model1_data4 8.844157651297358 5 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 10.572248762935684 10 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 11.078919386833286 15 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 11.218392512716926 20 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 11.202512843128465 30 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 11.10762120330836 40 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 11.004075298162057 50 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 10.900509979762443 60 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 10.696583841810686 80 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 10.497236097510338 100 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_IL13_cell model1_data4 10.302383164662874 120 scaling_IL13_cell sd_IL13_cell_abs;sd_IL13_cell_rel lin normal model1_data4_IL13_cell +observable_SOCS3 model1_data4 0.0 0 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data4_SOCS3 +observable_SOCS3 model1_data4 20.24844603287298 20 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data4_SOCS3 +observable_SOCS3 model1_data4 87.16633006547572 40 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data4_SOCS3 +observable_SOCS3 model1_data4 153.23804436505284 60 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data4_SOCS3 +observable_SOCS3 model1_data4 202.26285995257064 80 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data4_SOCS3 +observable_SOCS3 model1_data4 235.97201041152738 100 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data4_SOCS3 +observable_SOCS3 model1_data4 258.9747149860635 120 sd_SOCS3_abs;sd_SOCS3_rel lin normal model1_data4_SOCS3 diff --git a/problems/Sneyd_PNAS2002/v1/simulations.tsv b/problems/Sneyd_PNAS2002/v1/simulations.tsv index 79f93e2..c544774 100644 --- a/problems/Sneyd_PNAS2002/v1/simulations.tsv +++ b/problems/Sneyd_PNAS2002/v1/simulations.tsv @@ -1,136 +1,136 @@ observableId preequilibrationConditionId simulationConditionId simulation time observableParameters noiseParameters experimentName replicateId useData datasetId -open_probability Ca_dose_response__1 0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.121894546523477 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.060595553808957 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.029927743627544 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.016966738060837 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.010950865102333 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.007889935956002 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.006208795803398 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.00522799579081 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.004628767636314 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.004249773944653 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.004003778690146 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.003840913784634 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.003731366618313 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__1 0.003656677446066 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability -open_probability Ca_dose_response__2 0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.215678142415106 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.163761426885113 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.102217430277337 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.067586627905053 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.04794160008511 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.036246811779277 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.028958334975966 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.024232259124856 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.021063632687336 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.018879468210961 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.017339073625141 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.016231996423034 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.015423728256309 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__2 0.014825697161151 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability -open_probability Ca_dose_response__3 0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.261822224490706 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.243214273475024 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.165452868159381 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.114719898954169 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.083539032274217 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.063834828747858 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.05094768692273 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.042247387361814 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.036207087269719 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.031910713745902 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.028790694098721 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.02648455706322 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.02475422564705 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__3 0.023439256475873 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability -open_probability Ca_dose_response__4 0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.256421638211286 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.244049602963311 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.157567043658913 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.102262809203666 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.069922277704295 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.050522181826376 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.038429952523923 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.030609970408551 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.02538346521554 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.021788797300514 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.019255261437112 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.017432484512352 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.016098394582075 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__4 0.015108032006753 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability -open_probability Ca_dose_response__5 0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.209956782778307 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.171912802309381 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.091220598909618 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.049356198337219 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.029091174010564 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.018788457182827 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.013206212177869 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.00999556752894 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.008051163083109 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.006822135884553 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.006018101069233 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.005477684256377 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.00510679643968 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__5 0.004848188811793 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability -open_probability Ca_dose_response__6 0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.227499981859172 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.198777336708334 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.113821705477149 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.065924070834603 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.040993686128187 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.027509842618924 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.019820431596413 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.01520884723014 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.012317850790703 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.01043614698577 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.009172808913423 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.008303103892224 