diff --git a/api/app/settings/common.py b/api/app/settings/common.py
index cd660dd4b3d7..b165c5745c28 100644
--- a/api/app/settings/common.py
+++ b/api/app/settings/common.py
@@ -333,6 +333,7 @@
     "DEFAULT_SCHEMA_CLASS": "drf_spectacular.openapi.AutoSchema",
 }
 MIDDLEWARE = [
+    "core.middleware.query_params.NullCharacterQueryParamMiddleware",
     "common.core.middleware.APIResponseVersionHeaderMiddleware",
     "common.gunicorn.middleware.RouteLoggerMiddleware",
     "django.middleware.security.SecurityMiddleware",
diff --git a/api/core/middleware/query_params.py b/api/core/middleware/query_params.py
new file mode 100644
index 000000000000..64066c8a59c1
--- /dev/null
+++ b/api/core/middleware/query_params.py
@@ -0,0 +1,29 @@
+from django.http import QueryDict
+
+
+class NullCharacterQueryParamMiddleware:
+    """
+    Strip NUL (0x00) characters from query parameter values.
+
+    Prevents ValueError exceptions when query parameter values containing
+    null characters are passed to database queries.
+    """
+
+    def __init__(self, get_response):  # type: ignore[no-untyped-def]
+        self.get_response = get_response
+
+    def __call__(self, request):  # type: ignore[no-untyped-def]
+        if "\x00" in request.META.get("QUERY_STRING", ""):
+            sanitized = QueryDict(mutable=True)
+            for key, values in request.GET.lists():
+                sanitized_key = key.replace("\x00", "")
+                sanitized.setlist(
+                    sanitized_key,
+                    [v.replace("\x00", "") for v in values],
+                )
+            request.GET = sanitized
+            request.META["QUERY_STRING"] = request.META["QUERY_STRING"].replace(
+                "\x00", ""
+            )
+
+        return self.get_response(request)
diff --git a/api/tests/unit/core/middleware/test_unit_core_middleware_query_params.py b/api/tests/unit/core/middleware/test_unit_core_middleware_query_params.py
new file mode 100644
index 000000000000..ec751a8a7957
--- /dev/null
+++ b/api/tests/unit/core/middleware/test_unit_core_middleware_query_params.py
@@ -0,0 +1,73 @@
+from django.http import HttpResponse, QueryDict
+
+from core.middleware.query_params import NullCharacterQueryParamMiddleware
+
+
+def test_null_char_middleware__strips_null_from_query_param_values(mocker):  # type: ignore[no-untyped-def]
+    # Given
+    mocked_get_response = mocker.MagicMock(return_value=HttpResponse())
+    mock_request = mocker.MagicMock()
+    mock_request.META = {"QUERY_STRING": "identifier=test\x00value"}
+    query_dict = QueryDict("identifier=test\x00value")
+    mock_request.GET = query_dict
+
+    middleware = NullCharacterQueryParamMiddleware(mocked_get_response)  # type: ignore[no-untyped-call]
+
+    # When
+    middleware(mock_request)
+
+    # Then
+    assert mock_request.GET["identifier"] == "testvalue"
+    assert "\x00" not in mock_request.META["QUERY_STRING"]
+
+
+def test_null_char_middleware__strips_null_from_query_param_keys(mocker):  # type: ignore[no-untyped-def]
+    # Given
+    mocked_get_response = mocker.MagicMock(return_value=HttpResponse())
+    mock_request = mocker.MagicMock()
+    mock_request.META = {"QUERY_STRING": "ident\x00ifier=test"}
+    query_dict = QueryDict("ident\x00ifier=test")
+    mock_request.GET = query_dict
+
+    middleware = NullCharacterQueryParamMiddleware(mocked_get_response)  # type: ignore[no-untyped-call]
+
+    # When
+    middleware(mock_request)
+
+    # Then
+    assert "identifier" in mock_request.GET
+    assert mock_request.GET["identifier"] == "test"
+
+
+def test_null_char_middleware__no_null_chars__passes_through(mocker):  # type: ignore[no-untyped-def]
+    # Given
+    mocked_get_response = mocker.MagicMock(return_value=HttpResponse())
+    mock_request = mocker.MagicMock()
+    mock_request.META = {"QUERY_STRING": "identifier=testvalue"}
+    original_get = QueryDict("identifier=testvalue")
+    mock_request.GET = original_get
+
+    middleware = NullCharacterQueryParamMiddleware(mocked_get_response)  # type: ignore[no-untyped-call]
+
+    # When
+    middleware(mock_request)
+
+    # Then
+    assert mock_request.GET is original_get
+
+
+def test_null_char_middleware__empty_query_string__passes_through(mocker):  # type: ignore[no-untyped-def]
+    # Given
+    mocked_get_response = mocker.MagicMock(return_value=HttpResponse())
+    mock_request = mocker.MagicMock()
+    mock_request.META = {"QUERY_STRING": ""}
+    original_get = QueryDict("")
+    mock_request.GET = original_get
+
+    middleware = NullCharacterQueryParamMiddleware(mocked_get_response)  # type: ignore[no-untyped-call]
+
+    # When
+    middleware(mock_request)
+
+    # Then
+    assert mock_request.GET is original_get