diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml index 35b8a8b3e..aa4f964af 100644 --- a/.github/workflows/tests.yml +++ b/.github/workflows/tests.yml @@ -24,7 +24,7 @@ jobs: {project: "physimess-sample", name: "PhysiMeSS Sample", binary: "project", config: "config/Fibre_Degradation/mymodel_matrix_degradation.xml", max_time: 120, output_folder: ""}, {project: "physiboss-tutorial", name: "PhysiBoSS Tutorial", binary: "project", config: "config/cell_cycle/PhysiCell_settings.xml", max_time: 300, output_folder: "output"}, {project: "worm-sample", name: "PhysiCell worm", binary: "worm", config: "config/PhysiCell_settings.xml", max_time: 120, output_folder: "output"}, - {project: "virus-macrophage-sample", name: "Virus Macrophage", binary: "virus-sample", config: "config/PhysiCell_settings.xml", max_time: 120, output_folder: "output"}, + {project: "virus-macrophage-sample", name: "Virus Macrophage", binary: "virus-sample", config: "config/PhysiCell_settings.xml", max_time: 120, output_folder: ""}, {project: "mechano-sample", name: "PhysiCell Mechano", binary: "project", config: "config/PhysiCell_settings.xml", max_time: 120, output_folder: "output"}, {project: "cancer-biorobots-sample", name: "PhysiCell Cancer Biorobots", binary: "cancer_biorobots", config: "config/PhysiCell_settings.xml", max_time: 120, output_folder: ""}, {project: "biorobots-sample", name: "PhysiCell Biorobots", binary: "biorobots", config: "config/PhysiCell_settings.xml", max_time: 120, output_folder: ""}, diff --git a/.github/workflows/tests_cmake.yml b/.github/workflows/tests_cmake.yml index a7b80ce78..167dcd015 100644 --- a/.github/workflows/tests_cmake.yml +++ b/.github/workflows/tests_cmake.yml @@ -23,7 +23,7 @@ jobs: {"use_physiboss": false, cwd: "build/sample_projects/physimess", name: "PhysiMeSS Sample", binary: "physimess", config: "config/Fibre_Degradation/mymodel_matrix_degradation.xml", max_time: 120, validation_output_folder: ""}, {"use_physiboss": true, cwd: "build/sample_projects_intracellular/boolean/tutorial", name: "PhysiBoSS Tutorial", binary: "tutorial", config: "config/cell_cycle/PhysiCell_settings.xml", max_time: 300, validation_output_folder: "output_physiboss-tutorial"}, {"use_physiboss": false, cwd: "build/sample_projects/worm", name: "PhysiCell worm", binary: "worm", config: "config/PhysiCell_settings.xml", max_time: 120, validation_output_folder: "output_worm-sample"}, - {"use_physiboss": false, cwd: "build/sample_projects/virus_macrophage", name: "Virus Macrophage", binary: "virus_macrophage", config: "config/PhysiCell_settings.xml", max_time: 120, validation_output_folder: "output_virus-macrophage-sample"}, + {"use_physiboss": false, cwd: "build/sample_projects/virus_macrophage", name: "Virus Macrophage", binary: "virus_macrophage", config: "config/PhysiCell_settings.xml", max_time: 120, validation_output_folder: ""}, {"use_physiboss": false, cwd: "build/sample_projects/mechano", name: "PhysiCell Mechano", binary: "mechano", config: "config/PhysiCell_settings.xml", max_time: 