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.007692317288332 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability Ca_dose_response__6 0.007256603205075 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability -open_probability IP3_dose_response__3 0 0 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.261822224490706 0.07 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.243214273475024 0.14 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.165452868159381 0.21 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.114719898954169 0.28 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.083539032274217 0.35 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.063834828747858 0.42 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.05094768692273 0.49 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.042247387361814 0.56 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.036207087269719 0.63 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.031910713745902 0.7 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.028790694098721 0.77 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.02648455706322 0.84 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.02475422564705 0.91 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__3 0.023439256475873 0.98 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability -open_probability IP3_dose_response__1 0 0 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.027513716704193 0.07 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.099307231943202 0.14 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.130202341702809 0.21 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.122285020707863 0.28 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.101303258567466 0.35 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.080710796039658 0.42 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.064352347846962 0.49 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.052281488561359 0.56 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.043582860721469 0.63 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.037326744571104 0.7 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.032792900371487 0.77 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.029469364593807 0.84 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.027002522397321 0.91 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__1 0.025149254710067 0.98 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability -open_probability IP3_dose_response__2 0 0 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.093722639361853 0.07 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.190123164511576 0.14 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.17175740987611 0.21 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.129468384266291 0.28 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.095441173133522 0.35 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.072142226375651 0.42 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.05661310471373 0.49 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.046149533503429 0.56 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.038946262778702 0.63 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.033872579795436 0.7 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.03022216500319 0.77 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.027546187017617 0.84 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.025552684613735 0.91 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability -open_probability IP3_dose_response__2 0.024047022739061 0.98 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability Ca_dose_response__1 0.0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.12189460915173836 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.060595600126932575 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.029927747690899155 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.016966738184186755 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.010950865016580569 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.00788993497917522 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.006208793678784985 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.005227993716165281 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.004628765872477415 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.004249772507970916 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.004003775559654114 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.003840909956038643 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.0037313630748248743 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__1 0.0036566744017752094 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__1_open_probability +open_probability Ca_dose_response__2 0.0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.2156783939883289 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.1637614891619114 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.10221748009569213 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.06758663128322337 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.04794160095064292 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.036246811756707686 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.02895833452169648 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.024232254002516274 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.02106362574537538 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.018879461030966715 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.01733906706469798 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.016231990638657746 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.015423722602488974 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__2 0.014825686310077113 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__2_open_probability +open_probability Ca_dose_response__3 0.0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.2618225025935463 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.24321444278325874 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.1654529503356218 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.11471991304692097 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.08353903388654797 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.06383482928345324 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.05094768699926752 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.042247385778450136 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.036207085125253335 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.03191071148988078 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.02879068724118109 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.02648454614961488 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.024754214888953425 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__3 0.023439245751075994 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__3_open_probability +open_probability Ca_dose_response__4 0.0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.2564225786499537 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.24404998252690585 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.15756717917046456 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.10226283989199549 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.0699222820429615 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.05052218348324393 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.03842995291531829 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.03060996965934795 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.025383461604882435 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.021788793547349455 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.019255257861479427 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.01743247528761651 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.016098378686154265 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__4 0.015108016535030223 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__4_open_probability +open_probability Ca_dose_response__5 0.0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.2275002081564284 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.19877746111460623 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.1138218314343141 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.0659241477807292 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.040993698203914665 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.0275098457918434 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.01982043274444511 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.015208845183712684 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.012317836689914867 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.010436121509725577 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.009172784861281806 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.008303081521988904 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.00769229724467487 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__5 0.007256568219058782 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__5_open_probability +open_probability Ca_dose_response__6 0.0 0 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.2099567704552069 0.07 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.17191308059998966 0.14 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.09122077319433003 0.21 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.0493564717388131 0.28 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.029091210122601234 0.35 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.01878846041346061 0.42 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.013206212136100176 0.49 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.009995563352867354 0.56 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.00805114833223848 0.63 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.0068221220281195856 0.7 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.006018088811625641 0.77 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.005477673976590076 0.84 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.005106787345759894 0.91 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability Ca_dose_response__6 0.004848173616728174 0.98 0.022665679544462 Ca^{2+} response 1 TRUE Ca_dose_response__6_open_probability +open_probability IP3_dose_response__1 0.0 0 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.027513671263886486 0.07 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.09930732855326843 0.14 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.13020255378899842 0.21 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.12228519139539264 0.28 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.1013033617652879 0.35 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.080710851428122 0.42 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.06435237669477711 0.49 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.05228152505352381 0.56 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.0435828851196742 0.63 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.03732675856308595 0.7 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.032792907790655974 0.77 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.029469368282055822 0.84 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.027002524036249757 0.91 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__1 0.025149255284731435 0.98 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__3_open_probability +open_probability IP3_dose_response__2 0.0 0 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.09372223757657416 0.07 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.19012287720246318 0.14 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.17175743779599476 0.21 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.12946841801585346 0.28 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.09544099532473556 0.35 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.07214208802881261 0.42 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.05661304979415705 0.49 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.04614951797350116 0.56 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.038946261606131266 0.63 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.033872583449151325 0.7 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.03022216922898188 0.77 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.02754619052835453 0.84 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.025552686467794135 0.91 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__2 0.024047023208516195 0.98 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__1_open_probability +open_probability IP3_dose_response__3 0.0 0 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.2618225025935463 0.07 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.24321444278325874 0.14 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.1654529503356218 0.21 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.11471991304692097 0.28 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.08353903388654797 0.35 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.06383482928345324 0.42 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.05094768699926752 0.49 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.042247385778450136 0.56 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.036207085125253335 0.63 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.03191071148988078 0.7 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.02879068724118109 0.77 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.02648454614961488 0.84 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.024754214888953425 0.91 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability +open_probability IP3_dose_response__3 0.023439245751075994 0.98 0.022665679544462 IP_3 response 1 TRUE IP3_dose_response__2_open_probability diff --git a/problems/Zhao_QuantBiol2020/v1/simulations.tsv b/problems/Zhao_QuantBiol2020/v1/simulations.tsv index f92843c..6c2cee4 100644 --- a/problems/Zhao_QuantBiol2020/v1/simulations.tsv +++ b/problems/Zhao_QuantBiol2020/v1/simulations.tsv @@ -9,25 +9,6 @@ observable_confirmed_infected model1_China_Stage_I 6751.446607931774 36 sd_con observable_confirmed_infected model1_China_Stage_I 7530.370199284482 37 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I observable_confirmed_infected model1_China_Stage_I 8393.869639818662 38 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I observable_confirmed_infected model1_China_Stage_I 9351.054020134636 39 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 10412.017063902333 40 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 11587.943145064462 41 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 12891.225172772729 42 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 14335.594720520885 43 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 15936.266717096447 44 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 17710.09916143024 45 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 19675.77070432931 46 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 21853.97666262693 47 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 24267.646952721356 48 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 26942.186635497943 49 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 29905.743348278025 50 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 33189.50246999955 51 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 36828.01526089957 52 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 40859.56101049569 53 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 45326.549616733195 54 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 50275.96585781884 55 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 55759.86322437042 56 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 61835.90884911595 57 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I -observable_confirmed_infected model1_China_Stage_I 68567.98916666959 58 sd_confirmed_infected_China_Stage_I model1_data_observable_confirmed_infected_China_Stage_I observable_confirmed_infected model1_China_Stage_II 4000.0 0 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II observable_confirmed_infected model1_China_Stage_II 4529.955981156226 1 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II