120, validation_output_folder: "output_mechano-sample"}, {"use_physiboss": false, cwd: "build/sample_projects/cancer_biorobots", name: "PhysiCell Cancer Biorobots", binary: "cancer_biorobots", config: "config/PhysiCell_settings.xml", max_time: 120, validation_output_folder: ""}, {"use_physiboss": false, cwd: "build/sample_projects/biorobots", name: "PhysiCell Biorobots", binary: "biorobots", config: "config/PhysiCell_settings.xml", max_time: 120, validation_output_folder: ""}, diff --git a/core/PhysiCell_cell.cpp b/core/PhysiCell_cell.cpp index 2755d7d5d..16f0ac8f4 100644 --- a/core/PhysiCell_cell.cpp +++ b/core/PhysiCell_cell.cpp @@ -946,7 +946,17 @@ void Cell::update_voxel_in_container() container->add_agent_to_voxel(this, updated_current_mechanics_voxel_index); } current_mechanics_voxel_index=updated_current_mechanics_voxel_index; + + // Update max_cell_interactive_distance_in_voxel if needed + if( get_container()->max_cell_interactive_distance_in_voxel[current_mechanics_voxel_index] < + phenotype.geometry.radius * phenotype.mechanics.relative_maximum_adhesion_distance ) + { + get_container()->max_cell_interactive_distance_in_voxel[current_mechanics_voxel_index] = phenotype.geometry.radius + * phenotype.mechanics.relative_maximum_adhesion_distance; + } } + + return; } diff --git a/tests/cases/output_mechano-sample/PhysiCell_settings.xml b/tests/cases/output_mechano-sample/PhysiCell_settings.xml new file mode 100644 index 000000000..1f65e0932 --- /dev/null +++ b/tests/cases/output_mechano-sample/PhysiCell_settings.xml @@ -0,0 +1,370 @@ + + + + + + config + rules.csv + + + + + + -500 + 500 + -500 + 500 + -10 + 10 + 20 + 20 + 20 + true + + + + 120 + min + micron + 0.01 + 0.1 + 6 + + + + 1 + + + + output + + 60 + true + + + 60 + true + + substrate + + + + + + + false + + + + + false + true + true + 0 + + + + + + 100000.0 + 10 + + 0 + 0 + + 0 + 0 + 0 + 0 + 0 + 0 + + + + true + true + + ./config/initial.mat + + + ./config/dirichlet.mat + + + + + + + + + + 0.00072 + + + + + 1e-5 + + 516 + + + 0.05 + 0 + 1.66667e-02 + 5.83333e-03 + 0 + 2.0 + + + + 0.0 + + 0 + 86400 + + + 1.11667e-2 + 8.33333e-4 + 5.33333e-5 + 2.16667e-3 + 0 + 2.0 + + + + + 2494 + 0.75 + 540 + 0.05 + 0.0045 + 0.0055 + 0 + 0 + 2.0 + + + 0 + 10.0 + 1.6 + + 1 + 1.0 + + + 1.5 + 15.12 + + 0.01 + 10.0 + 0.0 + 12 + + + 1 + 0.05 + 1.0 + + false + true + + false + substrate + 1 + + + false + false + + 0.0 + + + + + + + 0 + 1 + 0 + 0 + + + + 0 + 0 + 0 + + 0 + 0.0 + + + 0 + 0.0 + + 1 + 0.1 + + 0 + 0.0 + + + + + 0 + 0.0 + + + + 0.0 + 0.0 + + + + 1.0 + + + + + + + + + 0 + + + + + 0 + + 516 + + + 0.05 + 0 + 1.66667e-02 + 5.83333e-03 + 0 + 2.0 + + + + 0.0 + + 0 + 86400 + + + 1.11667e-2 + 8.33333e-4 + 5.33333e-5 + 2.16667e-3 + 0 + 2.0 + + + + + 2494 + 0.75 + 540 + 0.05 + 0.0045 + 0.0055 + 0 + 0 + 2.0 + + + 0 + 100.0 + 1.25 + + 1.0 + 1.0 + + + 1.5 + 15.12 + + 0.01 + 10.0 + 0.0 + 12 + + + 1 + 0.05 + 1.0 + + false + true 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Cell Hypothesis Rules (detailed)

+

In cancer cells: +

+

+

In BM cells: +

+

+ + diff --git a/tests/cases/output_mechano-sample/detailed_rules.txt b/tests/cases/output_mechano-sample/detailed_rules.txt new file mode 100644 index 000000000..ab6a0a762 --- /dev/null +++ b/tests/cases/output_mechano-sample/detailed_rules.txt @@ -0,0 +1,6 @@ +Cell Hypothesis Rules (detailed) + +In cancer cells: + +In BM cells: + diff --git a/tests/cases/output_mechano-sample/dictionaries.txt b/tests/cases/output_mechano-sample/dictionaries.txt new file mode 100644 index 000000000..e5a91160c --- /dev/null +++ b/tests/cases/output_mechano-sample/dictionaries.txt @@ -0,0 +1,130 @@ +Signals (with synonyms): +======================= +20 : apoptotic +15 : attacking +12 : contact with BM +9 : contact with apoptotic cell +9 : contact with apoptotic cells +12 : contact with basement membrane +5 : contact with cancer +5 : contact with cell type 0 +6 : contact with cell type 1 +8 : contact with dead cell +8 : contact with dead cells +7 : contact with live cell +7 : contact with live cells +10 : contact with necrotic cell +10 : contact with necrotic cells +11 : contact with other dead cell +11 : contact with other dead cells +18 : current time +19 : custom 0 +19 : custom: sample +19 : custom:sample +13 : damage +14 : damage delivered +16 : dead +18 : global time +2 : grad(substrate) +2 : gradient of substrate +1 : internalized substrate +1 : intracellular substrate +15 : is attacking +16 : is dead +20 : is_apoptotic +21 : is_necrotic +21 : necrotic +3 : pressure +0 : substrate +2 : substrate gradient +18 : time +17 : total attack time +14 : total damage delivered +4 : volume + + +Behaviors (with synonyms): +========================= +19 : adhesive affinity to BM +18 : adhesive affinity to cancer +18 : adhesive affinity to cell type 0 +19 : adhesive affinity to cell type 1 +10 : apoptosis +36 : asymmetric division to BM +35 : asymmetric division to cancer +30 : attack BM +29 : attack cancer +29 : attack cell type 0 +30 : attack cell type 1 +44 : attack damage rate +45 : attack duration +41 : cell attachment rate +42 : cell detachment rate +22 : cell-BM adhesion +23 : cell-BM repulsion +16 : cell-cell adhesion +17 : cell-cell adhesion elastic constant +21 : cell-cell repulsion +22 : cell-membrane adhesion +23 : cell-membrane repulsion +15 : chemotactic response to substrate +15 : chemotactic sensitivity to substrate +37 : custom 0 +37 : custom: sample +37 : custom:sample +4 : cycle entry +46 : damage rate +47 : damage repair rate +4 : exit from cycle phase 0 +5 : exit from cycle phase 1 +6 : exit from cycle phase 2 +7 : exit from cycle phase 3 +8 : exit from cycle phase 4 +9 : exit from cycle phase 5 +32 : fuse to BM +31 : fuse to cancer +31 : fuse to cell type 0 +32 : fuse to cell type 1 +40 : immunogenicity to BM +39 : immunogenicity to cancer +39 : immunogenicity to cell type 0 +40 : immunogenicity to cell type 1 +38 : is movable +38 : is_movable +43 : maximum number of cell attachments +13 : migration bias +14 : migration persistence time +12 : migration speed +38 : movable +11 : necrosis +28 : phagocytose BM +24 : phagocytose apoptotic cell +27 : phagocytose cancer +27 : phagocytose cell type 0 +28 : phagocytose cell type 1 +25 : phagocytose necrotic cell +26 : phagocytose other dead cell +28 : phagocytosis of BM +24 : phagocytosis of apoptotic cell +24 : phagocytosis of apoptotic cells +27 : phagocytosis of cancer +25 : phagocytosis of necrotic cell +25 : phagocytosis of necrotic cells +26 : phagocytosis of other dead cell +26 : phagocytosis of other dead cells +20 : relative maximum adhesion