observable_confirmed_infected model1_China_Stage_II 5183.766817497703 2 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II @@ -43,14 +24,6 @@ observable_confirmed_infected model1_China_Stage_II 10391.598465497258 11 sd_c observable_confirmed_infected model1_China_Stage_II 10720.151623671345 12 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II observable_confirmed_infected model1_China_Stage_II 11004.610020621114 13 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II observable_confirmed_infected model1_China_Stage_II 11249.610740921637 14 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II -observable_confirmed_infected model1_China_Stage_II 11459.672285606992 15 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II -observable_confirmed_infected model1_China_Stage_II 11639.061868635077 16 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II -observable_confirmed_infected model1_China_Stage_II 11791.719524289767 17 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II -observable_confirmed_infected model1_China_Stage_II 11921.221794098255 18 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II -observable_confirmed_infected model1_China_Stage_II 12030.772288564198 19 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II -observable_confirmed_infected model1_China_Stage_II 12123.210073419554 20 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II -observable_confirmed_infected model1_China_Stage_II 12201.029172878409 21 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II -observable_confirmed_infected model1_China_Stage_II 12266.404461231356 22 sd_confirmed_infected_China_Stage_II model1_data_observable_confirmed_infected_China_Stage_II observable_confirmed_infected model1_Hubei_Stage_I 339.9306290483404 15 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I observable_confirmed_infected model1_Hubei_Stage_I 443.2797002209989 16 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I observable_confirmed_infected model1_Hubei_Stage_I 575.8823423744068 17 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I @@ -61,25 +34,6 @@ observable_confirmed_infected model1_Hubei_Stage_I 1600.319314024311 21 sd_con observable_confirmed_infected model1_Hubei_Stage_I 2057.933024086237 22 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I observable_confirmed_infected model1_Hubei_Stage_I 2643.6936397547756 23 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I observable_confirmed_infected model1_Hubei_Stage_I 3393.349887929675 24 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 4352.593730170196 25 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 5579.8047107869825 26 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 7149.537984791677 27 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 9156.94884711046 28 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 11723.392573762732 29 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 15003.488011322157 30 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 19193.990577985784 31 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 24544.88395893585 32 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 31373.134555171426 33 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 40079.62210548101 34 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 51169.713641480994 35 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 65277.893016540984 36 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 83196.6424813204 37 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 105909.38134167925 38 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 134626.57973130292 39 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 170823.19604684066 40 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 216274.1242115494 41 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 273082.697433498 42 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I -observable_confirmed_infected model1_Hubei_Stage_I 343695.43638098857 43 sd_confirmed_infected_Hubei_Stage_I model1_data_observable_confirmed_infected_Hubei_Stage_I observable_confirmed_infected model1_Hubei_Stage_II 1600.0 0 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II observable_confirmed_infected model1_Hubei_Stage_II 2095.8511448870468 1 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II observable_confirmed_infected model1_Hubei_Stage_II 2905.487013487504 2 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II @@ -95,16 +49,6 @@ observable_confirmed_infected model1_Hubei_Stage_II 11954.455962712012 11 sd_c observable_confirmed_infected model1_Hubei_Stage_II 12664.148143198008 12 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II observable_confirmed_infected model1_Hubei_Stage_II 13298.96225437696 13 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II observable_confirmed_infected model1_Hubei_Stage_II 13863.45029444149 14 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 14362.850318149167 15 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 14802.709468093912 16 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 15188.61753663063 17 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 15526.02327020389 18 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 15820.114419319407 19 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 16075.743094330013 20 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 16297.385313284769 21 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 16489.124789776582 22 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 16654.65382288976 23 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II -observable_confirmed_infected model1_Hubei_Stage_II 16797.28571110865 24 sd_confirmed_infected_Hubei_Stage_II model1_data_observable_confirmed_infected_Hubei_Stage_II observable_confirmed_infected model1_Wuhan_Stage_I 623.4894980636154 15 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I observable_confirmed_infected model1_Wuhan_Stage_I 729.5145100718623 16 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I observable_confirmed_infected model1_Wuhan_Stage_I 863.8288416489295 17 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I @@ -115,25 +59,6 @@ observable_confirmed_infected model1_Wuhan_Stage_I 1864.3495712770527 21 sd_co observable_confirmed_infected model1_Wuhan_Stage_I 2298.3423623079566 22 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I observable_confirmed_infected model1_Wuhan_Stage_I 2846.3334462080397 23 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I observable_confirmed_infected model1_Wuhan_Stage_I 3537.9890554868725 24 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 4410.592086206255 25 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 5510.934174793033 26 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 6897.640951977852 27 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 8644.00814811753 28 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 10841.42758864212 29 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 13603.474292999217 30 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 17070.700777461898 31 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 21416.141991943306 32 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 26851.450247184606 33 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 33633.453148678906 34 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 42070.75073767001 35 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 52529.72589265236 36 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 65439.06864887752 37 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 81291.63442739107 38 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 100642.27491158429 39 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 124100.26327833798 40 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 152315.28944679696 41 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 185956.6993148903 42 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I -observable_confirmed_infected model1_Wuhan_Stage_I 225686.74933692656 43 sd_confirmed_infected_Wuhan_Stage_I model1_data_observable_confirmed_infected_Wuhan_Stage_I observable_confirmed_infected model1_Wuhan_Stage_II 2000.0 0 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II observable_confirmed_infected model1_Wuhan_Stage_II 2182.387259854863 1 