distance +3 : substrate export +0 : substrate secretion +1 : substrate secretion saturation density +1 : substrate secretion target +2 : substrate uptake +34 : transform to BM +33 : transform to cancer +33 : transform to cell type 0 +34 : transform to cell type 1 +34 : transition to BM +33 : transition to cancer +33 : transition to cell type 0 +34 : transition to cell type 1 + + diff --git a/tests/cases/output_mechano-sample/empty.txt b/tests/cases/output_mechano-sample/empty.txt new file mode 100644 index 000000000..e69de29bb diff --git a/tests/cases/output_mechano-sample/final.svg b/tests/cases/output_mechano-sample/final.svg new file mode 100644 index 000000000..fcc993e6b --- /dev/null +++ b/tests/cases/output_mechano-sample/final.svg @@ -0,0 +1,2232 @@ + + + + + + Current time: 0 days, 2 hours, and 0.01 minutes, z = 0.00 μm + + + 548 agents + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 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file mode 100644 index 000000000..e523af839 --- /dev/null +++ b/tests/cases/output_mechano-sample/final.xml @@ -0,0 +1,161 @@ + + + + + PhysiCell + 1.14.2 + http://physicell.org + + + 0000-0002-9925-0151 + Paul + Macklin + macklinp@iu.edu + http://MathCancer.org + Indiana University & PhysiCell Project + Intelligent Systems Engineering + + + + A Ghaffarizadeh, R Heiland, SH Friedman, SM Mumenthaler, and P Macklin. PhysiCell: an Open Source Physics-Based Cell Simulator for Multicellular Systems, PLoS Comput. Biol. 14(2): e1005991, 2018. DOI: 10.1371/journal.pcbi.1005991 + 10.1371/journal.pcbi.1005991 + https://dx.doi.org/PMC5841829 + 29474446 + PMC5841829 + + + + + 120.010000 + 3.051133 + 2026-08-17T17:10:36Z + 2026-08-17T17:10:36Z + + + + + -500.000000 -500.000000 -10.000000 500.000000 500.000000 10.000000 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + 0 + + initial_mesh0.mat + + + + + + + 100000.000000 + 10.000000 + + + + + final_microenvironment0.mat + + + + + + + + + + cancer + BM + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + final_cells.mat + + + final_cell_neighbor_graph.txt + + + final_attached_cells_graph.txt + + + final_spring_attached_cells_graph.txt + + + + + + diff --git a/tests/cases/output_mechano-sample/final_attached_cells_graph.txt b/tests/cases/output_mechano-sample/final_attached_cells_graph.txt new file mode 100644 index 000000000..616a49173 --- /dev/null +++ b/tests/cases/output_mechano-sample/final_attached_cells_graph.txt @@ -0,0 +1,548 @@ +0: +1: +2: +3: +4: +5: +6: +7: +8: +9: +10: +11: +12: +13: +14: +15: +16: +17: +18: +19: +20: +21: +22: +23: +24: +25: +26: +27: +28: +29: +30: +31: +32: +33: +34: +35: +36: +37: +38: +39: +40: +41: +42: +43: +44: +45: +46: +47: +48: +49: +50: +51: +52: +53: +54: +55: +56: +57: +58: +59: +60: +61: +62: +63: +64: +65: +66: +67: +68: +69: +70: +71: +72: +73: +74: +75: +76: +77: +78: +79: +80: +81: +82: +83: +84: +85: +86: +87: +88: +89: +90: +91: +92: +93: +94: +95: +96: +97: +98: +99: +100: +101: +102: +103: +104: +105: +106: +107: +108: +109: 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PhysiCell: an Open Source Physics-Based Cell Simulator for Multicellular Systems, PLoS Comput. Biol. 14(2): e1005991, 2018. DOI: 10.1371/journal.pcbi.1005991 + 10.1371/journal.pcbi.1005991 + https://dx.doi.org/PMC5841829 + 29474446 + PMC5841829 + + + + + 0.000000 + 1.021370 + 2026-08-17T17:10:33Z + 2026-08-17T17:10:33Z + + + + + -500.000000 -500.000000 -10.000000 500.000000 500.000000 10.000000 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + 0 + + initial_mesh0.mat + + + + + + + 100000.000000 + 10.000000 + + + + + initial_microenvironment0.mat + + + + + + + + + + cancer + BM + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + initial_cells.mat + + + initial_cell_neighbor_graph.txt + + + initial_attached_cells_graph.txt + + + initial_spring_attached_cells_graph.txt + + + + + + diff --git a/tests/cases/output_mechano-sample/initial_attached_cells_graph.txt b/tests/cases/output_mechano-sample/initial_attached_cells_graph.txt new file mode 100644 index 000000000..616a49173 --- /dev/null +++ b/tests/cases/output_mechano-sample/initial_attached_cells_graph.txt @@ -0,0 +1,548 @@ +0: +1: +2: +3: +4: +5: +6: +7: +8: +9: +10: +11: +12: +13: +14: +15: +16: +17: +18: +19: +20: +21: +22: +23: +24: +25: +26: +27: +28: +29: +30: +31: +32: +33: +34: +35: +36: +37: +38: +39: +40: +41: +42: +43: +44: +45: +46: +47: +48: +49: +50: +51: +52: +53: +54: +55: +56: +57: +58: +59: +60: +61: +62: +63: +64: +65: +66: +67: +68: +69: +70: +71: +72: +73: +74: +75: +76: +77: +78: +79: +80: +81: +82: +83: +84: +85: +86: +87: +88: +89: +90: +91: +92: +93: +94: +95: +96: +97: +98: +99: +100: +101: +102: +103: +104: +105: +106: +107: 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mode 100644 index 000000000..03bf9ccd6 --- /dev/null +++ b/tests/cases/output_mechano-sample/legend.svg @@ -0,0 +1,25 @@ + + + + + + + cancer + + + + + BM + + diff --git a/tests/cases/output_mechano-sample/output00000000.xml b/tests/cases/output_mechano-sample/output00000000.xml new file mode 100644 index 000000000..af8609437 --- /dev/null +++ b/tests/cases/output_mechano-sample/output00000000.xml @@ -0,0 +1,161 @@ + + + + + PhysiCell + 1.14.2 + http://physicell.org + + + 0000-0002-9925-0151 + Paul + Macklin + macklinp@iu.edu + http://MathCancer.org + Indiana University & PhysiCell Project + Intelligent Systems Engineering + + + + A Ghaffarizadeh, R Heiland, SH Friedman, SM Mumenthaler, and P Macklin. PhysiCell: an Open Source Physics-Based Cell Simulator for Multicellular Systems, PLoS Comput. Biol. 14(2): e1005991, 2018. DOI: 10.1371/journal.pcbi.1005991 + 10.1371/journal.pcbi.1005991 + https://dx.doi.org/PMC5841829 + 29474446 + PMC5841829 + + + + + 0.000000 + 0.000027 + 2026-08-17T17:10:33Z + 2026-08-17T17:10:33Z + + + + + -500.000000 -500.000000 -10.000000 500.000000 500.000000 10.000000 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + 0 + + initial_mesh0.mat + + + + + + + 100000.000000 + 10.000000 + + + + + output00000000_microenvironment0.mat + + + + + + + + + + cancer + BM + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + output00000000_cells.mat + + + output00000000_cell_neighbor_graph.txt + + + output00000000_attached_cells_graph.txt + + + output00000000_spring_attached_cells_graph.txt + + + + + + diff --git a/tests/cases/output_mechano-sample/output00000000_attached_cells_graph.txt b/tests/cases/output_mechano-sample/output00000000_attached_cells_graph.txt new file mode 100644 index 000000000..616a49173 --- /dev/null +++ b/tests/cases/output_mechano-sample/output00000000_attached_cells_graph.txt @@ -0,0 +1,548 @@ +0: +1: +2: +3: +4: +5: +6: +7: +8: +9: +10: +11: +12: +13: +14: +15: +16: +17: +18: +19: +20: +21: +22: +23: +24: +25: +26: +27: +28: +29: +30: +31: +32: +33: +34: +35: +36: +37: +38: +39: +40: +41: +42: +43: +44: +45: +46: +47: +48: +49: +50: +51: +52: +53: +54: +55: +56: +57: +58: +59: +60: +61: +62: +63: +64: +65: +66: +67: +68: +69: +70: +71: +72: +73: +74: +75: +76: +77: +78: +79: +80: +81: +82: +83: +84: +85: +86: +87: +88: +89: +90: +91: +92: +93: +94: +95: +96: +97: +98: 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b/tests/cases/output_mechano-sample/output00000001.xml @@ -0,0 +1,161 @@ + + + + + PhysiCell + 1.14.2 + http://physicell.org + + + 0000-0002-9925-0151 + Paul + Macklin + macklinp@iu.edu + http://MathCancer.org + Indiana University & PhysiCell Project + Intelligent Systems Engineering + + + + A Ghaffarizadeh, R Heiland, SH Friedman, SM Mumenthaler, and P Macklin. PhysiCell: an Open Source Physics-Based Cell Simulator for Multicellular Systems, PLoS Comput. Biol. 14(2): e1005991, 2018. DOI: 10.1371/journal.pcbi.1005991 + 10.1371/journal.pcbi.1005991 + https://dx.doi.org/PMC5841829 + 29474446 + PMC5841829 + + + + + 60.000000 + 1.447189 + 2026-08-17T17:10:34Z + 2026-08-17T17:10:34Z + + + + + -500.000000 -500.000000 -10.000000 500.000000 500.000000 10.000000 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + 0 + + initial_mesh0.mat + + + + + + + 100000.000000 + 10.000000 + + + + + output00000001_microenvironment0.mat + + + + + + + + + + cancer + BM + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + output00000001_cells.mat + + + output00000001_cell_neighbor_graph.txt + + + output00000001_attached_cells_graph.txt + + + output00000001_spring_attached_cells_graph.txt + + + + + + diff --git a/tests/cases/output_mechano-sample/output00000001_attached_cells_graph.txt b/tests/cases/output_mechano-sample/output00000001_attached_cells_graph.txt new file mode 100644 index 000000000..616a49173 --- /dev/null +++ b/tests/cases/output_mechano-sample/output00000001_attached_cells_graph.txt @@ -0,0 +1,548 @@ +0: +1: +2: +3: +4: +5: +6: +7: +8: +9: +10: +11: +12: +13: +14: +15: +16: +17: +18: +19: +20: +21: +22: +23: +24: +25: +26: +27: +28: +29: +30: +31: +32: +33: +34: +35: +36: +37: +38: +39: +40: +41: +42: +43: +44: +45: +46: +47: +48: +49: +50: +51: +52: +53: +54: +55: +56: +57: +58: +59: +60: +61: +62: +63: +64: +65: +66: +67: +68: +69: +70: +71: +72: +73: +74: +75: +76: +77: +78: +79: +80: +81: +82: +83: +84: +85: +86: +87: +88: +89: +90: +91: +92: +93: +94: +95: +96: +97: 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b/tests/cases/output_mechano-sample/output00000001_boolean_intracellular.csv @@ -0,0 +1 @@ +ID,state diff --git a/tests/cases/output_mechano-sample/output00000001_cell_neighbor_graph.txt b/tests/cases/output_mechano-sample/output00000001_cell_neighbor_graph.txt new file mode 100644 index 000000000..3da0ef530 --- /dev/null +++ b/tests/cases/output_mechano-sample/output00000001_cell_neighbor_graph.txt @@ -0,0 +1,548 @@ +0: +1: +2: +3: 4,69,70 +4: 3,70,5,71 +5: 6,71,72,4 +6: 5,72,7,73 +7: 73,74,6,8 +8: 9,75,7,74 +9: 8,75,76,10 +10: 11,77,9,76 +11: 10,77,12,78 +12: 13,78,79,11 +13: 12,79,14,80 +14: 80,81,13,15 +15: 16,82,14,81 +16: 15,82,83,17 +17: 18,84,16,83 +18: 17,84,85,19 +19: 20,86,18,85 +20: 19,86,21,87 +21: 22,87,88,20 +22: 21,88,23,89 +23: 89,90,22,24 +24: 25,91,23,90 +25: 24,91,92,26 +26: 27,93,25,92 +27: 26,93,28,94 +28: 29,94,95,27 +29: 28,95,30,96 +30: 96,97,29,31 +31: 32,98,30,97 +32: 31,98,99,33 +33: 34,100,32,99 +34: 33,100,101,35 +35: 36,102,34,101 +36: 35,102,37,103 +37: 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522,523,534 +534: 535,542,523,533,524 +535: 534,542,543,524,525,536 +536: 537,544,525,535,543,526 +537: 536,544,545,526,527,538 +538: 539,546,527,537,545,528 +539: 538,546,528,529,540,547 +540: 541,547,539,529,530 +541: 540,530,531 +542: 534,535,543 +543: 535,542,536,544 +544: 536,537,545,543 +545: 537,544,538,546 +546: 538,539,545,547 +547: 540,539,546 \ No newline at end of file diff --git a/tests/cases/output_mechano-sample/output00000001_cells.mat b/tests/cases/output_mechano-sample/output00000001_cells.mat new