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II observable_confirmed_infected model1_Wuhan_Stage_II 2692.208036291985 2 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II @@ -149,16 +74,6 @@ observable_confirmed_infected model1_Wuhan_Stage_II 15278.999982177762 11 sd_c observable_confirmed_infected model1_Wuhan_Stage_II 17053.319255539798 12 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II observable_confirmed_infected model1_Wuhan_Stage_II 18835.417273867417 13 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II observable_confirmed_infected model1_Wuhan_Stage_II 20613.975248096172 14 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 22379.367775519644 15 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 24123.467344653847 16 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 25839.46980677376 17 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 27521.738403806954 18 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 29165.662805258216 19 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 30767.534172513682 20 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 32324.432448324344 21 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 33834.128381828545 22 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 35294.99092651035 23 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II -observable_confirmed_infected model1_Wuhan_Stage_II 36705.91051995219 24 sd_confirmed_infected_Wuhan_Stage_II model1_data_observable_confirmed_infected_Wuhan_Stage_II observable_confirmed_infected model1_Wuhan_Stage_III 36000.0 0 sd_confirmed_infected_Wuhan_Stage_III model1_data_observable_confirmed_infected_Wuhan_Stage_III observable_confirmed_infected model1_Wuhan_Stage_III 37698.832088516756 1 sd_confirmed_infected_Wuhan_Stage_III model1_data_observable_confirmed_infected_Wuhan_Stage_III observable_confirmed_infected model1_Wuhan_Stage_III 39423.646390452326 2 sd_confirmed_infected_Wuhan_Stage_III model1_data_observable_confirmed_infected_Wuhan_Stage_III @@ -166,5 +81,3 @@ observable_confirmed_infected model1_Wuhan_Stage_III 41031.43409166907 3 sd_co observable_confirmed_infected model1_Wuhan_Stage_III 42455.93798575727 4 sd_confirmed_infected_Wuhan_Stage_III model1_data_observable_confirmed_infected_Wuhan_Stage_III observable_confirmed_infected model1_Wuhan_Stage_III 43676.24018030864 5 sd_confirmed_infected_Wuhan_Stage_III model1_data_observable_confirmed_infected_Wuhan_Stage_III observable_confirmed_infected model1_Wuhan_Stage_III 44696.824044238994 6 sd_confirmed_infected_Wuhan_Stage_III model1_data_observable_confirmed_infected_Wuhan_Stage_III -observable_confirmed_infected model1_Wuhan_Stage_III 45535.17671905029 7 sd_confirmed_infected_Wuhan_Stage_III model1_data_observable_confirmed_infected_Wuhan_Stage_III -observable_confirmed_infected model1_Wuhan_Stage_III 46214.29041199827 8 sd_confirmed_infected_Wuhan_Stage_III model1_data_observable_confirmed_infected_Wuhan_Stage_III diff --git a/problems/Zheng_PNAS2012/v1/simulations.tsv b/problems/Zheng_PNAS2012/v1/simulations.tsv index c80d6c8..931d307 100644 --- a/problems/Zheng_PNAS2012/v1/simulations.tsv +++ b/problems/Zheng_PNAS2012/v1/simulations.tsv @@ -1,61 +1,61 @@ observableId preequilibrationConditionId simulationConditionId simulation time observableParameters noiseParameters -observable_K27me0K36me0 preequilibration simCondition 0.00431 0 0.002339466852399 -observable_K27me0K36me0 preequilibration simCondition 0.00093 5 0.002339466852399 -observable_K27me0K36me0 preequilibration simCondition 0.00051 10 0.002339466852399 -observable_K27me0K36me0 preequilibration simCondition 0.00054 25 0.002339466852399 -observable_K27me0K36me1 preequilibration simCondition 0.00789 0 0.002339466852399 -observable_K27me0K36me1 preequilibration simCondition 0.00499 5 0.002339466852399 -observable_K27me0K36me1 preequilibration simCondition 0.00308 10 0.002339466852399 -observable_K27me0K36me1 preequilibration simCondition 0.00131 25 0.002339466852399 -observable_K27me1K36me0 preequilibration simCondition 0.00216 0 0.002339466852399 -observable_K27me1K36me0 preequilibration simCondition 0.00159 5 0.002339466852399 -observable_K27me1K36me0 preequilibration simCondition 0.00123 10 0.002339466852399 -observable_K27me1K36me0 preequilibration simCondition 0.00091 25 0.002339466852399 -observable_K27me0K36me2 preequilibration simCondition 0.16777 0 0.002339466852399 -observable_K27me0K36me2 preequilibration simCondition 0.14469 5 0.002339466852399 -observable_K27me0K36me2 preequilibration simCondition 0.1214 10 0.002339466852399 -observable_K27me0K36me2 preequilibration simCondition 0.05789 25 0.002339466852399 -observable_K27me1K36me1 preequilibration simCondition 0.00908 0 0.002339466852399 -observable_K27me1K36me1 preequilibration simCondition 0.00724 5 0.002339466852399 -observable_K27me1K36me1 preequilibration simCondition 0.00619 10 0.002339466852399 -observable_K27me1K36me1 preequilibration simCondition 0.00323 25 0.002339466852399 -observable_K27me2K36me0 preequilibration simCondition 0.00623 0 0.002339466852399 -observable_K27me2K36me0 preequilibration simCondition 0.00684 5 0.002339466852399 -observable_K27me2K36me0 preequilibration simCondition 0.00623 10 0.002339466852399 -observable_K27me2K36me0 preequilibration simCondition 0.00609 25 0.002339466852399 -observable_K27me0K36me3 preequilibration simCondition 0.04922 0 0.002339466852399 -observable_K27me0K36me3 preequilibration simCondition 0.05666 5 0.002339466852399 -observable_K27me0K36me3 preequilibration simCondition 0.06029 10 0.002339466852399 -observable_K27me0K36me3 preequilibration simCondition 0.05922 25 0.002339466852399 -observable_K27me1K36me2 preequilibration simCondition 0.59615 0 0.002339466852399 -observable_K27me1K36me2 preequilibration simCondition 0.60752 5 0.002339466852399 -observable_K27me1K36me2 preequilibration simCondition 0.61758 10 0.002339466852399 -observable_K27me1K36me2 preequilibration simCondition 0.6578 25 0.002339466852399 -observable_K27me2K36me1 preequilibration simCondition 0.01362 0 0.002339466852399 -observable_K27me2K36me1 preequilibration simCondition 0.01367 5 0.002339466852399 -observable_K27me2K36me1 preequilibration simCondition 0.01347 10 0.002339466852399 -observable_K27me2K36me1 preequilibration simCondition 0.0131 25 0.002339466852399 -observable_K27me3K36me0 preequilibration simCondition 0.00285 0 0.002339466852399 -observable_K27me3K36me0 preequilibration simCondition 0.00309 5 0.002339466852399 -observable_K27me3K36me0 preequilibration simCondition 0.00365 10 0.002339466852399 -observable_K27me3K36me0 preequilibration simCondition 0.00398 25 0.002339466852399 -observable_K27me1K36me3 preequilibration simCondition 0.10672 0 0.002339466852399 -observable_K27me1K36me3 preequilibration simCondition 0.11679 5 0.002339466852399 -observable_K27me1K36me3 preequilibration simCondition 0.1198 10 0.002339466852399 -observable_K27me1K36me3 preequilibration simCondition 0.14836 25 0.002339466852399 -observable_K27me2K36me2 preequilibration simCondition 0.02539 0 0.002339466852399 -observable_K27me2K36me2 preequilibration simCondition 0.02709 5 0.002339466852399 -observable_K27me2K36me2 preequilibration simCondition 0.03716 10 0.002339466852399 -observable_K27me2K36me2 preequilibration simCondition 0.03508 25 0.002339466852399 -observable_K27me3K36me1 preequilibration simCondition 0.00223 0 0.002339466852399 -observable_K27me3K36me1 preequilibration simCondition 0.00263 5 0.002339466852399 -observable_K27me3K36me1 preequilibration simCondition 0.00255 10 0.002339466852399 -observable_K27me3K36me1 preequilibration simCondition 0.00312 25 0.002339466852399 -observable_K27me2K36me3 preequilibration simCondition 0.00527 0 0.002339466852399 -observable_K27me2K36me3 preequilibration simCondition 0.00483 5 0.002339466852399 -observable_K27me2K36me3 preequilibration simCondition 0.00575 10 0.002339466852399 -observable_K27me2K36me3 preequilibration simCondition 0.00747 25 0.002339466852399 -observable_K27me3K36me2 preequilibration simCondition 0.00112 0 0.002339466852399 -observable_K27me3K36me2 preequilibration simCondition 0.00148 5 0.002339466852399 -observable_K27me3K36me2 preequilibration simCondition 0.00112 10 0.002339466852399 -observable_K27me3K36me2 preequilibration simCondition 0.00186 25 0.002339466852399 +observable_K27me0K36me0 preequilibration simCondition 0.004355000621466505 0 0.002339466852399 +observable_K27me0K36me0 preequilibration simCondition 0.0010406606046242238 5 0.002339466852399 +observable_K27me0K36me0 preequilibration simCondition 0.0008480413586166465 10 0.002339466852399 +observable_K27me0K36me0 preequilibration simCondition 0.00045913688093672566 25 0.002339466852399 +observable_K27me0K36me1 preequilibration simCondition 0.008990149994142495 0 0.002339466852399 +observable_K27me0K36me1 preequilibration simCondition 0.0021632893703798753 5 0.002339466852399 +observable_K27me0K36me1 preequilibration simCondition 0.0017628791556048675 10 0.002339466852399 +observable_K27me0K36me1 preequilibration simCondition 0.0009544379822149629 25 0.002339466852399 +observable_K27me1K36me0 preequilibration simCondition 0.0034012018195000654 0 0.002339466852399 +observable_K27me1K36me0 preequilibration simCondition 0.0016757444267071913 5 0.002339466852399 +observable_K27me1K36me0 preequilibration simCondition 0.0010282074869428404 10 0.002339466852399 +observable_K27me1K36me0 preequilibration simCondition 0.00047381122326452295 25 0.002339466852399 +observable_K27me0K36me2 preequilibration simCondition 0.17128337700623167 0 0.002339466852399 +observable_K27me0K36me2 preequilibration simCondition 0.1427518274390196 5 0.002339466852399 +observable_K27me0K36me2 preequilibration simCondition 0.11632980253993179 10 0.002339466852399 +observable_K27me0K36me2 preequilibration simCondition 0.06298267285902262 25 0.002339466852399 +observable_K27me1K36me1 preequilibration simCondition 0.007349350139399694 0 0.002339466852399 +observable_K27me1K36me1 preequilibration simCondition 0.005984716232582298 5 0.002339466852399 +observable_K27me1K36me1 preequilibration simCondition 0.006004601343887349 10 0.002339466852399 +observable_K27me1K36me1 preequilibration simCondition 0.006125938242368225 25 0.002339466852399 +observable_K27me2K36me0 preequilibration simCondition 0.00731756350995332 0 0.002339466852399 +observable_K27me2K36me0 preequilibration simCondition 0.007205638670620441 5 0.002339466852399 +observable_K27me2K36me0 preequilibration simCondition 0.00626949176325535 10 0.002339466852399 +observable_K27me2K36me0 preequilibration simCondition 0.004708427482679459 25 0.002339466852399 +observable_K27me0K36me3 preequilibration simCondition 0.04777974935476079 0 0.002339466852399 +observable_K27me0K36me3 preequilibration simCondition 0.05390250146894021 5 0.002339466852399 +observable_K27me0K36me3 preequilibration simCondition 0.058006188446400306 10 0.002339466852399 +observable_K27me0K36me3 preequilibration simCondition 0.06470962823682007 25 0.002339466852399 +observable_K27me1K36me2 preequilibration simCondition 0.5933651283229397 0 0.002339466852399 +observable_K27me1K36me2 preequilibration simCondition 0.6092954502679464 5 0.002339466852399 +observable_K27me1K36me2 preequilibration simCondition 0.6214756291686819 10 0.002339466852399 +observable_K27me1K36me2 preequilibration simCondition 0.6549598259287452 25 0.002339466852399 +observable_K27me2K36me1 preequilibration simCondition 0.011600614336826142 0 0.002339466852399 +observable_K27me2K36me1 preequilibration simCondition 0.01303612530732943 5 0.002339466852399 +observable_K27me2K36me1 preequilibration simCondition 0.013925527080183847 10 0.002339466852399 +observable_K27me2K36me1 preequilibration simCondition 0.014891445593152057 25 0.002339466852399 +observable_K27me3K36me0 preequilibration simCondition 0.0035378388166489297 0 0.002339466852399 +observable_K27me3K36me0 preequilibration simCondition 0.003865046870513472 5 0.002339466852399 +observable_K27me3K36me0 preequilibration simCondition 0.003628653664461577 10 0.002339466852399 +observable_K27me3K36me0 preequilibration simCondition 0.0026636761958030693 25 0.002339466852399 +observable_K27me1K36me3 preequilibration simCondition 0.10481779620119801 0 0.002339466852399 +observable_K27me1K36me3 preequilibration simCondition 0.11824824925573045 5 0.002339466852399 +observable_K27me1K36me3 preequilibration simCondition 0.12724984815251336 10 0.002339466852399 +observable_K27me1K36me3 preequilibration simCondition 0.14195431664579958 25 0.002339466852399 +observable_K27me2K36me2 preequilibration simCondition 0.027204523487223582 0 0.002339466852399 +observable_K27me2K36me2 preequilibration simCondition 0.030570520098447514 5 0.002339466852399 +observable_K27me2K36me2 preequilibration simCondition 0.03265598939894844 10 0.002339466852399 +observable_K27me2K36me2 preequilibration simCondition 0.034920817728722506 25 0.002339466852399 +observable_K27me3K36me1 preequilibration simCondition 0.0025911145563867785 0 0.002339466852399 +observable_K27me3K36me1 preequilibration simCondition 0.002947278115520194 5 0.002339466852399 +observable_K27me3K36me1 preequilibration simCondition 0.002971712981545496 10 0.002339466852399 +observable_K27me3K36me1 preequilibration simCondition 0.0022284651784815765 25 0.002339466852399 +observable_K27me2K36me3 preequilibration simCondition 0.005025117549690502 0 0.002339466852399 +observable_K27me2K36me3 preequilibration simCondition 0.0057212630889061705 5 0.002339466852399 +observable_K27me2K36me3 preequilibration simCondition 0.006174738426115336 10 0.002339466852399 +observable_K27me2K36me3 preequilibration simCondition 0.0066841923473993144 25 0.002339466852399 +observable_K27me3K36me2 preequilibration simCondition 0.0013814742836317387 0 0.002339466852399 +observable_K27me3K36me2 preequilibration simCondition 0.0015916887827325057 5 0.002339466852399 +observable_K27me3K36me2 preequilibration simCondition 0.0016686890329107155 10 0.002339466852399 +observable_K27me3K36me2 preequilibration simCondition 0.001283207474590104 25 0.002339466852399 diff --git a/src/python/simulate.py b/src/python/simulate.py index e867a20..47dd071 100755 --- a/src/python/simulate.py +++ b/src/python/simulate.py @@ -3,23 +3,63 @@ Script to simulate a model using AMICI. Basic usage: simulate.py +Use ``--check-simulations`` to compare the simulations against the +simulation table of the problem (``v1/simulations.tsv``); the script then +exits with a non-zero status if they differ. See --help for more options. """ +import copy import os +import sys import argparse import benchmark_models_petab import amici.sim.sundials as ass -from amici.importers.petab.v1 import ( - import_petab_problem, +from amici.importers.petab.v1 import import_petab_problem +from amici.sim.sundials.petab.v1 import ( + rdatas_to_simulation_df, simulate_petab, LLH, RDATAS, ) import logging +from pathlib import Path + +import numpy as np +import yaml +import pandas as pd +import petab.v1 as petab +import petab.v1.C as petab_C from petab.v1.lint import measurement_table_has_timepoint_specific_mappings from petab.v1.core import flatten_timepoint_specific_output_overrides +#: Columns that identify a row of a measurement/simulation table. +KEY_COLUMNS = [ + petab_C.OBSERVABLE_ID, + petab_C.PREEQUILIBRATION_CONDITION_ID, + petab_C.SIMULATION_CONDITION_ID, + petab_C.TIME, +] +#: Significant digits of the time points used to match rows; some +#: simulation tables carry the time points with more digits than the +#: measurement tables. +TIME_SIGNIFICANT_DIGITS = 6 +#: Relative and absolute tolerance of the comparison to the simulation +#: tables (``--check-simulations``), see :func:`numpy.isclose`. Looser than +#: the solver tolerances, as the tables were made with different tools and +#: settings. +COMPARISON_RTOL = 1e-3 +COMPARISON_ATOL = 1e-6 +#: Default and problem-specific solver settings. +SOLVER_SETTINGS_FILE = Path(__file__).with_name("solver_settings.yaml") +#: For ``--check-simulation-tolerances``, which checks that the solver +#: tolerances used to reproduce the simulations are tight enough to ensure +#: sufficient accuracy: the factor by which the tolerances are made +#: stricter, and the largest acceptable relative change of the simulations +#: and of the log-likelihood; 100 times below :data:`COMPARISON_RTOL`. +TOLERANCE_CHECK_FACTOR = 100 +TOLERANCE_CHECK_RTOL = 1e-5 + def parse_cli_args(): """Parse command line arguments.""" @@ -43,6 +83,39 @@ def parse_cli_args(): "If omitted, threading is left unchanged." ), ) + parser.add_argument( + "--check-simulations", + action="store_true", + help=( + "Compare the simulations against the simulation table of the " + "problem and exit with status 1 if they