file mode 100644 index 000000000..378dbc06b Binary files /dev/null and b/tests/cases/output_mechano-sample/output00000001_cells.mat differ diff --git a/tests/cases/output_mechano-sample/output00000001_microenvironment0.mat b/tests/cases/output_mechano-sample/output00000001_microenvironment0.mat new file mode 100644 index 000000000..cb046b6dd Binary files /dev/null and b/tests/cases/output_mechano-sample/output00000001_microenvironment0.mat differ diff --git a/tests/cases/output_mechano-sample/output00000001_spring_attached_cells_graph.txt b/tests/cases/output_mechano-sample/output00000001_spring_attached_cells_graph.txt new file mode 100644 index 000000000..616a49173 --- /dev/null +++ b/tests/cases/output_mechano-sample/output00000001_spring_attached_cells_graph.txt @@ -0,0 +1,548 @@ +0: +1: +2: +3: +4: +5: +6: +7: +8: +9: +10: +11: +12: +13: +14: +15: +16: +17: +18: +19: +20: +21: +22: +23: +24: +25: +26: +27: +28: +29: +30: +31: +32: +33: +34: +35: +36: +37: +38: +39: +40: +41: +42: +43: +44: +45: +46: +47: +48: +49: +50: +51: +52: +53: +54: +55: +56: +57: +58: +59: +60: +61: +62: +63: +64: +65: +66: +67: +68: +69: +70: +71: +72: +73: +74: +75: +76: +77: +78: +79: +80: +81: +82: +83: +84: +85: +86: +87: +88: +89: +90: +91: +92: +93: +94: +95: +96: +97: +98: +99: +100: +101: +102: +103: +104: +105: +106: +107: +108: +109: +110: +111: +112: +113: +114: +115: +116: +117: +118: +119: +120: +121: +122: +123: +124: +125: +126: +127: +128: 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Intelligent Systems Engineering + + + + A Ghaffarizadeh, R Heiland, SH Friedman, SM Mumenthaler, and P Macklin. PhysiCell: an Open Source Physics-Based Cell Simulator for Multicellular Systems, PLoS Comput. Biol. 14(2): e1005991, 2018. DOI: 10.1371/journal.pcbi.1005991 + 10.1371/journal.pcbi.1005991 + https://dx.doi.org/PMC5841829 + 29474446 + PMC5841829 + + + + + 120.000000 + 3.037776 + 2026-08-17T17:10:36Z + 2026-08-17T17:10:36Z + + + + + -500.000000 -500.000000 -10.000000 500.000000 500.000000 10.000000 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + -490 -470 -450 -430 -410 -390 -370 -350 -330 -310 -290 -270 -250 -230 -210 -190 -170 -150 -130 -110 -90 -70 -50 -30 -10 10 30 50 70 90 110 130 150 170 190 210 230 250 270 290 310 330 350 370 390 410 430 450 470 490 + 0 + + initial_mesh0.mat + + + + + + + 100000.000000 + 10.000000 + + + + + output00000002_microenvironment0.mat + + + + + + + + + + cancer + BM + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + output00000002_cells.mat + + + output00000002_cell_neighbor_graph.txt + + + output00000002_attached_cells_graph.txt + + + output00000002_spring_attached_cells_graph.txt + + + + + + diff --git a/tests/cases/output_mechano-sample/output00000002_attached_cells_graph.txt b/tests/cases/output_mechano-sample/output00000002_attached_cells_graph.txt new file mode 100644 index 000000000..616a49173 --- /dev/null +++ b/tests/cases/output_mechano-sample/output00000002_attached_cells_graph.txt @@ -0,0 +1,548 @@ +0: +1: +2: +3: +4: +5: +6: +7: +8: +9: +10: +11: +12: +13: +14: +15: +16: +17: +18: +19: +20: +21: +22: +23: +24: +25: +26: +27: +28: +29: +30: +31: +32: +33: +34: +35: +36: +37: +38: +39: +40: +41: +42: +43: +44: +45: +46: +47: +48: +49: +50: +51: +52: +53: +54: +55: +56: +57: +58: +59: +60: +61: +62: +63: +64: +65: +66: +67: +68: +69: +70: +71: +72: +73: +74: +75: +76: +77: +78: +79: +80: +81: +82: +83: +84: +85: +86: +87: +88: +89: +90: +91: +92: +93: +94: +95: +96: +97: 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b/tests/cases/output_mechano-sample/rules.html @@ -0,0 +1,12 @@ + +