differ or if the " + "problem has no simulation table." + ), + ) + parser.add_argument( + "--check-simulation-tolerances", + action="store_true", + help=( + "Check that the solver tolerances are strict enough: simulate " + "again with stricter tolerances and exit with status 1 if the " + "simulations or the log-likelihood change substantially." + ), + ) + parser.add_argument( + "--all-conditions", + action="store_true", + help=( + "Simulate all conditions, also for problems with `conditions` " + "in the solver settings, for which by default only a subset of " + "the conditions is simulated (always all with --output)." + ), + ) + parser.add_argument( + "--output", + type=str, + default=None, + help="Write the simulations as PEtab simulation table to this file.", + ) args = parser.parse_args() args.num_threads = ( @@ -56,6 +129,378 @@ def parse_cli_args(): return args +def _row_keys(df: pd.DataFrame) -> pd.DataFrame: + """Get the columns that identify the rows of a measurement/simulation + table, normalized for matching rows of different tables. + + Rows with identical keys (e.g. replicates) are told apart by their + order of appearance. + """ + keys = pd.DataFrame(index=df.index) + for column in KEY_COLUMNS: + if column == petab_C.TIME: + keys[column] = [ + f"{float(t):.{TIME_SIGNIFICANT_DIGITS}g}" for t in df[column] + ] + elif column in df: + keys[column] = [ + "" if pd.isna(value) else str(value) for value in df[column] + ] + else: + keys[column] = "" + keys["replicate"] = keys.groupby(KEY_COLUMNS).cumcount() + return keys + + +def unflatten_observable_ids( + simulation_df: pd.DataFrame, observable_ids +) -> pd.DataFrame: + """Replace observable IDs of a flattened problem by the original ones. + + Simulation tables of problems with timepoint-specific overrides may use + the observable IDs of the flattened problem, + ``____``, see + :func:`petab.v1.core.flatten_timepoint_specific_output_overrides`. + """ + observable_ids = sorted(observable_ids, key=len, reverse=True) + + def unflatten(id_): + if id_ in observable_ids: + return id_ + for observable_id in observable_ids: + if id_.startswith(f"{observable_id}__"): + return observable_id + return id_ + + if petab_C.OBSERVABLE_ID not in simulation_df: + return simulation_df + simulation_df = simulation_df.copy() + simulation_df[petab_C.OBSERVABLE_ID] = [ + unflatten(str(id_)) for id_ in simulation_df[petab_C.OBSERVABLE_ID] + ] + return simulation_df + + +def compare_simulations( + simulation_df: pd.DataFrame, + expected_df: pd.DataFrame, +) -> bool: + """Compare simulations against a reference simulation table, with the + tolerances :data:`COMPARISON_RTOL` and :data:`COMPARISON_ATOL`. + + Parameters + ---------- + simulation_df: + The simulations. Must have the column ``simulation`` and the columns + of :data:`KEY_COLUMNS`. + expected_df: + The reference simulation table. + + Returns + ------- + Whether the simulations agree. + """ + for column in [ + petab_C.OBSERVABLE_ID, + petab_C.SIMULATION_CONDITION_ID, + petab_C.TIME, + petab_C.SIMULATION, + ]: + if column not in expected_df: + print(f"The simulation table has no column `{column}`.") + return False + + actual = _row_keys(simulation_df) + actual["actual"] = simulation_df[petab_C.SIMULATION].to_numpy(float) + expected = _row_keys(expected_df) + expected["expected"] = pd.to_numeric( + expected_df[petab_C.SIMULATION], errors="coerce" + ).to_numpy(float) + + merged = actual.merge( + expected, + on=KEY_COLUMNS + ["replicate"], + how="outer", + indicator=True, + sort=False, + ) + ok = True + + for side, description in [ + ("left_only", "simulated, but not in the simulation table"), + ("right_only", "in the simulation table, but not simulated"), + ]: + unmatched = merged[merged["_merge"] == side] + if not unmatched.empty: + ok = False + print(f"{len(unmatched)} rows {description}, e.g.:") + print(unmatched[KEY_COLUMNS].head().to_string(index=False)) + print() + + both = merged[merged["_merge"] == "both"] + close = np.isclose( + both["actual"], + both["expected"], + rtol=COMPARISON_RTOL, + atol=COMPARISON_ATOL, + equal_nan=True, + ) + if not close.all(): + ok = False + mismatches = both[~close].copy() + mismatches["abs_diff"] = ( + mismatches["actual"] - mismatches["expected"] + ).abs() + mismatches["rel_diff"] = mismatches["abs_diff"] / mismatches[ + "expected" + ].abs().replace(0, np.nan) + print( + f"{len(mismatches)} of {len(both)} simulations differ " + f"(rtol={COMPARISON_RTOL}, atol={COMPARISON_ATOL}); largest differences:" + ) + print( + mismatches.sort_values("abs_diff", ascending=False)[ + KEY_COLUMNS + ["actual", "expected", "abs_diff", "rel_diff"] + ] + .head(10) + .to_string(index=False) + ) + print() + + if ok: + print( + f"All {len(both)} simulations agree with the simulation table " + f"(rtol={COMPARISON_RTOL}, atol={COMPARISON_ATOL})." + ) + return ok + + +def rows_in_conditions(df: pd.DataFrame, conditions: pd.DataFrame): + """Get a boolean mask of the rows of a measurement/simulation table that + belong to one of the given simulation conditions. + + Missing condition IDs are normalized to ``""``, as in + :func:`petab.v1.get_simulation_conditions`. + """ + columns = list(conditions.columns) + keys = conditions.astype(object).fillna("").astype(str).drop_duplicates() + return ( + _row_keys(df)[columns] + .merge(keys, how="left", indicator=True)["_merge"] + .eq("both") + .to_numpy() + ) + + +def select_conditions(problem, measurement_df: pd.DataFrame, n: int): + """Restrict a problem to ``n`` of its simulation conditions. + + The conditions are evenly spaced in the order of + :func:`petab.v1.get_simulation_conditions`. + + Parameters + ---------- + problem: + The PEtab problem the AMICI model was imported from, possibly + flattened. + measurement_df: + The measurement table of the original problem (before flattening). + n: + The number of conditions. + + Returns + ------- + A copy of ``problem`` and ``measurement_df`` with only the measurements + of the selected conditions, and the selected conditions. + """ + conditions = petab.get_simulation_conditions(problem.measurement_df) + if n >= len(conditions): + return problem, measurement_df, conditions + selected = conditions.iloc[ + np.unique(np.linspace(0, len(conditions) - 1, n).round().astype(int)) + ] + index = problem.measurement_df.index[ + rows_in_conditions(problem.measurement_df, selected) + ] + + problem = copy.copy(problem) + problem.measurement_df = problem.measurement_df.loc[index] + return problem, measurement_df.loc[index], selected + + +def get_solver_settings(problem_id: str) -> dict: + """Get the solver settings for a problem. + + The defaults of :data:`SOLVER_SETTINGS_FILE`, updated by the settings + for the problem, if any. + """ + with open(SOLVER_SETTINGS_FILE) as f: + settings = yaml.safe_load(f) + return { + **settings["default"], + **((settings.get("problems") or {}).get(problem_id) or {}), + } + + +def simulate( + problem, + model, + measurement_df: pd.DataFrame, + settings: dict, + num_threads: int = 1, + verbose: bool = True, +): + """Simulate a PEtab problem at the nominal parameters. + + Parameters + ---------- + problem: + The PEtab problem the AMICI model was imported from, possibly + flattened. + model: + The AMICI model. + measurement_df: + The measurement table of the original problem (before flattening). + settings: + The solver settings, see :data:`SOLVER_SETTINGS_FILE`. + num_threads: + Number of threads to simulate the conditions in parallel. + verbose: + Whether to print the log-likelihood of every condition. + + Returns + ------- + The result of :func:`simulate_petab` and the simulations as PEtab + simulation table, in the order and with the observable IDs of + ``measurement_df``, or ``None`` if a simulation failed. + """ + solver = model.create_solver() + solver.set_return_data_reporting_mode( + ass.RDataReporting.observables_likelihood + ) + solver.set_relative_tolerance(settings["rtol"]) + solver.set_absolute_tolerance(settings["atol"]) + solver.set_max_steps(int(settings["max_steps"])) + res = simulate_petab( + problem, amici_model=model, solver=solver, num_threads=num_threads + ) + + if verbose: + for rdata in res[RDATAS]: + print( + f"{rdata.id}: llh = {rdata.llh}, chi2 = {rdata.chi2}, " + f"status = {rdata.status}" + ) + print() + + failed = [rdata for rdata in res[RDATAS] if rdata.status != 0] + if failed: + print( + f"The