Cell Hypothesis Rules

+

In cancer cells: +

+

+

In BM cells: +

+

+ + diff --git a/tests/cases/output_mechano-sample/rules.txt b/tests/cases/output_mechano-sample/rules.txt new file mode 100644 index 000000000..df5cc6695 --- /dev/null +++ b/tests/cases/output_mechano-sample/rules.txt @@ -0,0 +1,6 @@ +Cell Hypothesis Rules + +In cancer cells: + +In BM cells: + diff --git a/tests/cases/output_worm-sample/cell_rules_parsed.csv b/tests/cases/output_worm-sample/cell_rules_parsed.csv new file mode 100644 index 000000000..e69de29bb diff --git a/tests/cases/output_worm-sample/cells.csv b/tests/cases/output_worm-sample/cells.csv new file mode 100644 index 000000000..da8c78e7a --- /dev/null +++ b/tests/cases/output_worm-sample/cells.csv @@ -0,0 +1,11 @@ +0,0,0,0 +12,3,0,0 +24,5,0,0 +36,6,0,0 +48,5,0,0 +60,3,0,0 +72,0,0,0 +84,-3,0,0 +96,-5,0,0 +108,-6,0,0 +120,-5,0,0 \ No newline at end of file diff --git a/tests/cases/output_worm-sample/final.svg b/tests/cases/output_worm-sample/final.svg new file mode 100644 index 000000000..2b036254e --- /dev/null +++ b/tests/cases/output_worm-sample/final.svg @@ -0,0 +1,1084 @@ + + + + + + Current time: 0 days, 2 hours, and 0.01 minutes, z = 0.00 μm + + + 261 agents + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 200 μm + + + 0 days, 0 hours, 0 minutes, and 1.2696 seconds + + + + diff --git a/tests/cases/output_worm-sample/legend.svg b/tests/cases/output_worm-sample/legend.svg new file mode 100644 index 000000000..3e6a77f26 --- /dev/null +++ b/tests/cases/output_worm-sample/legend.svg @@ -0,0 +1,19 @@ + + + + + + + worm + + diff --git a/tests/cases/output_worm-sample/snapshot00000000.svg b/tests/cases/output_worm-sample/snapshot00000000.svg index fd5aa2e43..4bb2d0c4b 100644 --- a/tests/cases/output_worm-sample/snapshot00000000.svg +++ b/tests/cases/output_worm-sample/snapshot00000000.svg @@ -1077,7 +1077,7 @@ - 0 days, 0 hours, 0 minutes, and 0.0051 seconds + 0 days, 0 hours, 0 minutes, and 0.0018 seconds diff --git a/tests/cases/output_worm-sample/snapshot00000001.svg b/tests/cases/output_worm-sample/snapshot00000001.svg index 79663cd68..11cac464d 100644 --- a/tests/cases/output_worm-sample/snapshot00000001.svg +++ b/tests/cases/output_worm-sample/snapshot00000001.svg @@ -113,8 +113,8 @@ - - + + @@ -165,8 +165,8 @@ - - + + @@ -209,8 +209,8 @@ - - + + @@ -225,8 +225,8 @@ - - + + @@ -265,8 +265,8 @@ - - + + @@ -297,12 +297,12 @@ - - + + - - + + @@ -345,8 +345,8 @@ - - + + @@ -381,8 +381,8 @@ - - + + @@ -497,8 +497,8 @@ - - + + @@ -513,20 +513,20 @@ - - + + - - + + - - + + @@ -641,8 +641,8 @@ - - + + @@ -697,16 +697,16 @@ - - + + - - + + - - + + @@ -733,8 +733,8 @@ - - + + @@ -757,8 +757,8 @@ - - + + @@ -789,12 +789,12 @@ - - + + - - + + @@ -873,8 +873,8 @@ - - + + @@ -893,8 +893,8 @@ - - + + @@ -921,8 +921,8 @@ - - + + @@ -965,8 +965,8 @@ - - + + @@ -997,8 +997,8 @@ - - + + @@ -1017,52 +1017,52 @@ - 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