simulation of {len(failed)} conditions failed, e.g. " + f"{failed[0].id} with status {failed[0].status}." + ) + return res, None + + # The simulations in the order of the measurement table, with the + # observable IDs of the original (not flattened) problem. + simulation_df = rdatas_to_simulation_df( + res[RDATAS], model, problem.measurement_df + ).loc[measurement_df.index] + simulation_df[petab_C.OBSERVABLE_ID] = measurement_df[ + petab_C.OBSERVABLE_ID + ] + return res, simulation_df + + +def check_tolerances( + problem, + model, + measurement_df: pd.DataFrame, + settings: dict, + simulation_df: pd.DataFrame, + llh: float, + num_threads: int = 1, +) -> bool: + """Check that the solver tolerances are strict enough. + + Simulates again with the tolerances divided by + :data:`TOLERANCE_CHECK_FACTOR` and checks that neither the simulations + nor the log-likelihood change by more than :data:`TOLERANCE_CHECK_RTOL` + (relative to the largest absolute simulation of the observable, for the + simulations). + + Returns + ------- + Whether the tolerances are strict enough. + """ + stricter = { + **settings, + "rtol": settings["rtol"] / TOLERANCE_CHECK_FACTOR, + "atol": settings["atol"] / TOLERANCE_CHECK_FACTOR, + } + res_strict, simulation_df_strict = simulate( + problem, + model, + measurement_df, + stricter, + num_threads=num_threads, + verbose=False, + ) + if simulation_df_strict is None: + print( + f"The simulation with stricter tolerances " + f"(rtol={stricter['rtol']:g}, atol={stricter['atol']:g}) failed. " + f"Increase max_steps for the problem in " + f"{SOLVER_SETTINGS_FILE.name}." + ) + print() + return False + llh_strict = res_strict[LLH] + + simulation = simulation_df[petab_C.SIMULATION].to_numpy(float) + simulation_strict = simulation_df_strict[petab_C.SIMULATION].to_numpy( + float + ) + # scale of each observable, to judge the simulations close to zero + scale = ( + pd.Series(np.abs(simulation_strict)) + .groupby(simulation_df[petab_C.OBSERVABLE_ID].to_numpy()) + .transform("max") + .to_numpy() + ) + error = np.abs(simulation - simulation_strict) / np.where( + scale > 0, scale, 1.0 + ) + error[np.isnan(simulation) & np.isnan(simulation_strict)] = 0.0 + error[np.isnan(simulation) != np.isnan(simulation_strict)] = np.inf + max_error = np.max(error, initial=0.0) + llh_error = abs(llh - llh_strict) / max(abs(llh_strict), 1.0) + if np.isnan(llh) and np.isnan(llh_strict): + llh_error = 0.0 + elif np.isnan(llh) or np.isnan(llh_strict): + llh_error = np.inf + + print( + f"Tolerance check: rtol={settings['rtol']:g}, " + f"atol={settings['atol']:g} vs. rtol={stricter['rtol']:g}, " + f"atol={stricter['atol']:g}: " + f"largest change of the simulations {max_error:.2e} (relative to " + f"the observable), of the log-likelihood {llh_error:.2e} " + f"({llh} vs. {llh_strict})." + ) + ok = ( + max_error <= TOLERANCE_CHECK_RTOL and llh_error <= TOLERANCE_CHECK_RTOL + ) + if not ok: + print( + f"The tolerances are not strict enough: the changes exceed " + f"{TOLERANCE_CHECK_RTOL:g}. Set stricter tolerances for the " + f"problem in {SOLVER_SETTINGS_FILE.name}." + ) + print() + return ok + + def main(): """Simulate a PEtab problem with AMICI using nominal parameter values.""" args = parse_cli_args() @@ -64,8 +509,30 @@ def main(): print(args.problem_id) print("-" * len(args.problem_id), flush=True) + if args.problem_id not in benchmark_models_petab.MODELS: + sys.exit(f"Unknown problem: {args.problem_id}") + if args.problem_id not in benchmark_models_petab.v1.MODELS: + # TODO: simulate PEtab v2 problems + print("The problem has no PEtab v1 encoding, skipping it.") + print() + return + problem = benchmark_models_petab.get_problem(args.problem_id) + expected_df = benchmark_models_petab.get_simulation_df(args.problem_id) + if args.check_simulations and expected_df is None: + print( + "The problem has no simulation table. Add one, e.g. with " + "--output, see CONTRIBUTING.md." + ) + print(f"FAILED: {args.problem_id}") + print() + sys.exit(1) + + settings = get_solver_settings(args.problem_id) + print(f"Solver settings: {settings}") + print() + measurement_df = problem.measurement_df.copy() if measurement_table_has_timepoint_specific_mappings( problem.measurement_df, ): @@ -74,22 +541,70 @@ def main(): model = import_petab_problem( problem, generate_sensitivity_code=False, verbose=logging.INFO ) - solver = model.create_solver() - solver.set_return_data_reporting_mode( - ass.RDataReporting.observables_likelihood - ) - res = simulate_petab( - problem, model, solver=solver, num_threads=args.num_threads - ) - for rdata in res[RDATAS]: + n_conditions = settings.pop("conditions", None) + if ( + n_conditions is not None + and not args.all_conditions + and not args.output + ): + problem, measurement_df, conditions = select_conditions( + problem, measurement_df, int(n_conditions) + ) print( - f"{rdata.id}: llh = {rdata.llh}, chi2 = {rdata.chi2}, status = {rdata.status}" + f"Simulating {len(conditions)} of the conditions " + f"(`conditions` in {SOLVER_SETTINGS_FILE.name}; use " + "--all-conditions to simulate all)." ) + print() + if args.check_simulations: + # compare only the rows of the selected conditions + expected_df = expected_df.loc[ + rows_in_conditions(expected_df, conditions) + ] - print() + res, simulation_df = simulate( + problem, + model, + measurement_df, + settings, + num_threads=args.num_threads, + ) print("Total log-likelihood:", res[LLH]) print() + if simulation_df is None: + print(f"FAILED: {args.problem_id}") + print() + sys.exit(1) + + if args.output: + simulation_df.to_csv(args.output, sep="\t", index=False) + print(f"Wrote the simulations to {args.output}.") + print() + + ok = True + if args.check_simulation_tolerances: + ok &= check_tolerances( + problem, + model, + measurement_df, + settings, + simulation_df, + res[LLH], + num_threads=args.num_threads, + ) + + if args.check_simulations: + expected_df = unflatten_observable_ids( + expected_df, measurement_df[petab_C.OBSERVABLE_ID].unique() + ) + ok &= compare_simulations(simulation_df, expected_df) + print() + + if not ok: + print(f"FAILED: {args.problem_id}") + print() + sys.exit(1) if __name__ == "__main__": diff --git a/src/python/solver_settings.yaml b/src/python/solver_settings.yaml new file mode 100644 index 0000000..73ed2f7 --- /dev/null +++ b/src/python/solver_settings.yaml @@ -0,0 +1,59 @@ +# Solver settings for `simulate.py`. +# +# `default` applies to every problem; `problems` overrides it for single +# problems. A problem needs an override if its simulations or its +# log-likelihood change substantially with stricter tolerances, see +# `simulate.py --check-simulation-tolerances`, which simulates again with +# rtol and atol divided by 100 and requires a relative change below 1e-5. +# +# rtol, atol: relative and absolute integration tolerances (the steady-state +# tolerances follow them, see AMICI's `steady_state_tolerance_factor`) +# max_steps: maximum number of integration steps per simulation +# conditions: (optional) simulate only this many simulation conditions, +# evenly spaced, and compare only their rows of the simulation table; for +# problems too expensive to simulate completely in CI +# (`simulate.py --all-conditions` simulates all) +default: + rtol: 1.0e-8 + atol: 1.0e-16 + max_steps: 10000 + +problems: + Borghans_BiophysChem1997: + # default: change 1.1e-5 + rtol: 1.0e-10 + atol: 1.0e-18 + # for the check at rtol 1e-12 + max_steps: 100000 + Chen_MSB2009: + # the default rtol is accurate enough (change 4e-8 at rtol 1e-10, with + # atol 1e-16 and more steps), but with atol 1e-18 the integration fails + atol: 1.0e-12 + Crauste_CellSystems2017: + # change 6e-3 at the default rtol, 2e-4 at rtol 1e-10 + rtol: 1.0e-12 + atol: 1.0e-20 + Froehlich_CellSystems2018: + # default: change 2.5e-4 + rtol: 1.0e-10 + atol: 1.0e-18 + # all 9169 conditions take about 20 minutes on 4 cores; 200 take about + # 25 seconds and cover all 143 cell lines and all drugs + conditions: 200 + Isensee_JCB2018: + # default: change 1.9e-5 + rtol: 1.0e-10 + atol: 1.0e-18 + Lang_PLOSComputBiol2024: + # the default number of steps is too few (status -99, simulations NaN) + rtol: 1.0e-10 + atol: 1.0e-18 + max_steps: 100000 + Raimundez_PCB2020: + # change 2.3e-3 at the default rtol, 2.3e-5 at rtol 1e-10 + rtol: 1.0e-12 + atol: 1.0e-20 + Zheng_PNAS2012: + # default: change 1.7e-5 + rtol: 1.0e-10 + atol: 1.0e-18